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Artificial intelligence (AI) is expected to revolutionize the practice of medicine. Recent advancements in the field of deep learning have demonstrated success in a variety of clinical tasks: detecting diabetic retinopathy from images,…

Machine Learning · Computer Science 2025-04-04 Joshua Hatherley

Instances of Artificial Intelligence (AI) systems failing to deliver consistent, satisfactory performance are legion. We investigate why AI failures occur. We address only a narrow subset of the broader field of AI Safety. We focus on AI…

Computers and Society · Computer Science 2020-08-11 Debarag Narayan Banerjee , Sasanka Sekhar Chanda

Artificial intelligence (AI) is increasingly integrated into modern healthcare, offering powerful support for clinical decision-making. However, in real-world settings, AI systems may experience performance degradation over time, due to…

Artificial Intelligence · Computer Science 2026-02-05 Hao Guan , David Bates , Li Zhou

This paper examines how pharmaceutical Artificial Intelligence advancements may affect the development of new drugs in the coming years. The question was answered by reviewing a rich body of source material, including industry literature,…

Computers and Society · Computer Science 2021-07-09 Adam Zielinski

Artificial Intelligence (AI) is increasingly employed to enhance assistive technologies, yet it can fail in various ways. We conducted a systematic literature review of research into AI-based assistive technology for persons with visual…

Human-Computer Interaction · Computer Science 2024-07-22 Zahra Ahmadi , Peter R. Lewis , Mahadeo A. Sukhai

AI-based systems have been used widely across various industries for different decisions ranging from operational decisions to tactical and strategic ones in low- and high-stakes contexts. Gradually the weaknesses and issues of these…

Human-Computer Interaction · Computer Science 2022-01-13 Morteza Saberi

As AI technologies increase in capability and ubiquity, AI accidents are becoming more common. Based on normal accident theory, high reliability theory, and open systems theory, we create a framework for understanding the risks associated…

Computers and Society · Computer Science 2024-03-13 Heather M. Williams , Roman V. Yampolskiy

Introduction: Artificial intelligence (AI) is exhibiting tremendous potential to reduce the massive costs and long timescales of drug discovery. There are however important challenges currently limiting the impact and scope of AI models.…

Other Quantitative Biology · Quantitative Biology 2024-09-25 Ghita Ghislat , Saiveth Hernandez-Hernandez , Chayanit Piyawajanusorn , Pedro J. Ballester

Artificial intelligence (AI) is rapidly advancing in healthcare, enhancing the efficiency and effectiveness of services across various specialties, including cardiology, ophthalmology, dermatology, emergency medicine, etc. AI applications…

AI systems are often introduced with high expectations, yet many fail to deliver, resulting in unintended harm and missed opportunities for benefit. We frequently observe significant "AI Mismatches", where the system's actual performance…

Human-Computer Interaction · Computer Science 2025-04-16 Devansh Saxena , Ji-Youn Jung , Jodi Forlizzi , Kenneth Holstein , John Zimmerman

Artificial intelligence (AI) holds great promise for supporting clinical trials, from patient recruitment and endpoint assessment to treatment response prediction. However, deploying AI without safeguards poses significant risks,…

Machine Learning · Computer Science 2025-10-09 Yao Chen , David Ohlssen , Aimee Readie , Gregory Ligozio , Ruvie Martin , Thibaud Coroller

Powerful predictive AI systems have demonstrated great potential in augmenting human decision making. Recent empirical work has argued that the vision for optimal human-AI collaboration requires 'appropriate reliance' of humans on AI…

Artificial Intelligence · Computer Science 2024-09-24 Gaole He , Abri Bharos , Ujwal Gadiraju

AI services are known to have unstable behavior when subjected to changes in data, models or users. Such behaviors, whether triggered by omission or commission, lead to trust issues when AI works with humans. The current approach of…

Human-Computer Interaction · Computer Science 2023-02-21 Biplav Srivastava , Kausik Lakkaraju , Mariana Bernagozzi , Marco Valtorta

AI is being increasingly used to aid response efforts to humanitarian emergencies at multiple levels of decision-making. Such AI systems are generally understood to be stand-alone tools for decision support, with ethical assessments,…

Computers and Society · Computer Science 2022-09-23 Joseph Aylett-Bullock , Miguel Luengo-Oroz

Risks associated with the use of AI, ranging from algorithmic bias to model hallucinations, have received much attention and extensive research across the AI community, from researchers to end-users. However, a gap exists in the systematic…

Artificial Intelligence · Computer Science 2025-11-21 Raymond K. Sheh , Karen Geappen

The use of Artificial Intelligence (AI), or more generally data-driven algorithms, has become ubiquitous in today's society. Yet, in many cases and especially when stakes are high, humans still make final decisions. The critical question,…

Artificial Intelligence · Computer Science 2024-10-15 Eli Ben-Michael , D. James Greiner , Melody Huang , Kosuke Imai , Zhichao Jiang , Sooahn Shin

Artificial intelligence (AI) is increasingly of tremendous interest in the medical field. However, failures of medical AI could have serious consequences for both clinical outcomes and the patient experience. These consequences could erode…

Artificial Intelligence · Computer Science 2020-08-19 Thomas P. Quinn , Manisha Senadeera , Stephan Jacobs , Simon Coghlan , Vuong Le

The use of AI in healthcare is designed to improve care delivery and augment the decisions of providers to enhance patient outcomes. When deployed in clinical settings, the interaction between providers and AI is a critical component for…

Human-Computer Interaction · Computer Science 2023-02-23 Ally Salim , Megan Allen , Kelvin Mariki , Kevin James Masoy , Jafary Liana

Artificial Intelligence (AI) technology epitomizes the complex challenges posed by human-made artifacts, particularly those widely integrated into society and exerting significant influence, highlighting potential benefits and their…

Artificial Intelligence · Computer Science 2025-10-06 Michael Papademas , Xenia Ziouvelou , Antonis Troumpoukis , Vangelis Karkaletsis

Artificial Intelligence (AI) is poised to transform healthcare delivery through revolutionary advances in clinical decision support and diagnostic capabilities. While human expertise remains foundational to medical practice, AI-powered…

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