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Self-supervised pretraining from static structures of drug-like compounds and proteins enable powerful learned feature representations. Learned features demonstrate state of the art performance on a range of predictive tasks including…

Biomolecules · Quantitative Biology 2025-09-12 Derek Jones , Yue Yang , Felice C. Lightstone , Niema Moshiri , Jonathan E. Allen , Tajana S. Rosing

Uncertainty in optimization is often represented as stochastic parameters in the optimization model. In Predict-Then-Optimize approaches, predictions of a machine learning model are used as values for such parameters, effectively…

Machine Learning · Computer Science 2025-12-03 Pieter Smet

Machine learning-based surrogate models have emerged as more efficient alternatives to numerical solvers for physical simulations over complex geometries, such as car bodies. Many existing models incorporate the simulation mesh as an…

Machine Learning · Computer Science 2026-01-27 Jan Hagnberger , Mathias Niepert

This paper considers the creation of parametric surrogate models for applications in science and engineering where the goal is to predict high-dimensional spatiotemporal output quantities of interest, such as pressure, temperature and…

Computational Physics · Physics 2022-03-24 Chi Hoang , Kenny Chowdhary , Kookjin Lee , Jaideep Ray

Agent technology is a software paradigm that permits to implement large and complex distributed applications. In order to assist the development of multi-agent systems, agent-oriented methodologies (AOM) have been created in the last years…

Software Engineering · Computer Science 2014-03-13 Mohamed Garoui , Belhassen Mazigh , Béchir El Ayeb , Abderrafiaa Koukam

Probabilistic model checking is a technique for formal automated reasoning about software or hardware systems that operate in the context of uncertainty or stochasticity. It builds upon ideas and techniques from a diverse range of fields,…

Logic in Computer Science · Computer Science 2023-08-08 David Parker

We propose a new approach for building recommender systems by adapting surrogate-assisted interactive genetic algorithms. A pool of user-evaluated items is used to construct an approximative model which serves as a surrogate fitness…

Neural and Evolutionary Computing · Computer Science 2019-08-09 Thomas Gabor , Philipp Altmann

The key challenge in multiagent learning is learning a best response to the behaviour of other agents, which may be non-stationary: if the other agents adapt their strategy as well, the learning target moves. Disparate streams of research…

Multiagent Systems · Computer Science 2019-03-13 Pablo Hernandez-Leal , Michael Kaisers , Tim Baarslag , Enrique Munoz de Cote

This study introduces a surrogate modeling framework merging proper orthogonal decomposition, long short-term memory networks, and multi-task learning, to accurately predict elastoplastic deformations in real-time. Superior to single-task…

Computational Engineering, Finance, and Science · Computer Science 2024-11-11 Ruben Schmeitz , Joris Remmers , Olga Mula , Olaf van der Sluis

Simulation models are valuable tools for resource usage estimation and capacity planning. In many situations, reliable data is not available. We introduce the BuB simulator, which requires only the specification of plausible intervals for…

Applications · Statistics 2020-09-08 Thomas Bartz-Beielstein , Eva Bartz , Frederik Rehbach , Olaf Mersmann

The computational resources required to solve the full 3D inversion of time-domain electromagnetic data are immense. To overcome the time-consuming 3D simulations, we construct a surrogate model, more precisely, a data-driven statistical…

Geophysics · Physics 2024-07-10 Wouter Deleersnyder , David Dudal , Thomas Hermans

When evaluating quantities of interest that depend on the solutions to differential equations, we inevitably face the trade-off between accuracy and efficiency. Especially for parametrized, time dependent problems in engineering…

Numerical Analysis · Mathematics 2022-12-21 Paolo Conti , Mengwu Guo , Andrea Manzoni , Jan S. Hesthaven

Recently, a surrogate model was proposed that employs a factorization machine to approximate the underlying input-output mapping of the original system, with quantum annealing used to optimize the resulting surrogate function. Inspired by…

Machine Learning · Computer Science 2026-01-21 Anbang Wang , Dunbo Cai , Yu Zhang , Yangqing Huang , Xiangyang Feng , Zhihong Zhang

Simulations of crystal growth are performed by using Convolutional Recurrent Neural Network surrogate models, trained on a dataset of time sequences computed by numerical integration of Allen-Cahn dynamics including faceting via kinetic…

Materials Science · Physics 2026-04-24 Matteo Rigoni , Daniele Lanzoni , Francesco Montalenti , Roberto Bergamaschini

A surrogate model that accurately predicts distribution system voltages is crucial for reliable smart grid planning and operation. This letter proposes a fixed-point data-driven surrogate modeling method that employs a limited dataset to…

Systems and Control · Electrical Eng. & Systems 2024-01-01 Hoang Tien Nguyen , Young-Jin Kim , Dae-Hyun Choi

Modeling coordination among generative agents in complex multi-round decision-making presents a core challenge for AI and operations management. Although behavioral experiments have revealed cognitive biases behind supply chain…

Multiagent Systems · Computer Science 2026-04-21 Jiuyun Jiang , Yuecheng Hong , Bo Yang , Jin Yang , Guangxin Jiang , Xiaomeng Guo , Guang Xiao

Learning accurate, data-driven predictive models for multiple interacting agents following unknown dynamics is crucial in many real-world physical and social systems. In many scenarios, dynamics prediction must be performed under incomplete…

Multiagent Systems · Computer Science 2024-04-03 Hemant Kumawat , Biswadeep Chakraborty , Saibal Mukhopadhyay

Agent-based models (ABMs) are increasingly used to study complex economic phenomena such as endogenous growth, but their analysis typically relies on ad-hoc Monte Carlo exercises without formal statistical guarantees. We show how…

Multiagent Systems · Computer Science 2026-04-07 Stefano Blando , Giorgio Fagiolo , Daniele Giachini , Andrea Vandin , Ernest Ivanaj

This paper presents a novel dynamic model for slug flow crystallizers that addresses the challenges of spatial distribution without backmixing or diffusion, potentially enabling advanced model-based control. The developed model can…

Systems and Control · Electrical Eng. & Systems 2025-10-21 Collin R. Johnson , Stijn de Vries , Kerstin Wohlgemuth , Sergio Lucia

Multitask learning is widely used in practice to train a low-resource target task by augmenting it with multiple related source tasks. Yet, naively combining all the source tasks with a target task does not always improve the prediction…

Machine Learning · Computer Science 2023-12-29 Dongyue Li , Huy L. Nguyen , Hongyang R. Zhang
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