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Quantum computing is moving beyond its early stage and seeking for commercial applications in chemical and biomedical sciences. In the current noisy intermediate-scale quantum computing era, quantum resource is too scarce to support these…

Quantum Physics · Physics 2023-03-08 Honghui Shang , Yi Fan , Li Shen , Chu Guo , Jie Liu , Xiaohui Duan , Fang Li , Zhenyu Li

Quantum computing holds promise for revolutionizing computational chemistry simulations, particularly in drug discovery. However, current quantum hardware is limited by noise and scale, necessitating bridging technologies. This study…

Quantum Physics · Physics 2025-04-16 Marek Kowalik , Ellen Michael , Peter Pogány , Phalgun Lolur

Quantum chemistry and materials science are among the most promising areas for demonstrating algorithmic quantum advantage and quantum utility due to their inherent quantum mechanical nature. Still, large-scale simulations of quantum…

Quantum Computing allows, in principle, the encoding of the exponentially scaling many-electron wave function onto a linearly scaling qubit register, offering a promising solution to overcome the limitations of traditional quantum chemistry…

Quantum Physics · Physics 2025-10-21 C. Feniou , O. Adjoua , B. Claudon , J. Zylberman , E. Giner , J. -P. Piquemal

Advances in quantum simulator technology is increasingly required because research on quantum algorithms is becoming more sophisticated and complex. State vector simulation utilizes CPU and memory resources in computing nodes exponentially…

Quantum Physics · Physics 2024-09-04 Mikio Morita , Yoshinori Tomita , Junpei Koyama , Koichi Kimura

In recent years, there has been a growing interest in the development of quantum emulation. However, existing studies often struggle to achieve broad applicability, high performance, and efficient resource and memory utilization. To address…

Quantum Physics · Physics 2025-11-06 Tran Van Duy , Tuan Hai Vu , Vu Trung Duong Le , Hoai Luan Pham , Yasuhiko Nakashima

Classical simulation of quantum circuits remains indispensable for algorithm development, hardware validation, and error analysis in the noisy intermediate-scale quantum (NISQ) era. However, state-vector simulation faces exponential memory…

High-Performance Computing (HPC) systems are the most powerful tools that we currently have to solve complex scientific simulations. Quantum computing (QC) has the potential to enhance HPC systems by accelerating the execution of specific…

Quantum computing has recently exhibited great potentials in predicting chemical properties for various applications in drug discovery, material design, and catalyst optimization. Progress has been made in simulating small molecules, such…

Quantum computational chemistry (QCC) is the use of quantum computers to solve problems in computational quantum chemistry. We develop a high performance variational quantum eigensolver (VQE) simulator for simulating quantum computational…

Many promising quantum applications depend on the efficient quantum simulation of an exponentially large sparse Hamiltonian, a task known as sparse Hamiltonian simulation, which is fundamentally important in quantum computation. Although…

Quantum Physics · Physics 2025-09-16 Jiaqi Leng , Joseph Li , Yuxiang Peng , Xiaodi Wu

Quantum computing enables parallelism through superposition and entanglement and offers advantages over classical computing architectures. However, due to the limitations of current quantum hardware in the noisy intermediate-scale quantum…

Quantum Physics · Physics 2025-09-09 Guolong Zhong , Yi Fan , Zhenyu Li

LLMs are increasingly executed in edge where limited GPU memory and heterogeneous computation jointly constrain deployment which motivates model partitioning and request scheduling. In this setting, minimizing latency requires addressing…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-02 Mulei Ma , Xinyi Xu , Minrui Xu , Zihan Chen , Yang Yang , Tony Q. S. Quek

As quantum computers of non-trivial size become available in the near future, it is imperative to develop tools to emulate small quantum computers. This allows for validation and debugging of algorithms as well as exploring…

Quantum Physics · Physics 2018-01-24 Thomas Häner , Damian S. Steiger , Mikhail Smelyanskiy , Matthias Troyer

Variational quantum eigensolvers are touted as a near-term algorithm capable of impacting many applications. However, the potential has not yet been realized, with few claims of quantum advantage and high resource estimates, especially due…

The abundant demand for deep learning compute resources has created a renaissance in low precision hardware. Going forward, it will be essential for simulation software to run on this new generation of machines without sacrificing…

Chemical Physics · Physics 2024-10-23 William Dawson , Katsuhisa Ozaki , Jens Domke , Takahito Nakajima

Simulating molecular systems on quantum computers requires efficient mappings from Fermionic operators to qubit operators. Traditional mappings such as Jordan-Wigner or Bravyi-Kitaev often produce high-weight Pauli terms, increasing circuit…

Quantum Physics · Physics 2025-11-13 James Brown , Tarini S Hardikar , Kenny Heitritter , Kanav Setia

We present a framework for effectively simulating the execution of quantum circuits originally designed to demonstrate quantum supremacy using accessible high-performance computing (HPC) infrastructure. Building on prior CPU-only…

Quantum Physics · Physics 2025-12-09 Bob Wold , Venkateswaran Kasirajan

We introduce a parallel, GPU-accelerated implementation of the iterative qubit coupled cluster (iQCC) method that overcomes the exponential growth of the transformed Hamiltonian -- the principal bottleneck for classical emulation of quantum…

Quantum Physics · Physics 2026-03-11 Seyyed Mehdi Hosseini Jenab , Brandon Henderson , Scott N. Genin

Quantum computers are promising powerful computers for solving complex problems, but access to real quantum hardware remains limited due to high costs. Although the software simulators on CPUs/GPUs such as Qiskit, ProjectQ, and Qsun offer…

Quantum Physics · Physics 2025-03-19 Tuan Hai Vu , Vu Trung Duong Le , Hoai Luan Pham , Quoc Chuong Nguyen , Yasuhiko Nakashima
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