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In image segmentation, there is often more than one plausible solution for a given input. In medical imaging, for example, experts will often disagree about the exact location of object boundaries. Estimating this inherent uncertainty and…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Miguel Monteiro , Loïc Le Folgoc , Daniel Coelho de Castro , Nick Pawlowski , Bernardo Marques , Konstantinos Kamnitsas , Mark van der Wilk , Ben Glocker

Coreset selection, which involves selecting a small subset from an existing training dataset, is an approach to reducing training data, and various approaches have been proposed for this method. In practical situations where these methods…

Deep learning models for medical imaging often exhibit overconfidence, creating safety risks in ambiguous diagnostic scenarios. While Conformal Prediction (CP) provides distribution-free statistical guarantees, standard methods such as…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 One Octadion , Novanto Yudistira , Lailil Muflikhah

Hyperspectral imaging is an advanced technique for precisely identifying and analyzing materials or objects. However, its integration with robotic grasping systems has so far been explored due to the deployment complexities and prohibitive…

Robotics · Computer Science 2025-12-08 Zheng Sun , Zhipeng Dong , Shixiong Wang , Zhongyi Chu , Fei Chen

Scribble-supervised medical image segmentation tackles the limitation of sparse masks. Conventional approaches alternate between: labeling pseudo-masks and optimizing network parameters. However, such iterative two-stage paradigm is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Zefan Yang , Di Lin , Dong Ni , Yi Wang

Inference-time scaling techniques have shown promise in enhancing the reasoning capabilities of large language models (LLMs). While recent research has primarily focused on training-time optimization, our work highlights inference-time…

Computation and Language · Computer Science 2026-02-12 Jiachun Li , Pengfei Cao , Zhuoran Jin , Yubo Chen , Jiexin Xu , Huaijun Li , Xiaojian Jiang , Kang Liu , Jun Zhao

Quantitative Systems Pharmacology (QSP) promises to accelerate drug development, enable personalized medicine, and improve the predictability of clinical outcomes. Realizing this potential requires effectively managing the complexity of…

Quantitative Methods · Quantitative Biology 2025-06-10 Noah DeTal , Christian N. K. Anderson , Mark K. Transtrum

The reliable deployment of deep learning in medical imaging requires uncertainty quantification that provides rigorous error guarantees while remaining anatomically meaningful. Conformal prediction (CP) is a powerful distribution-free…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Mélanie Gaillochet , Christian Desrosiers , Hervé Lombaert

Compared to natural images, medical images usually show stronger visual patterns and therefore this adds flexibility and elasticity to resource-limited clinical applications by injecting proper priors into neural networks. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Hang Zhang , Rongguang Wang , Jinwei Zhang , Dongdong Liu , Chao Li , Jiahao Li

Deep learning methods for unsupervised registration often rely on objectives that assume a uniform noise level across the spatial domain (e.g. mean-squared error loss), but noise distributions are often heteroscedastic and input-dependent…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Xiaoran Zhang , Daniel H. Pak , Shawn S. Ahn , Xiaoxiao Li , Chenyu You , Lawrence H. Staib , Albert J. Sinusas , Alex Wong , James S. Duncan

Interactive image segmentation aims at segmenting a target region through a way of human-computer interaction. Recent works based on deep learning have achieved excellent performance, while most of them focus on improving the accuracy of…

Computer Vision and Pattern Recognition · Computer Science 2022-10-21 Yuying Hao , Yi Liu , Juncai Peng , Haoyi Xiong , Guowei Chen , Shiyu Tang , Zeyu Chen , Baohua Lai

Statistical shape modeling (SSM) directly from 3D medical images is an underutilized tool for detecting pathology, diagnosing disease, and conducting population-level morphology analysis. Deep learning frameworks have increased the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-17 Jadie Adams , Shireen Elhabian

Understanding how anatomical shapes evolve in response to developmental covariates and quantifying their spatially varying uncertainties is critical in healthcare research. Existing approaches typically rely on global time-warping…

In this paper, we consider the coefficient-based regularized distribution regression which aims to regress from probability measures to real-valued responses over a reproducing kernel Hilbert space (RKHS), where the regularization is put on…

Machine Learning · Statistics 2022-08-29 Yuan Mao , Lei Shi , Zheng-Chu Guo

A fundamental assumption of most machine learning algorithms is that the training and test data are drawn from the same underlying distribution. However, this assumption is violated in almost all practical applications: machine learning…

Machine Learning · Computer Science 2021-12-02 Marvin Zhang , Henrik Marklund , Nikita Dhawan , Abhishek Gupta , Sergey Levine , Chelsea Finn

In medical image segmentation, it is often necessary to collect opinions from multiple experts to make the final decision. This clinical routine helps to mitigate individual bias. But when data is multiply annotated, standard deep learning…

Image and Video Processing · Electrical Eng. & Systems 2022-12-02 Junde Wu , Huihui Fang , Yehui Yang , Yuanpei Liu , Jing Gao , Lixin Duan , Weihua Yang , Yanwu Xu

Objective:This study introduces a residual error-shifting mechanism that drastically reduces sampling steps while preserving critical anatomical details, thus accelerating MRI reconstruction. Approach:We propose a novel diffusion-based SR…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Mojtaba Safari , Shansong Wang , Zach Eidex , Qiang Li , Erik H. Middlebrooks , David S. Yu , Xiaofeng Yang

Effective training of deep image segmentation models is challenging due to the need for abundant, high-quality annotations. Generating annotations is laborious and time-consuming for human experts, especially in medical image segmentation.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Vikas Dwivedi , Balaji Srinivasan , Ganapathy Krishnamurthi

Modern deep neural networks achieved remarkable progress in medical image segmentation tasks. However, it has recently been observed that they tend to produce overconfident estimates, even in situations of high uncertainty, leading to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-05 Agostina Larrazabal , Cesar Martinez , Jose Dolz , Enzo Ferrante

Robustness and generalizability in medical image segmentation are often hindered by scarcity and limited diversity of training data, which stands in contrast to the variability encountered during inference. While conventional strategies --…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Yimu Pan , Sitao Zhang , Alison D. Gernand , Jeffery A. Goldstein , James Z. Wang