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This paper contributes to interpretable machine learning via visual knowledge discovery in general line coordinates (GLC). The concepts of hyperblocks as interpretable dataset units and general line coordinates are combined to create a…

Machine Learning · Computer Science 2022-05-10 Charles Recaido , Boris Kovalerchuk

Clinical diagnosis is a highly specialized discipline requiring both domain expertise and strict adherence to rigorous guidelines. While current AI-driven medical research predominantly focuses on knowledge graphs or natural text…

Machine Learning · Computer Science 2025-12-12 Haolin Li , Tianjie Dai , Zhe Chen , Siyuan Du , Jiangchao Yao , Ya Zhang , Yanfeng Wang

Problem lists are intended to provide clinicians with a relevant summary of patient medical issues and are embedded in many electronic health record systems. Despite their importance, problem lists are often cluttered with resolved or…

Information Retrieval · Computer Science 2020-08-05 Justin Lovelace , Nathan C. Hurley , Adrian D. Haimovich , Bobak J. Mortazavi

Compliance at web scale poses practical challenges: each request may require a regulatory assessment. Regulatory texts (e.g., the General Data Protection Regulation, GDPR) are cross-referential and normative, while runtime contexts are…

Artificial Intelligence · Computer Science 2025-10-31 Jiseong Chung , Ronny Ko , Wonchul Yoo , Makoto Onizuka , Sungmok Kim , Tae-Wan Kim , Won-Yong Shin

Knowledge Graphs have been one of the fundamental methods for integrating heterogeneous data sources. Integrating heterogeneous data sources is crucial, especially in the biomedical domain, where central data-driven tasks such as drug…

Machine Learning · Computer Science 2020-12-22 Islam Akef Ebeid , Majdi Hassan , Tingyi Wanyan , Jack Roper , Abhik Seal , Ying Ding

Graph recommendation methods, representing a connected interaction perspective, reformulate user-item interactions as graphs to leverage graph structure and topology to recommend and have proved practical effectiveness at scale. Large…

Artificial Intelligence · Computer Science 2025-07-18 Xinyuan Wang , Liang Wu , Liangjie Hong , Hao Liu , Yanjie Fu

The reliable evaluation of large language models (LLMs) in medical applications remains an open challenge, particularly in capturing the complexity of multi-turn doctor-patient interactions that unfold in real clinical environments.…

Artificial Intelligence · Computer Science 2025-10-15 Yuechun Yu , Han Ying , Haoan Jin , Wenjian Jiang , Dong Xian , Binghao Wang , Zhou Yang , Mengyue Wu

The work in this paper evaluates zero-shot and few-shot large language models (LLMs) for safety-critical clinical action extraction using the CLIP discharge-note dataset, with particular emphasis on transitions of care and post-discharge…

Artificial Intelligence · Computer Science 2026-05-08 Shivali Dalmia , Ananya Mantravadi , Prasanna Desikan

Large language models (LLMs) are widely used, but they often generate subtle factual errors, especially in long-form text. These errors are fatal in some specialized domains such as medicine. Existing fact-checking with grounding documents…

Computation and Language · Computer Science 2025-05-29 Yingjian Chen , Haoran Liu , Yinhong Liu , Jinxiang Xie , Rui Yang , Han Yuan , Yanran Fu , Peng Yuan Zhou , Qingyu Chen , James Caverlee , Irene Li

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Liver cirrhosis is a major global health problem causing millions of deaths annually, and timely detection with aggressive treatment can significantly improve patients' quality of life. Modelling complex diseases from biomedical data is…

Other Quantitative Biology · Quantitative Biology 2026-04-29 Xueyuan Huang , Yuheng Wang , Yuanzhi He , Siqi Gou , Lu Bai , Wenqian Wu , Peifeng Liu , Aijia Wang , Tianhui Fan , Ze Zhou , Jiayu Xu

Pathological diagnosis is vital for determining disease characteristics, guiding treatment, and assessing prognosis, relying heavily on detailed, multi-scale analysis of high-resolution whole slide images (WSI). However, existing large…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Shengxuming Zhang , Weihan Li , Tianhong Gao , Jiacong Hu , Haoming Luo , Xiuming Zhang , Jing Zhang , Mingli Song , Zunlei Feng

In this paper, we propose a reservoir computing-based and directed graph analysis pipeline. The goal of this pipeline is to define an efficient brain representation for connectivity in stroke data derived from magnetic resonance imaging.…

Machine Learning · Computer Science 2025-01-28 Wojciech Ciezobka , Joan Falco-Roget , Cemal Koba , Alessandro Crimi

Medical diagnosis is not a single prediction from a fully specified vignette. It is a sequential workup: clinicians decide what evidence to obtain, revise a differential diagnosis, and stop when the diagnosis is sufficiently supported. Most…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Jiazhen Pan , Weixiang Shen , Jun Li , Julian Canisius , Felix Bitzer , Paula Roßmüller , Jiancheng Yang , Virginie Kreutzinger , Daniel Rueckert , Benedikt Wiestler

Recent advances in vision language models (VLMs) have enabled broad progress in the general medical field. However, pathology still remains a more challenging subdomain, with current pathology specific VLMs exhibiting limitations in both…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Wenchuan Zhang , Penghao Zhang , Jingru Guo , Tao Cheng , Jie Chen , Shuwan Zhang , Zhang Zhang , Yuhao Yi , Hong Bu

Modern information systems require autonomous agents capable of navigating complex workflows, yet current methodologies often struggle with the transition from structured metadata parsing to general environmental perception. While the…

Artificial Intelligence · Computer Science 2026-05-28 Susanna Cifani , Mario Luca Bernardi , Marta Cimitile

Background: Recruitment for cohorts involving complex liver diseases, such as hepatocellular carcinoma and liver cirrhosis, often requires interpreting semantically complex criteria. Traditional manual screening methods are time-consuming…

Artificial Intelligence · Computer Science 2025-02-27 Xiongbin Gui , Hanlin Lv , Xiao Wang , Longting Lv , Yi Xiao , Lei Wang

Manual chart review remains an extremely time-consuming and resource-intensive component of clinical research, requiring experts to extract often complex information from unstructured electronic health record (EHR) narratives. We present a…

Large language models (LLMs) have demonstrated strong performance and rapid progress in a wide range of medical reasoning tasks. However, their sequential autoregressive decoding forces inherently parallel clinical reasoning, such as…

Machine Learning · Computer Science 2026-04-17 Jianwen Chen , Xinyu Yang , Peng Xia , Arian Azarang , Yueh Z Lee , Gang Li , Hongtu Zhu , Yun Li , Beidi Chen , Huaxiu Yao

Although rapid advancements in Large Language Models (LLMs) are facilitating the integration of artificial intelligence-based applications and services in healthcare, limited research has focused on the systematic evaluation of medical…

Artificial Intelligence · Computer Science 2024-11-12 MD Ragib Shahriyear