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Background: Inverse probability of treatment weighting (IPTW) is used for confounding adjustment in observational studies. Newer weighting methods include energy balancing (EB), kernel optimal matching (KOM), and tailored-loss covariate…

Methodology · Statistics 2026-01-15 Etienne Peyrot , Raphaël Porcher , Francois Petit

In randomized clinical trials, adjusting for baseline covariates can improve credibility and efficiency for demonstrating and quantifying treatment effects. This article studies the augmented inverse propensity weighted (AIPW) estimator,…

Methodology · Statistics 2024-03-27 Marlena S. Bannick , Jun Shao , Jingyi Liu , Yu Du , Yanyao Yi , Ting Ye

Clinical trials are the gold standard for assessing the effectiveness and safety of drugs for treating diseases. Given the vast design space of drug molecules, elevated financial cost, and multi-year timeline of these trials, research on…

Machine Learning · Computer Science 2025-01-14 Yiqing Zhang , Xiaozhong Liu , Fabricio Murai

Conventional treatment policies map patient covariates to a single recommended intervention in order to maximize expected clinical outcomes. Although a rich body of causal inference methods has been developed to estimate such policies,…

Machine Learning · Computer Science 2026-05-20 Laura Fuentes-Vicente , Mathieu Even , Gaëlle Dormion , Antoine Chambaz , Uri Shalit , Julie Josse

Predictive uncertainty-a model's self awareness regarding its accuracy on an input-is key for both building robust models via training interventions and for test-time applications such as selective classification. We propose a novel…

Machine Learning · Computer Science 2024-01-04 Nishant Jain , Karthikeyan Shanmugam , Pradeep Shenoy

Matching on covariates is a well-established framework for estimating causal effects in observational studies. The principal challenge stems from the often high-dimensional structure of the problem. Many methods have been introduced to…

Methodology · Statistics 2022-07-12 Florian Gunsilius , Yuliang Xu

Learning from set-structured data is a fundamental problem that has recently attracted increasing attention, where a series of summary networks are introduced to deal with the set input. In fact, many meta-learning problems can be treated…

Machine Learning · Computer Science 2023-03-08 Dandan Guo , Long Tian , Minghe Zhang , Mingyuan Zhou , Hongyuan Zha

Statistical decision algorithms are increasingly deployed in domains where ground-truth labels are hard to obtain, such as hiring, university admissions, and content moderation. In these settings, models are typically trained on historical…

Machine Learning · Computer Science 2026-05-21 Calvin Isley , Johann D. Gaebler , Sharad Goel

Generating probabilistic forecasts of potential outcomes and individual treatment effects (ITE) is essential for risk-aware decision-making in domains such as healthcare, policy, marketing, and finance. We propose two novel methods: the…

Machine Learning · Computer Science 2025-09-24 Jef Jonkers , Jarne Verhaeghe , Glenn Van Wallendael , Luc Duchateau , Sofie Van Hoecke

Conventional semi-supervised contrastive learning methods assign pseudo-labels only to samples whose highest predicted class probability exceeds a predefined threshold, and then perform supervised contrastive learning using those selected…

Machine Learning · Computer Science 2026-01-09 Shogo Nakayama , Masahiro Okuda

Transfer of pre-trained representations can improve sample efficiency and reduce computational requirements for new tasks. However, representations used for transfer are usually generic, and are not tailored to a particular distribution of…

Learning a transport model that maps a source distribution to a target distribution is a canonical problem in machine learning, but scientific applications increasingly require models that can generalize to source and target distributions…

Machine Learning · Computer Science 2026-03-06 Nic Fishman , Gokul Gowri , Paolo L. B. Fischer , Marinka Zitnik , Omar Abudayyeh , Jonathan Gootenberg

The purpose of this work is to transport the information from multiple randomized controlled trials to the target population where we only have the control group data. Previous works rely critically on the mean exchangeability assumption.…

Machine Learning · Statistics 2023-09-29 Yuhang Zhang , Yue Liu , Zhihua Zhang

In conventional randomized controlled trials, adjustment for baseline values of covariates known to be at least moderately associated with the outcome increases the power of the trial. Recent work has shown particular benefit for more…

Methodology · Statistics 2023-11-27 James Willard , Shirin Golchi , Erica EM Moodie

Conformal Prediction (CP) is a principled framework for quantifying uncertainty in blackbox learning models, by constructing prediction sets with finite-sample coverage guarantees. Traditional approaches rely on scalar nonconformity scores,…

Machine Learning · Statistics 2025-05-07 Gauthier Thurin , Kimia Nadjahi , Claire Boyer

Transfer learning has achieved promising results by leveraging knowledge from the source domain to annotate the target domain which has few or none labels. Existing methods often seek to minimize the distribution divergence between domains,…

Machine Learning · Computer Science 2018-07-03 Jindong Wang , Yiqiang Chen , Shuji Hao , Wenjie Feng , Zhiqi Shen

In randomized clinical trials, adjustments for baseline covariates at both design and analysis stages are highly encouraged by regulatory agencies. A recent trend is to use a model-assisted approach for covariate adjustment to gain…

Methodology · Statistics 2021-07-14 Ting Ye , Jun Shao , Yanyao Yi , Qingyuan Zhao

Transfer-learning methods aim to improve performance in a data-scarce target domain using a model pretrained on a data-rich source domain. A cost-efficient strategy, linear probing, involves freezing the source model and training a new…

Machine Learning · Computer Science 2022-07-27 Utku Evci , Vincent Dumoulin , Hugo Larochelle , Michael C. Mozer

In this paper we propose an improved method for transfer learning that takes into account the balance between target and source data. This method builds on the state-of-the-art Multisource Tradaboost, but weighs the importance of each…

Machine Learning · Computer Science 2019-03-28 João Antunes , Alexandre Bernardino , Asim Smailagic , Daniel Siewiorek

We study a fundamental transfer learning process from source to target linear regression tasks, including overparameterized settings where there are more learned parameters than data samples. The target task learning is addressed by using…

Machine Learning · Computer Science 2024-06-03 Yehuda Dar , Daniel LeJeune , Richard G. Baraniuk
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