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Large Language Models (LLMs) are increasingly deployed to automatically label and analyze educational dialogue at scale, yet current pipelines lack reliable ways to detect when models are wrong. We investigate whether reasoning generated by…

Accurate and interpretable prediction of estimated glomerular filtration rate (eGFR) is essential for managing chronic kidney disease (CKD) and supporting clinical decisions. Recent advances in Large Multimodal Models (LMMs) have shown…

Large Language Models (LLMs) demonstrate remarkable performance on a variety of natural language understanding (NLU) tasks, primarily due to their in-context learning ability. This ability could be applied to building babylike models, i.e.…

Large language models (LLMs) have emerged as promising tools for assisting in medical tasks, yet processing Electronic Health Records (EHRs) presents unique challenges due to their longitudinal nature. While LLMs' capabilities to perform…

Large language models (LLMs), typically designed as a function of next-word prediction, have excelled across extensive NLP tasks. Despite the generality, next-word prediction is often not an efficient formulation for many of the tasks,…

Pre-trained Large Language Models (LLMs) have revolutionized text processing, yet adapting Transformer-based neural networks to non-textual scientific modalities typically requires specialized architectures and extensive computational…

Pretrained large language models (LLMs) exhibit exceptional general language processing capabilities but come with significant demands on memory and computational resources. As a powerful compression technology, binarization can extremely…

Discharge communication is a critical yet underexplored component of patient care, where the goal shifts from diagnosis to education. While recent large language model (LLM) benchmarks emphasize in-visit diagnostic reasoning, they fail to…

Large language models (LLMs) are increasingly used to generate summaries from clinical notes. However, their ability to preserve essential diagnostic information remains underexplored, which could lead to serious risks for patient care.…

Large language models (LLMs) have shown remarkable capabilities in Natural Language Processing (NLP), especially in domains where labeled data is scarce or expensive, such as clinical domain. However, to unlock the clinical knowledge hidden…

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

The performance of Large Language Models (LLMs) on downstream tasks is fundamentally constrained by the capabilities acquired during pre-training. However, traditional benchmarks like MMLU often fail to reflect a base model's plasticity in…

Clinical notes are a rich source of information about patient state. However, using them to predict clinical events with machine learning models is challenging. They are very high dimensional, sparse and have complex structure. Furthermore,…

General-purpose Large Language Models (LLMs) are frequently fine-tuned through supervised fine-tuning (SFT) to enhance performance in specific domains. Better results can be achieved by distilling the chain-of-thought of a larger model at…

Clinical notes in electronic health records contain highly heterogeneous writing styles, including non-standard terminology or abbreviations. Using these notes in predictive modeling has traditionally required preprocessing (e.g. taking…

Recently, Large Language Models (LLMs) have gained significant traction in medical domain, especially in developing a QA systems to Medical QA systems for enhancing access to healthcare in low-resourced settings. This paper compares five…

Medical reasoning in large language models (LLMs) aims to emulate clinicians' diagnostic thinking, but current benchmarks such as MedQA-USMLE, MedMCQA, and PubMedQA often mix reasoning with factual recall. We address this by separating 11…

The deployment of large language models (LLMs) in real-world applications is increasingly limited by their high inference cost. While recent advances in dynamic token-level computation allocation attempt to improve efficiency by selectively…

Large language models (LLMs) are increasingly powering Text-to-SQL (Text2SQL) systems, enabling non-expert users to query industrial databases using natural language. While test-time scaling strategies have shown promise in LLM-based…

Background: Large language models (LLMs) have seen extraordinary advances with applications in clinical decision support. However, high-quality evidence is urgently needed on the potential and limitation of LLMs in providing accurate…