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Coalescent models of bifurcating genealogies are used to infer evolutionary parameters from molecular data. However, there are many situations where bifurcating genealogies do not accurately reflect the true underlying ancestral history of…

Probability · Mathematics 2025-06-13 Julie Zhang , Noah A. Rosenberg , Julia A. Palacios

Evolution is a process that is influenced by various environmental factors, e.g. the interactions between different species, genes, and biogeographical properties. Hence, it is interesting to study the combined evolutionary history of…

Quantitative Methods · Quantitative Biology 2013-08-02 Nicolas Wieseke , Matthias Bernt , Martin Middendorf

Here we introduce researchers in algebraic biology to the exciting new field of cophylogenetics. Cophylogenetics is the study of concomitantly evolving organisms (or genes), such as host and parasite species. Thus the natural objects of…

Populations and Evolution · Quantitative Biology 2009-02-03 Peter Huggins , Megan Owen , Ruriko Yoshida

We introduce regenerative tree growth processes as consistent families of random trees with n labelled leaves, n>=1, with a regenerative property at branch points. This framework includes growth processes for exchangeably labelled Markov…

Probability · Mathematics 2013-09-30 Jim Pitman , Douglas Rizzolo , Matthias Winkel

Phylogenetic networks are generalizations of phylogenetic trees that allow the representation of reticulation events such as horizontal gene transfer or hybridization, and can also represent uncertainty in inference. A subclass of these,…

Populations and Evolution · Quantitative Biology 2019-10-15 Mareike Fischer , Andrew Francis

This paper demonstrates that every ultrametric space is homeomorphic to a clade space of a pruned tree, i.e., a subspace of a tree's canopy. Furthermore, it characterizes several topological properties of ultrametrizable spaces through the…

General Topology · Mathematics 2024-08-01 Itamar Bellaïche

Phylogenetic networks are a generalization of phylogenetic trees that are used to represent non-tree-like evolutionary histories that arise in organisms such as plants and bacteria, or uncertainty in evolutionary histories. An…

Populations and Evolution · Quantitative Biology 2017-12-08 Andrew Francis , Katharina Huber , Vincent Moulton

The phylogenetic tree space introduced by Billera, Holmes, and Vogtmann (BHV tree space) is a CAT(0) continuous space that represents trees with edge weights with an intrinsic geodesic distance measure. The geodesic distance measure unique…

Quantitative Methods · Quantitative Biology 2021-10-29 Yingying Ren , Sihan Zha , Jingwen Bi , José A. Sanchez , Cara Monical , Michelle Delcourt , Rosemary K. Guzman , Ruth Davidson

We show that the homology of ordered configuration spaces of finite trees with loops is torsion free. We introduce configuration spaces with sinks, which allow for taking quotients of the base space. Furthermore, we give a concrete…

Algebraic Topology · Mathematics 2018-05-02 Safia Chettih , Daniel Lütgehetmann

Tree alignment graphs (TAGs) provide an intuitive data structure for storing phylogenetic trees that exhibits the relationships of the individual input trees and can potentially account for nested taxonomic relationships. This paper…

Data Structures and Algorithms · Computer Science 2015-03-16 Ruchi Chaudhary , David Fernandez-Baca , J. Gordon Burleigh

Suppose N is a phylogenetic network indicating a complicated relationship among individuals and taxa. Often of interest is a much simpler network, for example, a species tree T, that summarizes the most fundamental relationships. The…

Populations and Evolution · Quantitative Biology 2015-01-30 Stephen J. Willson

Cancers follow a clonal Darwinian evolution, with fitter subclones replacing more quiescent cells, ultimately giving rise to macroscopic disease. High-throughput genomics provides the opportunity to investigate these processes and determine…

Quantitative Methods · Quantitative Biology 2014-10-07 Sakellarios Zairis , Hossein Khiabanian , Andrew J. Blumberg , Raul Rabadan

The relative importance of the intrinsic and extrinsic factors determining the variety of geometric shapes exhibited by dendritic trees remains unclear. This question was addressed by developing a model of the growth of dendritic trees…

Neurons and Cognition · Quantitative Biology 2007-05-23 Artur Luczak

We define and give explicit construction of the universal tree-graded space with a given collection of pieces. We apply that to proving uniqueness of asymptotic cones of relatively hyperbolic groups whose peripheral subgroups have unique…

Group Theory · Mathematics 2011-03-22 Denis Osin , Mark Sapir

A model of genomic sequence evolution on a species tree should include not only a sequence substitution process, but also a coalescent process, since different sites may evolve on different gene trees due to incomplete lineage sorting.…

Populations and Evolution · Quantitative Biology 2023-03-15 Elizabeth A. Allman , Colby Long , John A. Rhodes

Given a finite group G and a natural number n, we study the structure of the complex of nested sets of the associated Dowling lattice Q(G) and of its subposet of the G-symmetric partitions Q_G which was recently introduced by Hultman…

Combinatorics · Mathematics 2007-05-23 Emanuele Delucchi

Using the wedge sum of metric spaces, for all compact metrizable spaces, we construct a topological embedding of the compact metrizable space into the set of all metric trees in the Gromov--Hausdorff space with finite prescribed values. As…

Metric Geometry · Mathematics 2021-12-13 Yoshito Ishiki

It was recently observed by de Vienne et al. that a simple square root transformation of distances between taxa on a phylogenetic tree allowed for an embedding of the taxa into Euclidean space. While the justification for this was based on…

Populations and Evolution · Quantitative Biology 2016-05-04 Mark Layer , John A. Rhodes

Phylogenetic networks are a generalisation of phylogenetic trees that allow for more complex evolutionary histories that include hybridisation-like processes. It is of considerable interest whether a network can be considered `tree-like' or…

Populations and Evolution · Quantitative Biology 2017-11-21 Michael Hendriksen

Metrics on rooted phylogenetic trees are integral to a number of areas of phylogenetic analysis. Cluster-similarity metrics have recently been introduced in order to limit skew in the distribution of distances, and to ensure that trees in…

Populations and Evolution · Quantitative Biology 2019-11-26 Michael Hendriksen , Andrew Francis