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Multimodal Large Language Models (MLLMs) hold promise for accelerating scientific discovery by interpreting complex experimental procedures. However, their true capabilities are poorly understood, as existing benchmarks neglect the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Yicheng Xu , Yue Wu , Jiashuo Yu , Ziang Yan , Tianxiang Jiang , Yinan He , Qingsong Zhao , Kai Chen , Yu Qiao , Limin Wang , Manabu Okumura , Yi Wang

Multilingual Large Language Models (MLLMs) represent a pivotal advancement in democratizing artificial intelligence across linguistic boundaries. While theoretical foundations are well-established, practical implementation guidelines remain…

Computation and Language · Computer Science 2024-10-24 Junhua Liu , Bin Fu

Large language models (LLMs) have a transformative impact on a variety of scientific tasks across disciplines including biology, chemistry, medicine, and physics. However, ensuring the safety alignment of these models in scientific research…

The rapid advancement of large language models (LLMs) and multimodal foundation models has sparked growing interest in their potential for scientific research. However, scientific intelligence encompasses a broad spectrum of abilities…

Artificial Intelligence · Computer Science 2025-12-30 Yaping Zhang , Qixuan Zhang , Xingquan Zhang , Zhiyuan Chen , Wenwen Zhuang , Yupu Liang , Lu Xiang , Yang Zhao , Jiajun Zhang , Yu Zhou , Chengqing Zong

Large language models (LLMs) have demonstrated their remarkable performance across various language understanding tasks. While emerging benchmarks have been proposed to evaluate LLMs in various domains such as mathematics and computer…

Artificial Intelligence · Computer Science 2024-10-28 Junnan Dong , Zijin Hong , Yuanchen Bei , Feiran Huang , Xinrun Wang , Xiao Huang

The ability to process information from multiple modalities and to reason through it step-by-step remains a critical challenge in advancing artificial intelligence. However, existing reasoning benchmarks focus on text-only reasoning, or…

Artificial Intelligence · Computer Science 2025-07-01 Yulun Jiang , Yekun Chai , Maria Brbić , Michael Moor

Background: The rapid integration of foundation models into clinical practice and public health necessitates a rigorous evaluation of their true clinical reasoning capabilities beyond narrow examination success. Current benchmarks,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Dingyu Wang , Zimu Yuan , Jiajun Liu , Shanggui Liu , Nan Zhou , Tianxing Xu , Di Huang , Dong Jiang

Active learning (AL) accelerates scientific discovery by prioritizing the most informative experiments, but traditional machine learning (ML) models used in AL suffer from cold-start limitations and domain-specific feature engineering,…

Machine Learning · Computer Science 2025-12-05 Hongchen Wang , Rafael Espinosa Castañeda , Jay R. Werber , Yao Fehlis , Edward Kim , Jason Hattrick-Simpers

Large language models (LLMs) showcase increasingly impressive English benchmark scores, however their performance profiles remain inconsistent across multilingual settings. To address this gap, we introduce PolyPrompt, a novel,…

Computation and Language · Computer Science 2025-06-04 Nathan Roll

Understanding the world and explaining it with scientific theories is a central aspiration of artificial intelligence research. Proposing theories, designing experiments to test them, and then revising them based on data are fundamental to…

Machine Learning · Computer Science 2025-10-16 Kanishk Gandhi , Michael Y. Li , Lyle Goodyear , Agam Bhatia , Louise Li , Aditi Bhaskar , Mohammed Zaman , Noah D. Goodman

K-12 science classrooms are rich sites of inquiry where students coordinate phenomena, evidence, and explanatory models through discourse; yet, the multimodal complexity of these interactions has made automated analysis elusive. Existing…

Computers and Society · Computer Science 2026-03-18 Yixuan Shen , Peng He , Honglu Liu , Jinxuan Fan , Yuyang Ji , Tingting Li , Tianlong Chen , Kaidi Xu , Feng Liu

Designing experiments and result interpretations are core scientific competencies, particularly in biology, where researchers perturb complex systems to uncover the underlying systems. Recent efforts to evaluate the scientific capabilities…

Large Language Models (LLMs) have demonstrated remarkable capabilities on general text; however, their proficiency in specialized scientific domains that require deep, interconnected knowledge remains largely uncharacterized. Metabolomics…

Computation and Language · Computer Science 2025-10-17 Yuxing Lu , Xukai Zhao , J. Ben Tamo , Micky C. Nnamdi , Rui Peng , Shuang Zeng , Xingyu Hu , Jinzhuo Wang , May D. Wang

Multimodal Large Language Models (MLLMs) excel at recognizing individual visual elements and reasoning over simple linear diagrams. However, when faced with complex topological structures involving branching paths, converging flows, and…

Artificial Intelligence · Computer Science 2026-04-24 Qiang Xu , Shengyuan Bai , Yu Wang , He Cao , Leqing Chen , Yuanyuan Liu , Bin Feng , Zijing Liu , Yu Li

Recent claims of strong performance by Large Language Models (LLMs) on causal discovery are undermined by a key flaw: many evaluations rely on benchmarks likely included in pretraining corpora. Thus, apparent success suggests that LLM-only…

Logical reasoning is a fundamental aspect of human intelligence and an essential capability for multimodal large language models (MLLMs). Despite the significant advancement in multimodal reasoning, existing benchmarks fail to…

Artificial Intelligence · Computer Science 2025-05-28 Jiakang Yuan , Tianshuo Peng , Yilei Jiang , Yiting Lu , Renrui Zhang , Kaituo Feng , Chaoyou Fu , Tao Chen , Lei Bai , Bo Zhang , Xiangyu Yue

Large language models (LLMs) hold considerable potential for advancing scientific discovery, yet systematic assessment of their dynamic reasoning in real-world research remains limited. Current scientific evaluation benchmarks predominantly…

Computation and Language · Computer Science 2026-03-27 Taolin Han , Shuang Wu , Jinghang Wang , Yuhao Zhou , Renquan Lv , Bing Zhao , Wei Hu

Leveraging Multi-modal Large Language Models (MLLMs) to accelerate frontier scientific research is promising, yet how to rigorously evaluate such systems remains unclear. Existing benchmarks mainly focus on single-document understanding,…

Artificial Intelligence · Computer Science 2026-04-14 Lei Xiong , Huaying Yuan , Zheng Liu , Zhao Cao , Zhicheng Dou

Recent progress in Multimodal Large Language Models (MLLMs) has demonstrated remarkable advances in perception and reasoning, suggesting their potential for embodied intelligence. While recent studies have evaluated embodied MLLMs in…

Artificial Intelligence · Computer Science 2026-04-23 Shengyu Guo , Tongrui Ye , Jianbo Zhang , Zicheng Zhang , Chunyi Li , Guangtao Zhai

Recent advancements in artificial intelligence have sparked interest in scientific assistants that could support researchers across the full spectrum of scientific workflows, from literature review to experimental design and data analysis.…

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