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Multimodal magnetic resonance imaging (MRI) constitutes the first line of investigation for clinicians in the care of brain tumors, providing crucial insights for surgery planning, treatment monitoring, and biomarker identification.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Lucas Robinet , Ahmad Berjaoui , Elizabeth Cohen-Jonathan Moyal

Despite the recent success of Multimodal Large Language Models (MLLMs), existing approaches predominantly assume the availability of multiple modalities during training and inference. In practice, multimodal data is often incomplete because…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Divyam Madaan , Sumit Chopra , Kyunghyun Cho

The use of diverse modalities, such as omics, medical images, and clinical data can not only improve the performance of prognostic models but also deepen an understanding of disease mechanisms and facilitate the development of novel…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Maria Boyko , Aleksandra Beliaeva , Dmitriy Kornilov , Alexander Bernstein , Maxim Sharaev

Multimodal approaches that integrate histology and genomics hold strong potential for precision oncology. However, phenotypic and genotypic heterogeneity limits the quality of intra-modal representations and hinders effective inter-modal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Yupei Zhang , Yating Huang , Wanming Hu , Lequan Yu , Hujun Yin , Chao Li

Multimodal models integrating natural language and visual information have substantially improved generalization of representation models. However, their effectiveness significantly declines in real-world situations where certain modalities…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Jiajun Chen , Sai Cheng , Yutao Yuan , Yirui Zhang , Haitao Yuan , Peng Peng , Yi Zhong

Contrastive learning based vision-language joint pre-training has emerged as a successful representation learning strategy. In this paper, we present a prototype representation learning framework incorporating both global and local…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Pujin Cheng , Li Lin , Junyan Lyu , Yijin Huang , Wenhan Luo , Xiaoying Tang

Multimodal learning typically relies on the assumption that all modalities are fully available during both the training and inference phases. However, in real-world scenarios, consistently acquiring complete multimodal data presents…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Donggeun Kim , Taesup Kim

Multimodal magnetic resonance imaging (MRI) provides complementary information for sub-region analysis of brain tumors. Plenty of methods have been proposed for automatic brain tumor segmentation using four common MRI modalities and…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Hong Liu , Dong Wei , Donghuan Lu , Jinghan Sun , Liansheng Wang , Yefeng Zheng

Medical diagnosis requires the effective synthesis of visual manifestations and clinical metadata. However, existing methods often treat metadata as isolated tags, failing to exploit the rich semantic knowledge embedded in clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Yiqing Wang , Chunming He , Ming-Chen Lu , Mercy Pawar , Leslie Niziol , Maria Woodward , Sina Farsiu

Multimodal data provides heterogeneous information for a holistic understanding of the tumor microenvironment. However, existing AI models often struggle to harness the rich information within multimodal data and extract poorly…

Machine Learning · Computer Science 2025-09-17 Huajun Zhou , Fengtao Zhou , Jiabo Ma , Yingxue Xu , Xi Wang , Xiuming Zhang , Li Liang , Zhenhui Li , Hao Chen

Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which reduces their usefulness in clinical settings. Prototype learning presents a potential solution,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Shuo Jiang , Zhuwen Chen , Liaoman Xu , Yanming Zhu , Changmiao Wang , Jiong Zhang , Feiwei Qin , Yifei Chen , Zhu Zhu

Multimodal learning has demonstrated incredible successes by integrating diverse data sources, yet it often relies on the availability of all modalities - an assumption that rarely holds in real-world applications. Pretrained multimodal…

Machine Learning · Computer Science 2025-04-21 Duy A. Nguyen , Quan Huu Do , Khoa D. Doan , Minh N. Do

Substantial advances in multi-modal Artificial Intelligence (AI) facilitate the combination of diverse medical modalities to achieve holistic health assessments. We present COMPRER , a novel multi-modal, multi-objective pretraining…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Guy Lutsker , Hagai Rossman , Nastya Godiva , Eran Segal

Multimodal pathological images are usually in clinical diagnosis, but computer vision-based multimodal image-assisted diagnosis faces challenges with modality fusion, especially in the absence of expert-annotated data. To achieve the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Qinghua Lin , Guang-Hai Liu , Zuoyong Li , Yang Li , Yuting Jiang , Xiang Wu

Self-supervised learning has greatly facilitated medical image analysis by suppressing the training data requirement for real-world applications. Current paradigms predominantly rely on self-supervision within uni-modal image data, thereby…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Shaohao Rui , Lingzhi Chen , Zhenyu Tang , Lilong Wang , Mianxin Liu , Shaoting Zhang , Xiaosong Wang

Integrating the different data modalities of cancer patients can significantly improve the predictive performance of patient survival. However, most existing methods ignore the simultaneous utilization of rich semantic features at different…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Liangrui Pan , Yijun Peng , Yan Li , Yiyi Liang , Liwen Xu , Qingchun Liang , Shaoliang Peng

Many healthcare applications are inherently multimodal, involving several physiological signals. As sensors for these signals become more common, improving machine learning methods for multimodal healthcare data is crucial. Pretraining…

Machine Learning · Computer Science 2024-10-23 Ching Fang , Christopher Sandino , Behrooz Mahasseni , Juri Minxha , Hadi Pouransari , Erdrin Azemi , Ali Moin , Ellen Zippi

Recently, deep learning models have shown the potential to predict breast cancer risk and enable targeted screening strategies, but current models do not consider the change in the breast over time. In this paper, we present a new method,…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Hyeonsoo Lee , Junha Kim , Eunkyung Park , Minjeong Kim , Taesoo Kim , Thijs Kooi

Recent advancements in multimodal pre-training models have significantly advanced computational pathology. However, current approaches predominantly rely on visual-language models, which may impose limitations from a molecular perspective…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Minghao Han , Dingkang Yang , Jiabei Cheng , Xukun Zhang , Linhao Qu , Zizhi Chen , Lihua Zhang

Self-supervised pretraining attempts to enhance model performance by obtaining effective features from unlabeled data, and has demonstrated its effectiveness in the field of histopathology images. Despite its success, few works concentrate…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Zhiyun Song , Penghui Du , Junpeng Yan , Kailu Li , Jianzhong Shou , Maode Lai , Yubo Fan , Yan Xu
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