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Image segmentation plays an essential role in medicine for both diagnostic and interventional tasks. Segmentation approaches are either manual, semi-automated or fully-automated. Manual segmentation offers full control over the quality of…

Computer Vision and Pattern Recognition · Computer Science 2019-03-21 Tomas Sakinis , Fausto Milletari , Holger Roth , Panagiotis Korfiatis , Petro Kostandy , Kenneth Philbrick , Zeynettin Akkus , Ziyue Xu , Daguang Xu , Bradley J. Erickson

Mammography images are widely used to detect non-palpable breast lesions or nodules, preventing cancer and providing the opportunity to plan interventions when necessary. The identification of some structures of interest is essential to…

Image and Video Processing · Electrical Eng. & Systems 2023-07-21 Cesar A. Sierra-Franco , Jan Hurtado , Victor de A. Thomaz , Leonardo C. da Cruz , Santiago V. Silva , Alberto B. Raposo

Prostate specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) imaging provides a tremendously exciting frontier in visualization of prostate cancer (PCa) metastatic lesions. However, accurate…

Medical Physics · Physics 2024-12-05 Amirhosein Toosi , Sara Harsini , François Bénard , Carlos Uribe , Arman Rahmim

Background: In the field of radiology and radiotherapy, accurate delineation of tissues and organs plays a crucial role in both diagnostics and therapeutics. While the gold standard remains expert-driven manual segmentation, many automatic…

Quantitative Methods · Quantitative Biology 2025-08-14 Szuzina Fazekas , Bettina Katalin Budai , Viktor Bérczi , Pál Maurovich-Horvat , Zsolt Vizi

Automatic and consistent meningioma segmentation in T1-weighted MRI volumes and corresponding volumetric assessment is of use for diagnosis, treatment planning, and tumor growth evaluation. In this paper, we optimized the segmentation and…

Image and Video Processing · Electrical Eng. & Systems 2021-09-24 David Bouget , André Pedersen , Sayied Abdol Mohieb Hosainey , Johanna Vanel , Ole Solheim , Ingerid Reinertsen

Histopathological image analysis is a reliable method for prostate cancer identification. In this paper, we present a comparative analysis of two approaches for segmenting glandular structures in prostate images to automate Gleason grading.…

Image and Video Processing · Electrical Eng. & Systems 2025-01-23 Feda Bolus Al Baqain , Omar Sultan Al-Kadi

Recently, joint registration and segmentation has been formulated in a deep learning setting, by the definition of joint loss functions. In this work, we investigate joining these tasks at the architectural level. We propose a registration…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Laurens Beljaards , Mohamed S. Elmahdy , Fons Verbeek , Marius Staring

Accurate segmentation of Pelvic Radiation Injury (PRI) from Magnetic Resonance Images (MRI) is crucial for more precise prognosis assessment and the development of personalized treatment plans. However, automated segmentation remains…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Xinyu Xiong , Wuteng Cao , Zihuang Wu , Lei Zhang , Chong Gao , Guanbin Li , Qiyuan Qin

The purpose was to assess the clinical value of a novel DropOut model for detecting and segmenting brain metastases, in which a neural network is trained on four distinct MRI sequences using an input dropout layer, thus simulating the…

Automated lesion segmentation in PET/CT scans is crucial for improving clinical workflows and advancing cancer diagnostics. However, the task is challenging due to physiological variability, different tracers used in PET imaging, and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Maximilian Rokuss , Balint Kovacs , Yannick Kirchhoff , Shuhan Xiao , Constantin Ulrich , Klaus H. Maier-Hein , Fabian Isensee

Cerebral microbleeds are small hypointense lesions visible on magnetic resonance imaging (MRI) with gradient echo, T2*, or susceptibility weighted (SWI) imaging. Assessment of cerebral microbleeds is mostly performed by visual inspection.…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Hugo J. Kuijf

Automatic segmentation of vestibular schwannoma (VS) tumors from magnetic resonance imaging (MRI) would facilitate efficient and accurate volume measurement to guide patient management and improve clinical workflow. The accuracy and…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Guotai Wang , Jonathan Shapey , Wenqi Li , Reuben Dorent , Alex Demitriadis , Sotirios Bisdas , Ian Paddick , Robert Bradford , Sebastien Ourselin , Tom Vercauteren

Many recent medical segmentation systems rely on powerful deep learning models to solve highly specific tasks. To maximize performance, it is standard practice to evaluate numerous pipelines with varying model topologies, optimization…

Machine Learning · Computer Science 2019-11-06 Mathias Perslev , Erik Bjørnager Dam , Akshay Pai , Christian Igel

Deep learning is expected to aid pathologists by automating tasks such as tumour segmentation. We aimed to develop one universal tumour segmentation model for histopathological images and examine its performance in different cancer types.…

We demonstrate automated segmentation of clear cell renal cell carcinomas (ccRCC), cysts, and surrounding normal kidney parenchyma in patients with von Hippel-Lindau (VHL) syndrome using convolutional neural networks (CNN) on Magnetic…

Organ at risk (OAR) segmentation is a crucial step for treatment planning and outcome determination in radiotherapy treatments of cancer patients. Several deep learning based segmentation algorithms have been developed in recent years,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-07 Ilkin Isler , Curtis Lisle , Justin Rineer , Patrick Kelly , Damla Turgut , Jacob Ricci , Ulas Bagci

Radiotherapy (RT) is a key component in the treatment of various cancers, including Acute Lymphocytic Leukemia (ALL) and Acute Myelogenous Leukemia (AML). Precise delineation of organs at risk (OARs) and target areas is essential for…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Ricardo Coimbra Brioso , Damiano Dei , Ciro Franzese , Nicola Lambri , Daniele Loiacono , Pietro Mancosu , Marta Scorsetti

Automatic lymph node (LN) segmentation and detection for cancer staging are critical. In clinical practice, computed tomography (CT) and positron emission tomography (PET) imaging detect abnormal LNs. Despite its low contrast and variety in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-23 Al-Akhir Nayan , Boonserm Kijsirikul , Yuji Iwahori

Blood oxygen level dependent (BOLD) MRI with maternal hyperoxia can assess oxygen transport within the placenta and has emerged as a promising tool to study placental function. Measuring signal changes over time requires segmenting the…

Image and Video Processing · Electrical Eng. & Systems 2022-08-08 S. Mazdak Abulnaga , Sean I. Young , Katherine Hobgood , Eileen Pan , Clinton J. Wang , P. Ellen Grant , Esra Abaci Turk , Polina Golland

Purpose: To develop a neural ordinary differential equation (ODE) model for visualizing deep neural network (DNN) behavior during multi-parametric MRI (mp-MRI) based glioma segmentation as a method to enhance deep learning explainability.…

Quantitative Methods · Quantitative Biology 2022-03-25 Zhenyu Yang , Zongsheng Hu , Hangjie Ji , Kyle Lafata , Scott Floyd , Fang-Fang Yin , Chunhao Wang
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