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Large Language Models (LLMs) have propelled groundbreaking advancements across several domains and are commonly used for text generation applications. However, the computational demands of these complex models pose significant challenges,…

The use of Large Language Models (LLMs) in mathematical reasoning has become a cornerstone of related research, demonstrating the intelligence of these models and enabling potential practical applications through their advanced performance,…

Computation and Language · Computer Science 2024-12-20 Kathrin Seßler , Yao Rong , Emek Gözlüklü , Enkelejda Kasneci

Large language models (LLMs) have emerged as powerful tools with transformative potential across numerous domains, including healthcare and medicine. In the medical domain, LLMs hold promise for tasks ranging from clinical decision support…

Computation and Language · Computer Science 2024-05-14 Xiaolan Chen , Jiayang Xiang , Shanfu Lu , Yexin Liu , Mingguang He , Danli Shi

Large language models (LLMs) such as ChatGPT have gained considerable interest across diverse research communities. Their notable ability for text completion and generation has inaugurated a novel paradigm for language-interfaced problem…

Quantitative Methods · Quantitative Biology 2024-02-22 Hengchuang Yin , Zhonghui Gu , Fanhao Wang , Yiparemu Abuduhaibaier , Yanqiao Zhu , Xinming Tu , Xian-Sheng Hua , Xiao Luo , Yizhou Sun

Large Language Models (LLMs) have achieved remarkable success in Natural Language Processing (NLP), yet their cross-lingual performance consistency remains a significant challenge. This paper introduces a novel methodology for efficiently…

Computation and Language · Computer Science 2025-05-27 Zixiang Xu , Yanbo Wang , Yue Huang , Xiuying Chen , Jieyu Zhao , Meng Jiang , Xiangliang Zhang

Large Language Models (LLMs) have seen great advance in both academia and industry, and their popularity results in numerous open-source frameworks and techniques in accelerating LLM pre-training, fine-tuning, and inference. Training and…

Performance · Computer Science 2023-12-04 Longteng Zhang , Xiang Liu , Zeyu Li , Xinglin Pan , Peijie Dong , Ruibo Fan , Rui Guo , Xin Wang , Qiong Luo , Shaohuai Shi , Xiaowen Chu

With the evolution of large language models (LLMs), their robustness against individual simple biases has been enhanced. However, we observe that the ensemble of multiple simple biases still exerts a significant adverse impact on LLMs.…

Computation and Language · Computer Science 2026-04-21 Zhouhao Sun , Zhiyuan Kan , Xiao Ding , Li Du , Bibo Cai , Yang Zhao , Bing Qin , Ting Liu

Large language models (LLMs) have shown remarkable capabilities in general domains, but their application to multi-omics biology remains underexplored. To address this gap, we introduce Biology-Instructions, the first large-scale…

The rapid growth of biomedical literature poses challenges for manual knowledge curation and synthesis. Biomedical Natural Language Processing (BioNLP) automates the process. While Large Language Models (LLMs) have shown promise in general…

Evaluating the abilities of large models and manifesting their gaps are challenging. Current benchmarks adopt either ground-truth-based score-form evaluation on static datasets or indistinct textual chatbot-style human preferences…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Zijian Chen , Lirong Deng , Zhengyu Chen , Kaiwei Zhang , Qi Jia , Yuan Tian , Yucheng Zhu , Guangtao Zhai

Large language models (LLMs) are incredible and versatile tools for text-based tasks that have enabled countless, previously unimaginable, applications. Retrieval models, in contrast, have not yet seen such capable general-purpose models…

Information Retrieval · Computer Science 2025-09-10 Julian Killingback , Hamed Zamani

Large language models are deep learning models with a large number of parameters. The models made noticeable progress on a large number of tasks, and as a consequence allowing them to serve as valuable and versatile tools for a diverse…

Software Engineering · Computer Science 2023-04-11 Maxim Vidgof , Stefan Bachhofner , Jan Mendling

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

The applications of large language models (LLMs) in various biological domains have been explored recently, but their reasoning ability in complex biological systems, such as pathways, remains underexplored, which is crucial for predicting…

Machine Learning · Computer Science 2025-07-23 Haiteng Zhao , Chang Ma , Fangzhi Xu , Lingpeng Kong , Zhi-Hong Deng

Clinical trial matching is a key process in health delivery and discovery. In practice, it is plagued by overwhelming unstructured data and unscalable manual processing. In this paper, we conduct a systematic study on scaling clinical trial…

Small Language Models (SLMs) offer computational efficiency and accessibility, yet a systematic evaluation of their performance and environmental impact remains lacking. We introduce SLM-Bench, the first benchmark specifically designed to…

Computation and Language · Computer Science 2025-09-05 Nghiem Thanh Pham , Tung Kieu , Duc-Manh Nguyen , Son Ha Xuan , Nghia Duong-Trung , Danh Le-Phuoc

Large language model (LLM) agents have demonstrated remarkable potential in advancing scientific discovery. However, their capability in the fundamental yet crucial task of reproducing code from research papers, especially in the NLP…

Large language models (LLMs) have demonstrated broad utility across molecular domains, spanning drug discovery and materials design. Analyzing LLMs' latent representations is crucial for elucidating their underlying mechanisms, improving…

Machine Learning · Computer Science 2026-02-03 Zhuoran Li , Xu Sun , Wanyu Lin , Jiannong Cao

Large language models applied to vast biological datasets have the potential to transform biology by uncovering disease mechanisms and accelerating drug development. However, current models are often siloed, trained separately on…

Scale is often attributed as one of the factors that cause an increase in the performance of LLMs, resulting in models with billion and trillion parameters. One of the limitations of such large models is the high computational requirements…

Machine Learning · Computer Science 2024-05-09 Sher Badshah , Hassan Sajjad
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