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The applications of large language models (LLMs) are promising for biomedical and healthcare research. Despite the availability of open-source LLMs trained using a wide range of biomedical data, current research on the applications of LLMs…

Nucleotide sequences constitute the fundamental genetic basis of biological systems, rendering viral genomic analysis critical for biomedical advancement. Despite progress in biological foundation models, specifically nucleotide foundation…

Interpreting gene clusters from RNA sequencing (RNA-seq) remains challenging, especially in antimicrobial resistance studies where mechanistic insight is important for hypothesis generation. Existing pathway enrichment methods can summarize…

Large language models (LLMs) have shown remarkable performance on many tasks in different domains. However, their performance in closed-book biomedical machine reading comprehension (MRC) has not been evaluated in depth. In this work, we…

The advent of Large Language Models (LLMs) holds promise for revolutionizing various fields traditionally dominated by human expertise. Urban planning, a professional discipline that fundamentally shapes our daily surroundings, is one such…

Large-scale multilingual evaluations, such as MEGA, often include only a handful of African languages due to the scarcity of high-quality evaluation data and the limited discoverability of existing African datasets. This lack of…

Existing long-context benchmarks for Large Language Models (LLMs) focus on evaluating comprehension of long inputs, while overlooking the evaluation of long reasoning abilities. To address this gap, we introduce LongReasonArena, a benchmark…

Large language models (LLMs) have been shown to be capable of impressive few-shot generalisation to new tasks. However, they still tend to perform poorly on multi-step logical reasoning problems. Here we carry out a comprehensive evaluation…

Large language models (LLMs) have become increasingly pivotal across various domains, especially in handling complex data types. This includes structured data processing, as exemplified by ChartQA and ChatGPT-Ada, and multimodal…

We investigate how to teach large language models (LLMs) to perform scientific reasoning by leveraging expert discussions as a learning signal. Focusing on the genomics domain, we develop an automated pipeline to extract trainable data and…

Inspired by the success of large language models (LLM) for DNA and proteins, several LLM for RNA have been developed recently. RNA-LLM uses large datasets of RNA sequences to learn, in a self-supervised way, how to represent each RNA base…

Mathematical reasoning is a hallmark of human intelligence, and whether large language models (LLMs) can meaningfully perform it remains a central question in artificial intelligence and cognitive science. As LLMs are increasingly…

We present a new approach for benchmarking Large Language Model (LLM) capabilities on research-level mathematics. Existing benchmarks largely rely on static, hand-curated sets of contest or textbook-style problems as proxies for…

In recent years, large language models (LLMs) have achieved state-of-the-art results in various biological sequence analysis tasks, such as sequence classification, structure prediction, and function prediction. Similar to advancements in…

As key elements within the central dogma, DNA, RNA, and proteins play crucial roles in maintaining life by guaranteeing accurate genetic expression and implementation. Although research on these molecules has profoundly impacted fields like…

Multimodal Large Language Models (MLLMs) have shown impressive capabilities in image understanding and generation. However, current benchmarks fail to accurately evaluate the chart comprehension of MLLMs due to limited chart types and…

Large language models (LLMs) achieve impressive scores on standard benchmarks yet routinely fail questions that any human would answer correctly in seconds. We introduce BrainBench, a benchmark of 100 brainteaser questions spanning 20…

Large language models (LLMs) have shown exceptional performance on a variety of natural language tasks. Yet, their capabilities for HTML understanding -- i.e., parsing the raw HTML of a webpage, with applications to automation of web-based…

Large Language Models (LLMs) with strong abilities in natural language processing tasks have emerged and have been applied in various kinds of areas such as science, finance and software engineering. However, the capability of LLMs to…

Large language models (LLMs) have demonstrated broad utility across molecular domains, spanning drug discovery and materials design. Analyzing LLMs' latent representations is crucial for elucidating their underlying mechanisms, improving…