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The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Li Shen , Laurie R. Margolies , Joseph H. Rothstein , Eugene Fluder , Russell B. McBride , Weiva Sieh

Breast cancer is the most frequently diagnosed human cancer in the United States at present. Early detection is crucial for its successful treatment. X-ray mammography and digital breast tomosynthesis are currently the main methods for…

Full Field Digital Mammograms (FFDMs) and Digital Breast Tomosynthesis (DBT) are the two most widely used imaging modalities for breast cancer screening. Although DBT has increased cancer detection compared to FFDM, its widespread adoption…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Umang Sharma , Jungkyu Park , Laura Heacock , Sumit Chopra , Krzysztof Geras

The scarcity of publicly available medical imaging data limits the development of effective AI models. This work proposes a memory-efficient patch-wise denoising diffusion probabilistic model (DDPM) for generating synthetic medical images,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Kathrin Khadra , Utku Türkbey

Deep-learning-based object detection methods show promise for improving screening mammography, but high rates of false positives can hinder their effectiveness in clinical practice. To reduce false positives, we identify three challenges:…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Yen Nhi Truong Vu , Dan Guo , Ahmed Taha , Jason Su , Thomas Paul Matthews

Generative artificial intelligence (AI) has been playing an important role in various domains. Leveraging its high capability to generate high-fidelity and diverse synthetic data, generative AI is widely applied in diagnostic tasks, such as…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Yifan Jiang , Ahmad Shariftabrizi , Venkata SK. Manem

This letter introduces a dual application of denoising diffusion probabilistic model (DDPM)-based channel estimation algorithm integrating data denoising and augmentation. Denoising addresses the severe noise in raw signals at pilot…

Signal Processing · Electrical Eng. & Systems 2025-10-06 Yupeng Li , Ruhao Zhang , Yitong Liu , Chunju Shao , Jing Jin , Shijian Gao

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

We propose a novel unpaired image-to-image translation method that uses denoising diffusion probabilistic models without requiring adversarial training. Our method, UNpaired Image Translation with Denoising Diffusion Probabilistic Models…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Hiroshi Sasaki , Chris G. Willcocks , Toby P. Breckon

We investigate whether synthetic images generated by diffusion models can enhance multi-label classification of protein subcellular localization. Specifically, we implement a simplified class-conditional denoising diffusion probabilistic…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Sylvey Lin , Zhi-Yi Cao

Visual defect detection in industrial glass manufacturing remains a critical challenge due to the low frequency of defective products, leading to imbalanced datasets that limit the performance of deep learning models and computer vision…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Sajjad Rezvani Boroujeni , Hossein Abedi , Tom Bush

State-of-the-art deep learning methods for image processing are evolving into increasingly complex meta-architectures with a growing number of modules. Among them, region-based fully convolutional networks (R-FCN) and deformable…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Stephen Morrell , Zbigniew Wojna , Can Son Khoo , Sebastien Ourselin , Juan Eugenio Iglesias

Dynamic Contrast Enhanced-Magnetic Resonance Imaging (DCE-MRI) is widely used to complement ultrasound examinations and x-ray mammography during the early detection and diagnosis of breast cancer. However, images generated by various MRI…

Image and Video Processing · Electrical Eng. & Systems 2021-06-18 Gourav Modanwal , Adithya Vellal , Maciej A. Mazurowski

Digital Breast Tomosynthesis (DBT) provides an insight into the fine details of normal fibroglandular tissues and abnormal lesions by reconstructing a pseudo-3D image of the breast. In this respect, DBT overcomes a major limitation of…

Computer Vision and Pattern Recognition · Computer Science 2013-07-24 Guang Yang , John H. Hipwell , David J. Hawkes , Simon R. Arridge

We propose a novel and unified method, measurement-conditioned denoising diffusion probabilistic model (MC-DDPM), for under-sampled medical image reconstruction based on DDPM. Different from previous works, MC-DDPM is defined in measurement…

Image and Video Processing · Electrical Eng. & Systems 2022-03-09 Yutong Xie , Quanzheng Li

Our objective is to show the feasibility of using simulated mammograms to detect mammographically-occult (MO) cancer in women with dense breasts and a normal screening mammogram who could be triaged for additional screening with magnetic…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Juhun Lee , Robert M. Nishikawa

Hyperspectral images (HSI) have a large amount of spectral information reflecting the characteristics of matter, while their spatial resolution is low due to the limitations of imaging technology. Complementary to this are multispectral…

Image and Video Processing · Electrical Eng. & Systems 2023-07-10 Shuaikai Shi , Lijun Zhang , Jie Chen

Breast cancer is the most common cancers and early detection from mammography screening is crucial in improving patient outcomes. Assessing mammographic breast density is clinically important as the denser breasts have higher risk and are…

Image and Video Processing · Electrical Eng. & Systems 2022-06-27 Charles Lu , Ken Chang , Praveer Singh , Jayashree Kalpathy-Cramer

Recent advances in imaging and high-performance computing have made it possible to image the entire human brain at the cellular level. This is the basis to study the multi-scale architecture of the brain regarding its subdivision into brain…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Jan-Oliver Kropp , Christian Schiffer , Katrin Amunts , Timo Dickscheid

Deep learning techniques for anatomical landmark localization (ALL) have shown great success, but their reliance on large annotated datasets remains a problem due to the tedious and costly nature of medical data acquisition and annotation.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Arnela Hadzic , Lea Bogensperger , Simon Johannes Joham , Martin Urschler