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The early signs of cognitive decline are often noticeable in conversational speech, and identifying those signs is crucial in dealing with later and more serious stages of neurodegenerative diseases. Clinical detection is costly and…

In the status quo, dementia is yet to be cured. Precise diagnosis prior to the onset of the symptoms can prevent the rapid progression of the emerging cognitive impairment. Recent progress has shown that Electroencephalography (EEG) is the…

Speech-based analysis offers a scalable and non-invasive approach for detecting cognitive decline, yet progress has been constrained by the limited availability of clinically validated datasets collected under realistic conditions. We…

Dementia, a progressive neurodegenerative disorder, affects memory, reasoning, and daily functioning, creating challenges for individuals and healthcare systems. Early detection is crucial for timely interventions that may slow disease…

Neurons and Cognition · Quantitative Biology 2025-03-04 Sahar Sinene Mehdoui , Abdelhamid Bouzid , Daniel Sierra-Sosa , Adel Elmaghraby

The global prevalence of dementia is projected to double by 2050, highlighting the urgent need for scalable diagnostic tools. This study utilizes digital cognitive tasks with eye-tracking data correlated with memory processes to distinguish…

Human-Computer Interaction · Computer Science 2025-08-28 Tomás Silva Santos Rocha , Anastasiia Mikhailova , Moreno I. Coco , José Santos-Victor

Recent progress has been made in detecting early stage dementia entirely through recordings of patient speech. Multimodal speech analysis methods were applied to the PROCESS challenge, which requires participants to use audio recordings of…

Audio and Speech Processing · Electrical Eng. & Systems 2025-02-14 Lei Chi , Arav Sharma , Ari Gebhardt , Joseph T. Colonel

This study investigates the potential of multimodal data integration, which combines electroencephalogram (EEG) data with sociodemographic characteristics like age, sex, education, and intelligence quotient (IQ), to diagnose mental diseases…

Machine Learning · Computer Science 2025-02-07 Himanshi Singh , Sadhana Tiwari , Sonali Agarwal , Ritesh Chandra , Sanjay Kumar Sonbhadra , Vrijendra Singh

Dementia is a neurodegenerative disorder that causes cognitive decline and affects more than 50 million people worldwide. Dementia is under-diagnosed by healthcare professionals - only one in four people who suffer from dementia are…

Modern clinical practice increasingly depends on reasoning over heterogeneous, evolving, and incomplete patient data. Although recent advances in multimodal foundation models have improved performance on various clinical tasks, most…

Early diagnosis of dementia, particularly in the prodromal stage (i.e., mild cognitive impairment, or MCI), has become a research and clinical priority but remains challenging. Automated analysis of the drawing process has been studied as a…

Signal Processing · Electrical Eng. & Systems 2022-11-17 Yasunori Yamada , Masatomo Kobayashi , Kaoru Shinkawa , Miyuki Nemoto , Miho Ota , Kiyotaka Nemoto , Tetsuaki Arai

While affective computing has advanced considerably, multimodal emotion prediction in aging populations remains underexplored, largely due to the scarcity of dedicated datasets. Existing multimodal benchmarks predominantly target young,…

Human-Computer Interaction · Computer Science 2026-04-06 Hongbin Chen , Jie Li , Wei Wang , Siyang Song , Xiao Gu , Jianqing Li , Wentao Xiang

Alzheimer's disease (AD) and its prodromal stage, Mild Cognitive Impairment (MCI), are associated with subtle declines in memory, attention, and language that often go undetected until late in progression. Traditional diagnostic tools such…

Human-Computer Interaction · Computer Science 2025-12-30 Ananya Drishti , Mahfuza Farooque

Mental disorders are among the foremost contributors to the global healthcare challenge. Research indicates that timely diagnosis and intervention are vital in treating various mental disorders. However, the early somatization symptoms of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Yichun Li , Shuanglin Li , Syed Mohsen Naqvi

Early detection of dementia is crucial to devise effective interventions. Comprehensive cognitive tests, while being the most accurate means of diagnosis, are long and tedious, thus limiting their applicability to a large population,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Anusha A. S. , Uma Ranjan , Medha Sharma , Siddharth Dutt

A significant number of people are suffering from cognitive impairment all over the world. Early detection of cognitive impairment is of great importance to both patients and caregivers. However, existing approaches have their shortages,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-10 Zixiang Fei , Erfu Yang , Leijian Yu , Xia Li , Huiyu Zhou , Wenju Zhou

Speech-based digital biomarkers represent a scalable, non-invasive frontier for the early identification of Mild Cognitive Impairment (MCI). However, the development of robust diagnostic models remains impeded by acute clinical data…

Computation and Language · Computer Science 2026-02-10 Rui Feng , Zhiyao Luo , Liuyu Wu , Wei Wang , Yuting Song , Yong Liu , Kok Pin Ng , Jianqing Li , Xingyao Wang

Dementia is a progressive neurological disorder that profoundly affects the daily lives of older adults, impairing abilities such as verbal communication and cognitive function. Early diagnosis is essential for enhancing both lifespan and…

Computational Engineering, Finance, and Science · Computer Science 2023-11-07 Kaiying Lin , Peter Washington

Dementia affects cognitive functions of adults, including memory, language, and behaviour. Standard diagnostic biomarkers such as MRI are costly, whilst neuropsychological tests suffer from sensitivity issues in detecting dementia onset.…

Computation and Language · Computer Science 2023-12-27 Dimitris Gkoumas , Bo Wang , Adam Tsakalidis , Maria Wolters , Arkaitz Zubiaga , Matthew Purver , Maria Liakata

Mental disorders, such as anxiety and depression, have become a global concern that affects people of all ages. Early detection and treatment are crucial to mitigate the negative effects these disorders can have on daily life. Although…

Computers and Society · Computer Science 2025-02-05 Jinghui Qin , Changsong Liu , Tianchi Tang , Dahuang Liu , Minghao Wang , Qianying Huang , Rumin Zhang

Cognitive impairments in older adults represent a significant public health concern, necessitating accurate diagnostic and monitoring strategies. In this study, the principal cognitive and neuropsychological evaluations employed for the…

Neurons and Cognition · Quantitative Biology 2024-02-23 Chuang Li , Rubing Lin , Yantong Liu , Yichen Wei
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