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AI-assisted radiological interpretation is based on predominantly narrow, single-task models. This approach is impractical for covering the vast spectrum of imaging modalities, diseases, and radiological findings. Foundation models (FMs)…

Foundation models (FMs) have shown transformative potential in radiology by performing diverse, complex tasks across imaging modalities. Here, we developed CT-FM, a large-scale 3D image-based pre-trained model designed explicitly for…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Suraj Pai , Ibrahim Hadzic , Dennis Bontempi , Keno Bressem , Benjamin H. Kann , Andriy Fedorov , Raymond H. Mak , Hugo J. W. L. Aerts

While the pretraining of Foundation Models (FMs) for remote sensing (RS) imagery is on the rise, models remain restricted to a few hundred million parameters. Scaling models to billions of parameters has been shown to yield unprecedented…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Philipe Dias , Aristeidis Tsaris , Jordan Bowman , Abhishek Potnis , Jacob Arndt , H. Lexie Yang , Dalton Lunga

Recent advances in artificial intelligence have witnessed the emergence of large-scale deep learning models capable of interpreting and generating both textual and imaging data. Such models, typically referred to as foundation models, are…

Foundation models (FMs) have emerged as a transformative paradigm in medical image analysis, offering the potential to provide generalizable, task-agnostic solutions across a wide range of clinical tasks and imaging modalities. Their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

The field of computational pathology has recently seen rapid advances driven by the development of modern vision foundation models (FMs), typically trained on vast collections of pathology images. Recent studies demonstrate that increasing…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Mikhail Karasikov , Joost van Doorn , Nicolas Känzig , Melis Erdal Cesur , Hugo Mark Horlings , Robert Berke , Fei Tang , Sebastian Otálora

Foundation models (FMs) are changing the way medical images are analyzed by learning from large collections of unlabeled data. Instead of relying on manually annotated examples, FMs are pre-trained to learn general-purpose visual features…

Driven by the recent advances in deep learning methods and, in particular, by the development of modern self-supervised learning algorithms, increased interest and efforts have been devoted to build foundation models (FMs) for medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 kaiko. ai , Nanne Aben , Edwin D. de Jong , Ioannis Gatopoulos , Nicolas Känzig , Mikhail Karasikov , Axel Lagré , Roman Moser , Joost van Doorn , Fei Tang

Scaling up model and data size have demonstrated impressive performance improvement over a wide range of tasks. Despite extensive studies on scaling behaviors for general-purpose tasks, medical images exhibit substantial differences from…

Computer Vision and Pattern Recognition · Computer Science 2025-05-15 Jiarun Liu , Hong-Yu Zhou , Weijian Huang , Hao Yang , Dongning Song , Tao Tan , Yong Liang , Shanshan Wang

Foundation vision encoders such as CLIP and DINOv2, trained on web-scale data, exhibit strong transfer performance across tasks and datasets. However, medical imaging foundation models remain constrained by smaller datasets, limiting our…

The development of radiology foundation models (RFMs) is hindered by a reliance on brute-force scaling. Existing approaches often directly translate methods for natural images, which prioritize scale over precision and hence lead to brittle…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Yingtai Li , Shuai Ming , Mingyue Zhao , Haoran Lai , Rongsheng Wang , Rui Zhou , Rundong Wang , Yujia Li , Wei Wei , Shaohua Kevin Zhou

Following its success for vision and text, the "foundation model" (FM) paradigm -- pretraining large models on massive data, then fine-tuning on target tasks -- has rapidly expanded to domains in the sciences, engineering, healthcare, and…

Machine Learning · Computer Science 2025-03-24 Zongzhe Xu , Ritvik Gupta , Wenduo Cheng , Alexander Shen , Junhong Shen , Ameet Talwalkar , Mikhail Khodak

Foundation models, large-scale, pre-trained deep-learning models adapted to a wide range of downstream tasks have gained significant interest lately in various deep-learning problems undergoing a paradigm shift with the rise of these…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Bobby Azad , Reza Azad , Sania Eskandari , Afshin Bozorgpour , Amirhossein Kazerouni , Islem Rekik , Dorit Merhof

Developing Foundation Models for medical image analysis is essential to overcome the unique challenges of radiological tasks. The first challenges of this kind for 3D brain MRI, SSL3D and FOMO25, were held at MICCAI 2025. Our solution…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Pedro M. Gordaliza , Jaume Banus , Benoît Gérin , Maxence Wynen , Nataliia Molchanova , Jonas Richiardi , Meritxell Bach Cuadra

Foundation models (FMs) have demonstrated strong transferability across medical imaging tasks, yet their clinical utility depends critically on how pretrained representations are adapted to domain-specific data, supervision regimes, and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

Head computed tomography (CT) imaging is a widely-used imaging modality with multitudes of medical indications, particularly in assessing pathology of the brain, skull, and cerebrovascular system. It is commonly the first-line imaging in…

The rapid proliferation of open-source medical foundation models (FMs) raises a practical question: how well do their pre-trained representations transfer to clinically relevant but data-scarce classification tasks? Particularly in CT-based…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Hartmut Häntze , Sarah de Boer , Myrthe Buser , Alessa Hering , Bram van Ginneken , Mathias Prokop , Jawed Nawabi , Sebastian Ziegelmayer , Lisa Adams , Keno Bressem

Recent advancements in artificial intelligence (AI), particularly foundation models (FMs), have revolutionized medical image analysis, demonstrating strong zero- and few-shot performance across diverse medical imaging tasks, from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Praveenbalaji Rajendran , Mojtaba Safari , Wenfeng He , Mingzhe Hu , Shansong Wang , Jun Zhou , Xiaofeng Yang

Pretraining with large-scale 3D volumes has a potential for improving the segmentation performance on a target medical image dataset where the training images and annotations are limited. Due to the high cost of acquiring pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Guotai Wang , Jianghao Wu , Xiangde Luo , Xinglong Liu , Kang Li , Shaoting Zhang

Foundation models (FMs) are rapidly reshaping medical imaging, shifting the field from narrowly trained, task-specific networks toward large, general-purpose models that can be adapted across modalities, anatomies, and clinical tasks. In…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Chuang Niu , Pengwei Wu , Bruno De Man , Ge Wang
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