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Structural changes in retinal blood vessels are critical biomarkers for the onset and progression of glaucoma and other ocular diseases. However, current vessel segmentation approaches largely rely on supervised learning and extensive…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Cheng Huang , Weizheng Xie , Fan Gao , Yutong Liu , Ruoling Wu , Zeyu Han , Jingxi Qiu , Xiangxiang Wang , Zhenglin Yang , Hao Wang , Yongbin Yu

Retinal vessel segmentation is of great interest for diagnosis of retinal vascular diseases. To further improve the performance of vessel segmentation, we propose IterNet, a new model based on UNet, with the ability to find obscured details…

Image and Video Processing · Electrical Eng. & Systems 2019-12-13 Liangzhi Li , Manisha Verma , Yuta Nakashima , Hajime Nagahara , Ryo Kawasaki

Deep convolutional neural networks (CNNs) are state-of-the-art for semantic image segmentation, but typically require many labeled training samples. Obtaining 3D segmentations of medical images for supervised training is difficult and labor…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Zhenlin Xu , Marc Niethammer

The chorioallantoic membrane (CAM) model is a widely used in vivo platform for studying angiogenesis, especially in relation to tumor growth, drug delivery, and vascular biology.Since the topology and morphology of developing blood vessels…

Image and Video Processing · Electrical Eng. & Systems 2025-09-26 Pengwu Song , Zhiping Wang , Peng Yao , Liang Xu , Shuwei Shen , Pengfei Shao , Mingzhai Sun , Ronald X. Xu

Retinal vessel segmentation, as a principal nonintrusive diagnose method for ophthalmology diseases or diabetics, suffers from data scarcity due to requiring pixel-wise labels. In this paper, we proposed a convenient patch-based two-stage…

Image and Video Processing · Electrical Eng. & Systems 2019-06-21 Chengzhi Shi , Jihong Liu , Dali Chen

Deep convolutional neural networks (CNNs) have shown excellent performance in object recognition tasks and dense classification problems such as semantic segmentation. However, training deep neural networks on large and sparse datasets is…

Computer Vision and Pattern Recognition · Computer Science 2017-12-25 Lorenz Berger , Eoin Hyde , M. Jorge Cardoso , Sebastien Ourselin

In real-world visual recognition problems, the assumption that the training data (source domain) and test data (target domain) are sampled from the same distribution is often violated. This is known as the domain adaptation problem. In this…

Computer Vision and Pattern Recognition · Computer Science 2018-04-17 Hongyu Xu , Jingjing Zheng , Azadeh Alavi , Rama Chellappa

Retinal imaging has emerged as a promising method of addressing this challenge, taking advantage of the unique structure of the retina. The retina is an embryonic extension of the central nervous system, providing a direct in vivo window…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Syed Javed , Tariq M. Khan , Abdul Qayyum , Arcot Sowmya , Imran Razzak

Retinal vessel segmentation is a crucial step in diagnosing and screening various diseases, including diabetes, ophthalmologic diseases, and cardiovascular diseases. In this paper, we propose an effective and efficient method for vessel…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Zhun Fan , Jiajie Mo , Benzhang Qiu , Wenji Li , Guijie Zhu , Chong Li , Jianye Hu , Yibiao Rong , Xinjian Chen

Retinal diseases can cause irreversible vision loss in both eyes if not diagnosed and treated early. Since retinal diseases are so complicated, retinal imaging is likely to show two or more abnormalities. Current deep learning techniques…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Tariq M Khan , Shahzaib Iqbal , Syed S. Naqvi , Imran Razzak , Erik Meijering

Recent advances in Vision Transformers (ViTs) have significantly advanced semantic segmentation performance. However, their adaptation to new target domains remains challenged by distribution shifts, which often disrupt global attention…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Enming Zhang , Zhengyu Li , Yanru Wu , Jingge Wang , Yang Tan , Guan Wang , Yang Li , Xiaoping Zhang

State-of-the-art systems for semantic image segmentation use feed-forward pipelines with fixed computational costs. Building an image segmentation system that works across a range of computational budgets is challenging and time-intensive…

Computer Vision and Pattern Recognition · Computer Science 2018-03-16 Lane McIntosh , Niru Maheswaranathan , David Sussillo , Jonathon Shlens

Automatic segmentation of magnetic resonance (MR) images is crucial for morphological evaluation of the pediatric musculoskeletal system in clinical practice. However, the accuracy and generalization performance of individual segmentation…

Computer Vision and Pattern Recognition · Computer Science 2022-02-03 Arnaud Boutillon , Pierre-Henri Conze , Christelle Pons , Valérie Burdin , Bhushan Borotikar

Retinal vascular morphology is crucial for diagnosing diseases such as diabetes, glaucoma, and hypertension, making accurate segmentation of retinal vessels essential for early intervention. Traditional segmentation methods assume that…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Bo Liu , Yudong Zhang , Shuihua Wang , Siyue Li , Jin Hong

The retinal vasculature provides important clues in the diagnosis and monitoring of systemic diseases including hypertension and diabetes. The microvascular system is of primary involvement in such conditions, and the retina is the only…

Image and Video Processing · Electrical Eng. & Systems 2022-03-29 Ali Hatamizadeh , Hamid Hosseini , Niraj Patel , Jinseo Choi , Cameron C. Pole , Cory M. Hoeferlin , Steven D. Schwartz , Demetri Terzopoulos

For medical image analysis, segmentation models trained on one or several domains lack generalization ability to unseen domains due to discrepancies between different data acquisition policies. We argue that the degeneration in segmentation…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Ziqi Zhou , Lei Qi , Yinghuan Shi

The ability of neural networks to continuously learn and adapt to new tasks while retaining prior knowledge is crucial for many applications. However, current neural networks tend to forget previously learned tasks when trained on new ones,…

Computer Vision and Pattern Recognition · Computer Science 2020-05-04 Sinan Özgür Özgün , Anne-Marie Rickmann , Abhijit Guha Roy , Christian Wachinger

Variational Level Set (VLS) has been a widely used method in medical segmentation. However, segmentation accuracy in the VLS method dramatically decreases when dealing with intervening factors such as lighting, shadows, colors, etc.…

Computer Vision and Pattern Recognition · Computer Science 2018-10-12 T. Hoang Ngan Le , Raajitha Gummadi , Marios Savvides

High fidelity segmentation of both macro and microvascular structure of the retina plays a pivotal role in determining degenerative retinal diseases, yet it is a difficult problem. Due to successive resolution loss in the encoding phase…

Image and Video Processing · Electrical Eng. & Systems 2021-10-20 Sharif Amit Kamran , Khondker Fariha Hossain , Alireza Tavakkoli , Stewart Lee Zuckerbrod , Kenton M. Sanders , Salah A. Baker

Automated surface segmentation is important and challenging in many medical image analysis applications. Recent deep learning based methods have been developed for various object segmentation tasks. Most of them are a classification based…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Leixin Zhou , Xiaodong Wu