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Biological neural networks self-organize according to local synaptic modifications to produce stable computations. How modifications at the synaptic level give rise to such computations at the network level remains an open question.…

Neurons and Cognition · Quantitative Biology 2026-01-21 David Lipshutz , Robert J. Lipshutz

Hebbian and anti-Hebbian plasticity are widely observed in the biological brain, yet their theoretical understanding remains limited. In this work, we find that when a learning method is regularized with L2 weight decay, its learning signal…

Machine Learning · Computer Science 2025-12-02 David Koplow , Tomaso Poggio , Liu Ziyin

Topographic maps are a brain structure connecting pre-synpatic and post-synaptic brain regions. Topographic development is dependent on Hebbian-based plasticity mechanisms working in conjunction with spontaneous patterns of neural activity…

Neurons and Cognition · Quantitative Biology 2025-01-15 Nicholas Gale , Jennifer Rodger , Michael Small , Stephen Eglen

Biological neural networks are characterized by their high degree of plasticity, a core property that enables the remarkable adaptability of natural organisms. Importantly, this ability affects both the synaptic strength and the topology of…

Neural and Evolutionary Computing · Computer Science 2024-06-17 Erwan Plantec , Joachin W. Pedersen , Milton L. Montero , Eleni Nisioti , Sebastian Risi

Control policies in deep reinforcement learning are often implemented with fixed-capacity multilayer perceptrons trained by backpropagation, which lack structural plasticity and depend on global error signals. This paper introduces the…

Neural and Evolutionary Computing · Computer Science 2025-12-16 Yiyang Jia , Chengxu Zhou

Robust perception in brains is often attributed to high-dimensional population activity together with local plasticity mechanisms that reinforce recurring structure. In contrast, most modern image recognition systems are trained by error…

Neural and Evolutionary Computing · Computer Science 2026-03-10 Heng Zhang

Brain plasticity, also known as neuroplasticity, is a fundamental mechanism of neuronal adaptation in response to changes in the environment or due to brain injury. In this review, we show our results about the effects of synaptic…

The modular and hierarchical organization of the brain is believed to support the coexistence of segregated (specialization) and integrated (binding) information processes. A relevant question is yet to understand how such architecture…

Neurons and Cognition · Quantitative Biology 2025-06-19 Raphaël Bergoin , Alessandro Torcini , Gustavo Deco , Mathias Quoy , Gorka Zamora-López

One of the most striking capabilities behind the learning mechanisms of the brain is the adaptation, through structural and functional plasticity, of its synapses. While synapses have the fundamental role of transmitting information across…

Neural and Evolutionary Computing · Computer Science 2024-06-10 Andrea Ferigo , Elia Cunegatti , Giovanni Iacca

How neuronal circuits achieve credit assignment remains a central unsolved question in systems neuroscience. Various studies have suggested plausible solutions for back-propagating error signals through multi-layer networks. These purely…

Neurons and Cognition · Quantitative Biology 2023-12-12 Julian Rossbroich , Friedemann Zenke

Generalization to out-of-distribution (OOD) circumstances after training remains a challenge for artificial agents. To improve the robustness displayed by plastic Hebbian neural networks, we evolve a set of Hebbian learning rules, where…

Neural and Evolutionary Computing · Computer Science 2021-04-19 Joachim Winther Pedersen , Sebastian Risi

In this paper, we study recurrent neural networks in the presence of pairwise learning rules. We are specifically interested in how the attractor landscapes of such networks become altered as a function of the strength and nature (Hebbian…

Neural and Evolutionary Computing · Computer Science 2023-12-25 Lulu Gong , Xudong Chen , ShiNung Ching

Can lifetime learning expand behavioral diversity over evolutionary time, rather than collapsing it? Prior theory predicts that plasticity reduces variance by buffering organisms against environmental noise. We test this in a competitive…

Artificial Intelligence · Computer Science 2026-04-07 Diego Armando Resendez Prado

The adaptive learning capabilities seen in biological neural networks are largely a product of the self-modifying behavior emerging from online plastic changes in synaptic connectivity. Current methods in Reinforcement Learning (RL) only…

Neural and Evolutionary Computing · Computer Science 2020-06-16 Samuel Schmidgall

Synaptic plasticity is widely accepted to be the mechanism behind learning in the brain's neural networks. A central question is how synapses, with access to only local information about the network, can still organize collectively and…

Neural and Evolutionary Computing · Computer Science 2019-12-06 Dina Obeid , Hugo Ramambason , Cengiz Pehlevan

Much has been learned about plasticity of biological synapses from empirical studies. Hebbian plasticity is driven by correlated activity of presynaptic and postsynaptic neurons. Synapses that converge onto the same neuron often behave as…

Neural and Evolutionary Computing · Computer Science 2017-04-04 H. Sebastian Seung , Jonathan Zung

Deep continual learning requires models to adapt to new tasks without retraining from scratch. However, neural networks can lose their ability to adapt to new tasks after training on previous ones, a phenomenon known as loss of plasticity.…

Machine Learning · Computer Science 2026-05-12 Jiuqi Wang , Jayanth Srinivasa , Claire Chen , Shuze Daniel Liu , Ali Payani , Shangtong Zhang

Deep Convolutional Neural Networks (CNNs) achieve high accuracy but often rely on purely global, gradient-based optimisation, which can lead to overfitting, redundant filters, and reduced interpretability. To address these limitations, we…

Machine Learning · Computer Science 2025-08-28 Davorin Miličević , Ratko Grbić

Memory is a key component of biological neural systems that enables the retention of information over a huge range of temporal scales, ranging from hundreds of milliseconds up to years. While Hebbian plasticity is believed to play a pivotal…

Neural and Evolutionary Computing · Computer Science 2022-05-24 Thomas Limbacher , Ozan Özdenizci , Robert Legenstein

The aim of the present paper is to study the effects of Hebbian learning in random recurrent neural networks with biological connectivity, i.e. sparse connections and separate populations of excitatory and inhibitory neurons. We furthermore…

Neurons and Cognition · Quantitative Biology 2007-06-19 Benoit Siri , Mathias Quoy , Bruno Delord , Bruno Cessac , Hugues Berry