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In a regression analysis, suppose we suspect that there are several heterogeneous groups in the population that a sample represents. Mixture regression models have been applied to address such problems. By modeling the conditional…

Methodology · Statistics 2013-07-02 Toshiya Hoshikawa

In the context of multilevel longitudinal data, where sample units are collected in clusters, an important aspect that should be accounted for is the unobserved heterogeneity between sample units and between clusters. For this aim we…

Statistics Theory · Mathematics 2012-08-10 F. Bartolucci , M. Lupparelli

Dynamic event prediction, using joint modeling of survival time and longitudinal variables, is extremely useful in personalized medicine. However, the estimation of joint models including many longitudinal markers is still a computational…

Methodology · Statistics 2024-12-13 Reza Hashemi , Taban Baghfalaki , Viviane Philipps , Helene Jacqmin-Gadda

Technological advancements have enabled the recording of spiking activities from large neuron ensembles, presenting an exciting yet challenging opportunity for statistical analysis. This project considers the challenges from a common type…

Applications · Statistics 2024-04-05 Zitong Zhang , Shizhe Chen

Joint Models for longitudinal and time-to-event data have gained a lot of attention in the last few years as they are a helpful technique to approach common a data structure in clinical studies where longitudinal outcomes are recorded…

Long non-coding RNAs (lncRNAs) are emerging regulatory molecules implicated in chronic disease pathogenesis, including Type 2 Diabetes Mellitus (T2D). We investigated ten literature reported lncRNAs associated with T2D: MALAT1, MEG3, MIAT,…

Genomics · Quantitative Biology 2026-05-26 Ashwani Siwach , Sanjeev Narayan Sharma , Sunil Datt Sharma

Computer Vision practitioners must thoroughly understand their model's performance, but conditional evaluation is complex and error-prone. In biometric verification, model performance over continuous covariates---real-number attributes of…

Machine Learning · Computer Science 2020-09-22 Mel McCurrie , Hamish Nicholson , Walter J. Scheirer , Samuel Anthony

Joint models are well suited to modelling linked data from laboratories and health registers. However, there are few examples of joint models that allow for (a) multiple markers, (b) multiple survival outcomes (including terminal events,…

In medical time series disease diagnosis, two key challenges are identified.First, the high annotation cost of medical data leads to overfitting in models trained on label-limited, single-center datasets. To address this, we propose…

Machine Learning · Computer Science 2025-01-31 Yifan Wang , Hongfeng Ai , Ruiqi Li , Maowei Jiang , Cheng Jiang , Chenzhong Li

Variable selection naturally arises as a useful subject when faced with data with massive predictor space. In addition to the massive dimensionality, the data may be characterized by intra-subject correlation, and cure fraction, which are…

Methodology · Statistics 2025-12-24 Richard Tawiah , Shu Kay Ng , Geoffrey J. McLachlan

Preventable or undiagnosed visual impairment and blindness affect billion of people worldwide. Automated multi-disease detection models offer great potential to address this problem via clinical decision support in diagnosis. In this work,…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Dominik Müller , Iñaki Soto-Rey , Frank Kramer

In healthcare, patient data is often collected as multivariate time series, providing a comprehensive view of a patient's health status over time. While this data can be sparse, connected devices may enhance its frequency. The goal is to…

Machine Learning · Computer Science 2024-01-11 Violaine Courrier , Christophe Biernacki , Cristian Preda , Benjamin Vittrant

This study presents a semi-nonparametric Latent Class Choice Model (LCCM) with a flexible class membership component. The proposed model formulates the latent classes using mixture models as an alternative approach to the traditional random…

The complexity of linear mixed-effects (LME) models means that traditional diagnostics are rendered less effective. This is due to a breakdown of asymptotic results, boundary issues, and visible patterns in residual plots that are…

Methodology · Statistics 2016-12-08 Adam Loy , Heike Hofmann , Dianne Cook

As in other estimation scenarios, likelihood based estimation in the normal mixture set-up is highly non-robust against model misspecification and presence of outliers (apart from being an ill-posed optimization problem). A robust…

Methodology · Statistics 2023-12-20 Soumya Chakraborty , Ayanendranath Basu , Abhik Ghosh

Subspace clustering is to find underlying low-dimensional subspaces and cluster the data points correctly. In this paper, we propose a novel multi-view subspace clustering method. Most existing methods suffer from two critical issues.…

Artificial Intelligence · Computer Science 2022-05-24 Mengyuan Zhang , Kai Liu

The systematic collection of longitudinal data is very common in practice, making mixed models widely used. Most developments around these models focus on modeling the mean trajectory of repeated measurements, typically under the assumption…

Multi-view clustering methods have been a focus in recent years because of their superiority in clustering performance. However, typical traditional multi-view clustering algorithms still have shortcomings in some aspects, such as removal…

Machine Learning · Computer Science 2020-08-25 Junpeng Tan , Yukai Shi , Zhijing Yang , Caizhen Wen , Liang Lin

This paper introduces a prognostic method called FLASH that addresses the problem of joint modelling of longitudinal data and censored durations when a large number of both longitudinal and time-independent features are available. In the…

Longitudinal studies of a binary outcome are common in the health, social, and behavioral sciences. In general, a feature of random effects logistic regression models for longitudinal binary data is that the marginal functional form, when…