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Imputation of missing values is a strategy for handling non-responses in surveys or data loss in measurement processes, which may be more effective than ignoring them. When the variable represents a count, the literature dealing with this…

Applications · Statistics 2020-07-31 Gilma Hernández-Herrera , Albert Navarro , David Moriña

In this paper, we study the problem of computing a Principal Component Analysis of data affected by Poisson noise. We assume samples are drawn from independent Poisson distributions. We want to estimate principle components of a fixed…

Methodology · Statistics 2021-05-25 Toby Kenney , Tianshu Huang , Hong Gu

Gaussian graphical models are often used to infer gene networks based on microarray expression data. Many scientists, however, have begun using high-throughput sequencing technologies to measure gene expression. As the resulting…

Applications · Statistics 2012-05-30 Genevera I. Allen , Zhandong Liu

The elastic net penalty is frequently employed in high-dimensional statistics for parameter regression and variable selection. It is particularly beneficial compared to lasso when the number of predictors greatly surpasses the number of…

Machine Learning · Statistics 2024-12-06 Yanyun Ding , Zhenghua Yao , Peili Li , Yunhai Xiao

Event counts are response variables with non-negative integer values representing the number of times that an event occurs within a fixed domain such as a time interval, a geographical area or a cell of a contingency table. Analysis of…

Qualifying gene and isoform expression is one of the primary tasks for RNA-Seq experiments. Given a sequence of counts representing numbers of reads mapped to different positions (exons and junctions) of isoforms, methods based on Poisson…

Applications · Statistics 2014-10-27 Jun Li , Hui Jiang

In regression analysis of counts, a lack of simple and efficient algorithms for posterior computation has made Bayesian approaches appear unattractive and thus underdeveloped. We propose a lognormal and gamma mixed negative binomial (NB)…

Applications · Statistics 2012-07-03 Mingyuan Zhou , Lingbo Li , David Dunson , Lawrence Carin

Bayesian multinomial logistic-normal (MLN) models are popular for the analysis of sequence count data (e.g., microbiome or gene expression data) due to their ability to model multivariate count data with complex covariance structure.…

In the analysis of count data often the equidispersion assumption is not suitable, hence the Poisson regression model is inappropriate. As a generalization of the Poisson distribution, the COM-Poisson distribution can deal with under-,…

Neural networks capable of accurate, input-conditional uncertainty representation are essential for real-world AI systems. Deep ensembles of Gaussian networks have proven highly effective for continuous regression due to their ability to…

Machine Learning · Computer Science 2025-10-02 Spencer Young , Porter Jenkins , Longchao Da , Jeff Dotson , Hua Wei

Poisson-like behavior for event count data is ubiquitous in nature. At the same time, differencing of such counts arises in the course of data processing in a variety of areas of application. As a result, the Skellam distribution -- defined…

Probability · Mathematics 2018-04-04 H. L. Gan , Eric D. Kolaczyk

Multiple systems estimation using a Poisson loglinear model is a standard approach to quantifying hidden populations where data sources are based on lists of known cases. Information criteria are often used for selecting between the large…

Methodology · Statistics 2023-11-23 Bernard W. Silverman , Lax Chan , Kyle Vincent

The latent position network model (LPM) is a popular approach for the statistical analysis of network data. A central aspect of this model is that it assigns nodes to random positions in a latent space, such that the probability of an…

Methodology · Statistics 2026-02-02 Chaoyi Lu , Riccardo Rastelli , Nial Friel

Trial-to-trial variability of neural responses has been linked to important aspects of neural computation and is essential for understanding how neuronal populations respond. While current overdispersion models treat each neuron's gain as…

Quantitative Methods · Quantitative Biology 2026-05-11 Skyler Thomas , Brandon J. Zhu , Kathleen E. Cullen , Adam S. Charles

While several Gaussian mixture models-based biclustering approaches currently exist in the literature for continuous data, approaches to handle discrete data have not been well researched. A multivariate Poisson-lognormal (MPLN) model-based…

Methodology · Statistics 2025-03-13 Caitlin Kral , Evan Chance , Ryan Browne , Sanjeena Subedi

Medical machine learning algorithms are typically evaluated based on accuracy vs. a clinician-defined ground truth, a reasonable initial choice since trained clinicians are usually better classifiers than ML models. However, this metric…

Machine Learning · Computer Science 2024-05-21 Charles B. Delahunt , Courosh Mehanian , Matthew P. Horning

The edges in networks are not only binary, either present or absent, but also take weighted values in many scenarios (e.g., the number of emails between two users). The covariate-$p_0$ model has been proposed to model binary directed…

Statistics Theory · Mathematics 2021-07-24 MengXu , Qiuping Wang

Penalized generalized estimating equations with Elastic Net or L2-Smoothly Clipped Absolute Deviation penalization are proposed to simultaneously select the most important variables and estimate their effects for longitudinal Gaussian data…

Methodology · Statistics 2012-11-26 Adriaan Blommaert , Niel Hens , Philippe Beutels

To model recurrent interaction events in continuous time, an extension of the stochastic block model is proposed where every individual belongs to a latent group and interactions between two individuals follow a conditional inhomogeneous…

Methodology · Statistics 2023-08-30 Catherine Matias , Tabea Rebafka , Fanny Villers

The generalised linear model (GLM) is a very important tool for analysing real data in biology, sociology, agriculture, engineering and many other application domain where the relationship between the response and explanatory variables may…

Methodology · Statistics 2016-07-04 Abhik Ghosh , Ayanendranath Basu