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Single-cell RNA sequencing (scRNA-seq) data simulation is limited by classical methods that rely on linear correlations, failing to capture the intrinsic, nonlinear dependencies. No existing simulator jointly models gene-gene and cell-cell…

Quantitative Methods · Quantitative Biology 2025-12-22 Selim Romero , Vignesh S. Kumar , Robert S. Chapkin , James J. Cai

Single-cell RNA sequencing (scRNA-seq) has revealed complex cellular heterogeneity, but recent studies emphasize that understanding biological function also requires modeling cell-cell communication (CCC), the signaling interactions…

Machine Learning · Computer Science 2025-12-29 Cong Qi , Yeqing Chen , Zhi Wei

In multicellular organisms, cells coordinate their activities through cell-cell communication (CCC), which is crucial for development, tissue homeostasis, and disease progression. Recent advances in single-cell and spatial omics…

Quantitative Methods · Quantitative Biology 2026-03-24 Xiangzheng Cheng , Haili Huang , Ye Su , Qing Nie , Xiufen Zou , Suoqin Jin

In this work, we present a quantum circuit model for inferring gene regulatory networks (GRNs). The model is based on the idea of using qubit-qubit entanglement to simulate interactions between genes. We provide preliminary results that…

Emerging Technologies · Computer Science 2022-07-06 Cristhian Roman-Vicharra , James J. Cai

Quantum-like modeling (QLM) - quantum theory applications outside of physics - are intensively developed with applications in biology, cognition, psychology, and decision-making. For cognition, QLM should be distinguished from quantum…

Neurons and Cognition · Quantitative Biology 2025-12-16 Andrei Khrennikov , Makiko Yamada

A promising platform for semi-device-independent quantum information is prepare-and-measure experiments restricted only by a bound on the energy of the communication. Here, we investigate the role of shared entanglement in such scenarios.…

Quantum Physics · Physics 2026-03-19 Carles Roch I Carceller , Armin Tavakoli

High-fidelity circuit execution on noisy intermediate-scale quantum devices is bottlenecked by compilation pipelines that disregard complex, correlated noise. To address this, this methodology article proposes a quantum machine learning…

Topological quantum field theories (TQFT) encode properties of quantum states in the topological features of abstract manifolds. One can use the topological avatars of quantum states to develop intuition about different concepts and…

High Energy Physics - Theory · Physics 2023-07-26 Dmitry Melnikov

Distributed quantum information processing is a promising platform for scaling up quantum information processing, where small- and intermediate-scale quantum devices are connected by a network of quantum channels for communicating quantum…

Quantum Physics · Physics 2019-03-26 Hayata Yamasaki

The paradigm of variational quantum classifiers (VQCs) encodes \textit{classical information} as quantum states, followed by quantum processing and then measurements to generate classical predictions. VQCs are promising candidates for…

Quantum Physics · Physics 2023-08-01 Hideyuki Miyahara , Vwani Roychowdhury

Entanglement is a fundamental feature of quantum mechanics, playing a crucial role in quantum information processing. However, classifying entangled states, particularly in the mixed-state regime, remains a challenging problem, especially…

Offline reinforcement learning enables policy learning from pre-collected datasets without environment interaction, but existing Decision Transformer (DT) architectures struggle with long-horizon credit assignment and complex state-action…

Machine Learning · Computer Science 2025-12-18 Abraham Itzhak Weinberg

The ability to realize high-fidelity quantum communication is one of the many facets required to build generic quantum computing devices. In addition to quantum processing, sensing, and storage, transferring the resulting quantum states…

The rapid development of quantum computing has demonstrated many unique characteristics of quantum advantages, such as richer feature representation and more secured protection on model parameters. This work proposes a vertical federated…

Computation and Language · Computer Science 2022-03-08 Chao-Han Huck Yang , Jun Qi , Samuel Yen-Chi Chen , Yu Tsao , Pin-Yu Chen

Modeling cellular states and predicting their responses to perturbations are central challenges in computational biology and the development of virtual cells. Existing foundation models for single-cell transcriptomics provide powerful…

Quantitative Methods · Quantitative Biology 2026-03-31 Han Zhang , Guo-Hua Yuan , Chaohao Yuan , Tingyang Xu , Tian Bian , Hong Cheng , Wenbing Huang , Deli Zhao , Yu Rong

We show that the inherent entanglement of the ground state of strongly correlated systems can be exploited for both classical and quantum communications. Our strategy is based on a single qubit rotation which encodes information in the…

Quantum Physics · Physics 2011-08-08 Song Yang , Abolfazl Bayat , Sougato Bose

Quantum communication is based on the generation of quantum states and exploitation of quantum resources for communication protocols. Currently, photons are considered as the optimal carrier of information, because they enable long-distance…

Quantum Physics · Physics 2023-07-13 Liat Nemirovsky-Levy , Uzi Pereg , Mordechai Segev

The role of entanglement and quantum correlations in complex physical systems and quantum information processing devices has become a topic of intense study in the past two decades. In this work we present new tools for learning about…

Quantum Physics · Physics 2017-03-01 Michel Boyer , Aharon Brodutch , Tal Mor

Entanglement has evolved from an enigmatic concept of quantum physics to a key ingredient of quantum technology. It explains correlations between measurement outcomes that contradict classical physics, and has been widely explored with…

Quantum Physics · Physics 2024-06-05 Philip Thomas , Leonardo Ruscio , Olivier Morin , Gerhard Rempe

Quantum dynamics of coherent states is studied within quantum field theory using two complementary methods: by organizing the evolution as a Taylor series in elapsed time and by perturbative expansion in coupling within the…

High Energy Physics - Theory · Physics 2021-10-13 Lasha Berezhiani , Michael Zantedeschi
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