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Achieving domain generalization in medical imaging poses a significant challenge, primarily due to the limited availability of publicly labeled datasets in this domain. This limitation arises from concerns related to data privacy and the…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Ahmed Radwan , Islam Osman , Mohamed S. Shehata

Most statistical learning algorithms rely on an over-simplified assumption, that is, the train and test data are independent and identically distributed. In real-world scenarios, however, it is common for models to encounter data from new…

Image and Video Processing · Electrical Eng. & Systems 2023-04-07 Zheyuan Zhang , Bin Wang , Lanhong Yao , Ugur Demir , Debesh Jha , Ismail Baris Turkbey , Boqing Gong , Ulas Bagci

Domain shift presents a significant challenge in applying Deep Learning to the segmentation of 3D medical images from sources like Magnetic Resonance Imaging (MRI) and Computed Tomography (CT). Although numerous Domain Adaptation methods…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Boris Shirokikh , Anvar Kurmukov , Mariia Donskova , Valentin Samokhin , Mikhail Belyaev , Ivan Oseledets

Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yurong Chen

Medical image artificial intelligence models often achieve strong performance in single-center or single-device settings, yet their effectiveness frequently deteriorates in real-world cross-center deployment due to domain shift, limiting…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jingsong Xia , Siqi Wang

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Anwai Archit , Constantin Pape

Recent advances in deep learning methods have come to define the state-of-the-art for many medical imaging applications, surpassing even human judgment in several tasks. Those models, however, when trained to reduce the empirical risk on a…

Computer Vision and Pattern Recognition · Computer Science 2019-01-14 Christian S. Perone , Pedro Ballester , Rodrigo C. Barros , Julien Cohen-Adad

Domain generalisation in computational histopathology is challenging because the images are substantially affected by differences among hospitals due to factors like fixation and staining of tissue and imaging equipment. We hypothesise that…

Image and Video Processing · Electrical Eng. & Systems 2024-11-15 Dhananjay Tomar , Alexander Binder , Andreas Kleppe

Medical images are usually collected from multiple domains, leading to domain shifts that impair the performance of medical image segmentation models. Domain Generalization (DG) aims to address this issue by training a robust model with…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Xi Chen , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane

Deep learning models often encounter challenges in making accurate inferences when there are domain shifts between the source and target data. This issue is particularly pronounced in clinical settings due to the scarcity of annotated data…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Heng Li , Haojin Li , Jianyu Chen , Mingyang Ou , Hai Shu , Heng Miao

Model generalization capacity at domain shift (e.g., various imaging protocols and scanners) is crucial for deep learning methods in real-world clinical deployment. This paper tackles the challenging problem of domain generalization, i.e.,…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Quande Liu , Qi Dou , Pheng-Ann Heng

Modern deep neural networks struggle to transfer knowledge and generalize across diverse domains when deployed to real-world applications. Currently, domain generalization (DG) is introduced to learn a universal representation from multiple…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Yijun Yang , Shujun Wang , Lei Zhu , Lequan Yu

This work provides a strong baseline for the problem of multi-source multi-target domain adaptation and generalization in medical imaging. Using a diverse collection of ten chest X-ray datasets, we empirically demonstrate the benefits of…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Li Yao , Jordan Prosky , Ben Covington , Kevin Lyman

Deep networks are now ubiquitous in large-scale multi-center imaging studies. However, the direct aggregation of images across sites is contraindicated for downstream statistical and deep learning-based image analysis due to inconsistent…

Image and Video Processing · Electrical Eng. & Systems 2021-04-16 Mengwei Ren , Neel Dey , James Fishbaugh , Guido Gerig

Foundation models have transformed vision and language by learning general-purpose representations from large-scale unlabeled data, yet 3D medical imaging lacks analogous approaches. Existing self-supervised methods rely on low-level…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Yunhe Gao , Yabin Zhang , Chong Wang , Jiaming Liu , Maya Varma , Jean-Benoit Delbrouck , Akshay Chaudhari , Curtis Langlotz

This study introduces a novel framework for enhancing domain generalization in medical imaging, specifically focusing on utilizing unlabelled multi-view colour fundus photographs. Unlike traditional approaches that rely on single-view…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Ze Chen , Gongyu Zhang , Jiayu Huo , Joan Nunez do Rio , Charalampos Komninos , Yang Liu , Rachel Sparks , Sebastien Ourselin , Christos Bergeles , Timothy Jackson

The problem of domain generalization is to learn from multiple training domains, and extract a domain-agnostic model that can then be applied to an unseen domain. Domain generalization (DG) has a clear motivation in contexts where there are…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 Da Li , Yongxin Yang , Yi-Zhe Song , Timothy M. Hospedales

Current machine learning methods for medical image analysis primarily focus on developing models tailored for their specific tasks, utilizing data within their target domain. These specialized models tend to be data-hungry and often exhibit…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Ece Ozkan , Xavier Boix

Purpose: The segmentation of brain tumors is one of the most active areas of medical image analysis. While current methods perform superhuman on benchmark data sets, their applicability in daily clinical practice has not been evaluated. In…

Image and Video Processing · Electrical Eng. & Systems 2020-12-17 Sabine Müller , Joachim Weickert , Norbert Graf

Semantic segmentation of medical images is pivotal in applications like disease diagnosis and treatment planning. While deep learning has excelled in automating this task, a major hurdle is the need for numerous annotated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-09-02 Li Zhang , Basu Jindal , Ahmed Alaa , Robert Weinreb , David Wilson , Eran Segal , James Zou , Pengtao Xie