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Retrosynthesis is a technique to plan the chemical synthesis of organic molecules, for example drugs, agro- and fine chemicals. In retrosynthesis, a search tree is built by analysing molecules recursively and dissecting them into simpler…

Artificial Intelligence · Computer Science 2017-02-02 Marwin Segler , Mike Preuß , Mark P. Waller

Multi-agent systems (MAS) are widely prevalent and crucially important in numerous real-world applications, where multiple agents must make decisions to achieve their objectives in a shared environment. Despite their ubiquity, the…

Multiagent Systems · Computer Science 2024-07-04 Dom Huh , Prasant Mohapatra

Retrosynthesis, the process of breaking down a target molecule into simpler precursors through a series of valid reactions, stands at the core of organic chemistry and drug development. Although recent machine learning (ML) research has…

Artificial Intelligence · Computer Science 2026-05-12 Haorui Wang , Jeff Guo , Lingkai Kong , Rampi Ramprasad , Philippe Schwaller , Yuanqi Du , Chao Zhang

In question-answering (QA) systems, Retrieval-Augmented Generation (RAG) has become pivotal in enhancing response accuracy and reducing hallucination issues. The architecture of RAG systems varies significantly, encompassing single-round…

Computation and Language · Computer Science 2025-08-05 Yiqun Chen , Erhan Zhang , Lingyong Yan , Shuaiqiang Wang , Jizhou Huang , Dawei Yin , Jiaxin Mao

Retrosynthesis planning enables the discovery of viable synthetic routes for target molecules, playing a crucial role in domains like drug discovery and materials design. Multi-step retrosynthetic planning remains computationally…

Artificial Intelligence · Computer Science 2025-09-29 Xiaozhuang Song , Xuanhao Pan , Xinjian Zhao , Hangting Ye , Shufei Zhang , Jian Tang , Tianshu Yu

Multi-Agent Reinforcement Learning can lead to the development of collaborative agent behaviors that show similarities with organizational concepts. Pushing forward this perspective, we introduce a novel framework that explicitly…

Artificial Intelligence · Computer Science 2025-04-01 Julien Soulé , Jean-Paul Jamont , Michel Occello , Louis-Marie Traonouez , Paul Théron

In Multiagent Path Finding (MAPF), the goal is to compute efficient, collision-free paths for multiple agents navigating a network from their sources to targets, minimizing the schedule's makespan-the total time until all agents reach their…

Multiagent Systems · Computer Science 2025-08-07 Foivos Fioravantes , Dušan Knop , Nikolaos Melissinos , Michal Opler

Reinforcement learning is a promising approach to learning control policies for performing complex multi-agent robotics tasks. However, a policy learned in simulation often fails to guarantee even simple safety properties such as obstacle…

Systems and Control · Electrical Eng. & Systems 2020-01-01 Wenbo Zhang , Osbert Bastani , Vijay Kumar

Multi-agent path finding (MAPF) is the problem of planning conflict-free paths from the designated start locations to goal positions for multiple agents. It underlies a variety of real-world tasks, including multi-robot coordination,…

Artificial Intelligence · Computer Science 2025-09-09 Zhanjiang Yang , Yang Shen , Yueming Li , Meng Li , Lijun Sun

Clinical decision-making requires nuanced reasoning over heterogeneous evidence and traceable justifications. While recent LLM multi-agent systems (MAS) show promise, they largely optimise for outcome accuracy while overlooking…

Artificial Intelligence · Computer Science 2026-02-17 Chaeeun Lee , T. Michael Yates , Pasquale Minervini , T. Ian Simpson

Multi-Agent Path Finding (MAPF) is a fundamental problem in robotics, requiring the computation of collision-free paths for multiple agents moving from their respective start to goal positions. Coordinating multiple agents in a shared…

Robotics · Computer Science 2024-12-25 Jinhao Liang , Jacob K. Christopher , Sven Koenig , Ferdinando Fioretto

Large language model-based (LLM-based) multi-agent systems (MAS) are increasingly used to extend agentic problem solving via role specialization and collaboration. MAS workflows can be naturally modeled as directed computation graphs, where…

Computation and Language · Computer Science 2026-05-21 Yang Liu , Jinxuan Cai , Yishen Li , Qi Meng , Zedi Liu , Xin Li , Chen Qian , Chuan Shi , Cheng Yang

The multi-agent pathfinding (MAPF) problem seeks collision-free paths for a team of agents from their current positions to their pre-set goals in a known environment, and is an essential problem found at the core of many logistics,…

Robotics · Computer Science 2023-10-13 Chengyang He , Tianze Yang , Tanishq Duhan , Yutong Wang , Guillaume Sartoretti

Efficient path planning for unmanned aerial vehicles (UAVs) is crucial in remote sensing and information collection. As task scales expand, the cooperative deployment of multiple UAVs significantly improves information collection…

Multiagent Systems · Computer Science 2025-03-06 Zilin Zhao , Chishui Chen , Haotian Shi , Jiale Chen , Xuanlin Yue , Zhejian Yang , Yang Liu

Machine learning has been widely used to optimize complex engineering workflows across numerous domains. In integrated circuit design, modern flows (e.g., register-transfer level to physical layout) involve extensive configuration via…

Artificial Intelligence · Computer Science 2026-05-01 Amur Ghose , Andrew B. Kahng , Sayak Kundu , Zhiang Wang

We present MOSS, a multi-objective optimization framework for constructing stable sets of decision rules. MOSS incorporates three important criteria for interpretability: sparsity, accuracy, and stability, into a single multi-objective…

Optimization and Control · Mathematics 2025-07-31 Brian Liu , Rahul Mazumder

Therapy recommendation for chronic patients with multimorbidity is challenging due to risks of treatment conflicts. Existing decision support systems face scalability limitations. Inspired by the way in which general practitioners (GP)…

Artificial Intelligence · Computer Science 2025-07-16 Yicong Wu , Ting Chen , Irit Hochberg , Zhoujian Sun , Ruth Edry , Zhengxing Huang , Mor Peleg

Remote sensing image interpretation plays a critical role in environmental monitoring, urban planning, and disaster assessment. However, acquiring high-quality labeled data is often costly and time-consuming. To address this challenge, we…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Tong Wang , Guanzhou Chen , Xiaodong Zhang , Chenxi Liu , Jiaqi Wang , Xiaoliang Tan , Wenchao Guo , Qingyuan Yang , Kaiqi Zhang

We present Scalable Multi-Agent Realistic Testbed (SMART), a realistic and efficient software tool for evaluating Multi-Agent Path Finding (MAPF) algorithms. MAPF focuses on planning collision-free paths for a group of robots. While…

We investigate multi-agent navigation tasks, where multiple agents need to reach initially unassigned goals in a limited time. Classical planning-based methods suffer from expensive computation overhead at each step and offer limited…

Machine Learning · Computer Science 2024-12-03 Xinyi Yang , Xinting Yang , Chao Yu , Jiayu Chen , Wenbo Ding , Huazhong Yang , Yu Wang
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