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The integration of Large Language Models (LLMs) into clinical decision support is critically obstructed by their opaque and often unreliable reasoning. In the high-stakes domain of healthcare, correct answers alone are insufficient;…

Artificial Intelligence · Computer Science 2026-04-21 Chen Zhan , Xiaoyu Tan , Gengchen Ma , Yu-Jie Xiong , Xiaoyan Jiang , Xihe Qiu

Learning analytics systems increasingly integrate large language models (LLMs) to provide adaptive scaffolding in complex learning environments, yet personalization is often driven by global instructional choices rather than principled…

Human-Computer Interaction · Computer Science 2026-05-07 Fatma Betul Gures , Tanya Nazaretsky , Tanja Kaser

Sequential recommender systems have achieved significant success in modeling temporal user behavior but remain limited in capturing rich user semantics beyond interaction patterns. Large Language Models (LLMs) present opportunities to…

Importance: We introduce a novel Retrieval Augmented Generation (RAG)-Large Language Model (LLM) framework as a Clinical Decision Support Systems (CDSS) to support safe medication prescription. Objective: To evaluate the efficacy of…

Accurate time series prediction is challenging due to the inherent nonlinearity and sensitivity to initial conditions. We propose a novel approach that enhances neural network predictions through differential learning, which involves…

Machine Learning · Computer Science 2025-03-11 Akash Yadav , Eulalia Nualart

Large language models (LLMs) have demonstrated impressive performance across various domains. However, for clinical diagnosis, higher expectations are required for LLM's reliability and sensitivity: thinking like physicians and remaining…

Computation and Language · Computer Science 2025-04-21 Chenwei Yan , Xiangling Fu , Yuxuan Xiong , Tianyi Wang , Siu Cheung Hui , Ji Wu , Xien Liu

In this paper, we present a novel diagnostic framework that integrates Knowledge Graphs (KGs) and Large Language Models (LLMs) to support system diagnostics in high-reliability systems such as nuclear power plants. Traditional diagnostic…

Artificial Intelligence · Computer Science 2025-09-01 Saman Marandi , Yu-Shu Hu , Mohammad Modarres

Multimodal Large Language Models (LLMs) hold promise for biomedical reasoning, but current benchmarks fail to capture the complexity of real-world clinical workflows. Existing evaluations primarily assess unimodal, decontextualized…

Recent advancements in medical Large Language Models (LLMs) have showcased their powerful reasoning and diagnostic capabilities. Despite their success, current unified multimodal medical LLMs face limitations in knowledge update costs,…

Computation and Language · Computer Science 2025-06-25 Yucheng Zhou , Lingran Song , Jianbing Shen

Large language models (LLMs) can learn vast amounts of knowledge from diverse domains during pre-training. However, long-tail knowledge from specialized domains is often scarce and underrepresented, rarely appearing in the models'…

Computation and Language · Computer Science 2025-02-11 Shuyang Yu , Runxue Bao , Parminder Bhatia , Taha Kass-Hout , Jiayu Zhou , Cao Xiao

Multi-Agent Pathfinding (MAPF) is a core challenge in multi-agent systems. Existing learning-based MAPF methods often struggle with scalability, particularly when addressing complex scenarios that are prone to deadlocks. To address these…

Multiagent Systems · Computer Science 2025-03-04 Seungbae Seo , Junghwan Kim , Minjeong Shin , Bongwon Suh

Therapy recommendation for chronic patients with multimorbidity is challenging due to risks of treatment conflicts. Existing decision support systems face scalability limitations. Inspired by the way in which general practitioners (GP)…

Artificial Intelligence · Computer Science 2025-07-16 Yicong Wu , Ting Chen , Irit Hochberg , Zhoujian Sun , Ruth Edry , Zhengxing Huang , Mor Peleg

Foundation models are becoming valuable tools in medicine. Yet despite their promise, the best way to leverage Large Language Models (LLMs) in complex medical tasks remains an open question. We introduce a novel multi-agent framework, named…

Computation and Language · Computer Science 2024-10-31 Yubin Kim , Chanwoo Park , Hyewon Jeong , Yik Siu Chan , Xuhai Xu , Daniel McDuff , Hyeonhoon Lee , Marzyeh Ghassemi , Cynthia Breazeal , Hae Won Park

Clinical trials are critical for advancing medical treatments but remain prohibitively expensive and time-consuming. Accurate prediction of clinical trial outcomes can significantly reduce research and development costs and accelerate drug…

Machine Learning · Computer Science 2025-06-06 Fengze Liu , Haoyu Wang , Joonhyuk Cho , Dan Roth , Andrew W. Lo

This paper presents an innovative large language model (LLM) agent framework for enhancing diagnostic accuracy in simulated clinical environments using the AgentClinic benchmark. The proposed automatic correction enables doctor agents to…

Artificial Intelligence · Computer Science 2024-10-15 Abhishek Dutta , Yen-Che Hsiao

Building effective clinical decision support systems requires the synthesis of complex heterogeneous multimodal data. Such modalities include temporal electronic health records data, medical images, radiology reports, and clinical notes.…

Artificial Intelligence · Computer Science 2026-05-12 Baraa Al Jorf , Farah E. Shamout

Label Distribution Learning (LDL) aims to characterize the polysemy of an instance by building a set of descriptive degrees corresponding to the instance. In recent years, researchers seek to model to obtain an accurate label distribution…

Machine Learning · Computer Science 2025-04-03 Pu Wang , Yu Zhang , Zhuoran Zheng

Making accurate motion prediction of surrounding agents such as pedestrians and vehicles is a critical task when robots are trying to perform autonomous navigation tasks. Recent research on multi-modal trajectory prediction, including…

Computer Vision and Pattern Recognition · Computer Science 2020-10-16 YingQiao Wang

Diffusion large language models (DLLMs) have emerged as an alternative to autoregressive (AR) decoding with appealing efficiency and modeling properties, yet their implications for agentic multi-step decision making remain underexplored. We…

Traffic forecasting is crucial for intelligent transportation systems. It has experienced significant advancements thanks to the power of deep learning in capturing latent patterns of traffic data. However, recent deep-learning…

Machine Learning · Computer Science 2026-01-19 Xusen Guo , Qiming Zhang , Junyue Jiang , Mingxing Peng , Meixin Zhu , Hao , Yang