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Speech-based depression detection tools could aid early screening. Here, we propose an interpretable speech foundation model approach to enhance the clinical applicability of such tools. We introduce a speech-level Audio Spectrogram…

Sound · Computer Science 2026-03-26 Qingkun Deng , Saturnino Luz , Sofia de la Fuente Garcia

Automatic depression detection using speech signals with acoustic and textual modalities is a promising approach for early diagnosis. Depression-related patterns exhibit sparsity in speech: diagnostically relevant features occur in specific…

Sound · Computer Science 2026-04-14 Hangbin Yu , Yudong Yang , Rongfeng Su , Nan Yan , Lan Wang

Dementia is a group of irreversible, chronic, and progressive neurodegenerative disorders resulting in impaired memory, communication, and thought processes. In recent years, clinical research advances in brain aging have focused on the…

Computation and Language · Computer Science 2021-02-25 Swati Padhee , Anurag Illendula , Megan Sadler , Valerie L. Shalin , Tanvi Banerjee , Krishnaprasad Thirunarayan , William L. Romine

Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

Neurons and Cognition · Quantitative Biology 2025-04-24 Zhenguang Zhong , Zhixuan Wang

Speech is a scalable and non-invasive biomarker for early mental health screening. However, widely used depression datasets like DAIC-WOZ exhibit strong coupling between linguistic sentiment and diagnostic labels, encouraging models to…

Computation and Language · Computer Science 2026-01-05 Yuxin Li , Xiangyu Zhang , Yifei Li , Zhiwei Guo , Haoyang Zhang , Eng Siong Chng , Cuntai Guan

Speech patterns have been identified as potential diagnostic markers for neuropsychiatric conditions. However, most studies only compare a single clinical group to healthy controls, whereas clinical practice often requires differentiating…

This paper proposes a speech-based method for automatic depression classification. The system is based on ensemble learning for Convolutional Neural Networks (CNNs) and is evaluated using the data and the experimental protocol provided in…

Audio and Speech Processing · Electrical Eng. & Systems 2024-02-06 Adrián Vázquez-Romero , Ascensión Gallardo-Antolín

This study investigates whether speech-based depression detection models learn depression-related acoustic biomarkers or instead rely on speaker identity cues. Using the DAIC-WOZ dataset, we propose a data-splitting strategy that controls…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-17 Hsiang-Chen Yeh , Luqi Sun , Aurosweta Mahapatra , Shreeram Suresh Chandra , Emily Mower Provost , Berrak Sisman

Depression is a global mental health problem, the worst case of which can lead to suicide. An automatic depression detection system provides great help in facilitating depression self-assessment and improving diagnostic accuracy. In this…

Audio and Speech Processing · Electrical Eng. & Systems 2022-02-17 Ying Shen , Huiyu Yang , Lin Lin

Depression, a prevalent mental health disorder impacting millions globally, demands reliable assessment systems. Unlike previous studies that focus solely on either detecting depression or predicting its severity, our work identifies…

Depression has been a leading cause of mental-health illnesses across the world. While the loss of lives due to unmanaged depression is a subject of attention, so is the lack of diagnostic tests and subjectivity involved. Using behavioural…

Artificial Intelligence · Computer Science 2020-10-07 Shivani Shimpi , Shyam Thombre , Snehal Reddy , Ritik Sharma , Srijan Singh

The aging society urgently requires scalable methods to monitor cognitive decline and identify social and psychological factors indicative of dementia risk in older adults. Our machine learning (ML) models captured facial, acoustic,…

Automatic speech recognition (ASR) technology can aid in the detection, monitoring, and assessment of depressive symptoms in individuals. ASR systems have been used as a tool to analyze speech patterns and characteristics that are…

Human-Computer Interaction · Computer Science 2023-08-17 Alice Othmani , Muhammad Muzammel

Current approaches to detecting depression and anxiety from speech primarily rely on machine learning techniques that utilize hand-engineered paralinguistic features and related acoustic descriptors derived from time- and frequency-domain…

Machine Learning · Computer Science 2026-05-12 Oleksii Abramenko , Noah D. Stein , Colin Vaz

This study investigates clinicians' perceptions and attitudes toward an assistive artificial intelligence (AI) system that employs a speech-based explainable ML algorithm for detecting depression. The AI system detects depression from…

Human-Computer Interaction · Computer Science 2024-10-25 Kexin Feng , Theodora Chaspari

With more than 300 million people depressed worldwide, depression is a global problem. Due to access barriers such as social stigma, cost, and treatment availability, 60% of mentally-ill adults do not receive any mental health services.…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Albert Haque , Michelle Guo , Adam S Miner , Li Fei-Fei

Depression is a common mental disorder. Automatic depression detection tools using speech, enabled by machine learning, help early screening of depression. This paper addresses two limitations that may hinder the clinical implementations of…

Computation and Language · Computer Science 2023-10-09 Qingkun Deng , Saturnino Luz , Sofia de la Fuente Garcia

Predicting the presence of major depressive disorder (MDD) using behavioural and cognitive signals is a highly non-trivial task. The heterogeneous clinical profile of MDD means that any given speech, facial expression and/or observed…

Machine Learning · Computer Science 2023-06-26 Salvatore Fara , Orlaith Hickey , Alexandra Georgescu , Stefano Goria , Emilia Molimpakis , Nicholas Cummins

Recent progress has been made in detecting early stage dementia entirely through recordings of patient speech. Multimodal speech analysis methods were applied to the PROCESS challenge, which requires participants to use audio recordings of…

Audio and Speech Processing · Electrical Eng. & Systems 2025-02-14 Lei Chi , Arav Sharma , Ari Gebhardt , Joseph T. Colonel

We present a novel benchmark dataset and prediction tasks for investigating approaches to assess cognitive function through analysis of connected speech. The dataset consists of speech samples and clinical information for speakers of…