Related papers: Ontology-Aware Design Patterns for Clinical AI Sys…
Since the inception of Industry 4.0 in 2012, emerging technologies have enabled the acquisition of vast amounts of data from diverse sources such as machine tools, robust and affordable sensor systems with advanced information models, and…
Most clinical AI systems operate as prediction engines -- producing labels or risk scores -- yet real clinical reasoning is a time-bounded, sequential control problem under uncertainty. Clinicians interleave information gathering with…
Different domains foster different architectural styles -- and thus different documentation practices (e.g., state-based models for behavioral control vs. ER-style models for information structures). Agentic AI systems exhibit another…
Individuals and organizations cope with an always-growing amount of data, which is heterogeneous in its contents and formats. An adequate data management process yielding data quality and control over its lifecycle is a prerequisite to…
Explanations are crucial for building trustworthy AI systems, but a gap often exists between the explanations provided by models and those needed by users. To address this gap, we introduce MetaExplainer, a neuro-symbolic framework designed…
The importance of improving the FAIRness (findability, accessibility, interoperability, reusability) of research data is undeniable, especially in the face of large, complex datasets currently being produced by omics technologies.…
The incorporation of Artificial Intelligence (AI) models into various optimization systems is on the rise. Yet, addressing complex urban and environmental management problems normally requires in-depth domain science and informatics…
Our aim in this paper is to outline how the design space for the ontologization process is broader than current practice would suggest. We point out that engineering processes as well as products need to be designed and identify some…
The release of ChatGPT, Gemini, and other large language model has drawn huge interests on foundations models. There is a broad consensus that foundations models will be the fundamental building blocks for future AI systems. However, there…
Current large language models (LLMs) excel in verifiable domains where outputs can be checked before action but prove less reliable for high-stakes strategic decisions with uncertain outcomes. This gap, driven by mutually reinforcing…
In the following contribution, a method is introduced that integrates domain expert-centric ontology design with the Cross-Industry Standard Process for Data Mining (CRISP-DM). This approach aims to efficiently build an application-specific…
This paper explores the significant impact of AI-based medical devices, including wearables, telemedicine, large language models, and digital twins, on clinical decision support systems. It emphasizes the importance of producing outcomes…
Generative artificial intelligence (AI) is rapidly populating medical records with synthetic content, creating a feedback loop where future models are increasingly at risk of training on uncurated AI-generated data. However, the clinical…
Artificial Intelligence frameworks should allow for ever more autonomous and general systems in contrast to very narrow and restricted (human pre-defined) domain systems, in analogy to how the brain works. Self-constructive Artificial…
Data annotation is essential but highly error-prone in the development of AI-enabled perception systems (AIePS) for automated driving, and its quality directly influences model performance, safety, and reliability. However, the industry…
Reusing ontologies in practice is still very challenging, especially when multiple ontologies are (jointly) involved. Moreover, despite recent advances, the realization of systematic ontology quality assurance remains a difficult problem.…
This study analyzes hybrid AI systems' design patterns and their effectiveness in clinical decision-making using the boxology framework. It categorizes and copares various architectures combining machine learning and rule-based reasoning to…
The ever-increasing amount of data in biomedical research, and in cancer research in particular, needs to be managed to support efficient data access, exchange and integration. Existing software infrastructures, such caGrid, support access…
Artificial Intelligence (AI) tools for automating design artifact generation are increasingly used in Requirements Engineering (RE) to transform textual requirements into structured diagrams and models. While these AI tools, particularly…
Single-cell omics technologies have transformed our understanding of cellular diversity by enabling high-resolution profiling of individual cells. However, the unprecedented scale and heterogeneity of these datasets demand robust frameworks…