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Large language models (LLMs) have achieved remarkable performance on various natural language tasks. However, they are trained on static corpora and their knowledge can become outdated quickly in the fast-changing world. This motivates the…

Computation and Language · Computer Science 2025-05-29 Tianci Liu , Ruirui Li , Zihan Dong , Hui Liu , Xianfeng Tang , Qingyu Yin , Linjun Zhang , Haoyu Wang , Jing Gao

Accurate heterogeneous treatment effect (HTE) estimation is essential for personalized recommendations, making it important to evaluate and compare HTE estimators. Traditional assessment methods are inapplicable due to missing…

Methodology · Statistics 2024-12-30 Zijun Gao

Estimating causal quantities from observational data is crucial for understanding the safety and effectiveness of medical treatments. However, to make reliable inferences, medical practitioners require not only estimating averaged causal…

Machine Learning · Computer Science 2026-03-13 Valentyn Melnychuk , Stefan Feuerriegel , Mihaela van der Schaar

Heterogeneous treatment effects (HTE) based on patients' genetic or clinical factors are of significant interest to precision medicine. Simultaneously modeling HTE and corresponding main effects for randomized clinical trials with…

Machine Learning · Statistics 2023-02-06 Heng Chen , Michael L. LeBlanc , James Y. Dai

Learning rate configuration is a fundamental aspect of modern deep learning. The prevailing practice of applying a uniform learning rate across all layers overlooks the structural heterogeneity of Transformers, potentially limiting their…

Machine Learning · Computer Science 2026-05-28 Di He , Songjun Tu , Keyu Wang , Lu Yin , Shiwei Liu

Estimating the conditional average treatment effect (CATE) from observational data is relevant for many applications such as personalized medicine. Here, we focus on the widespread setting where the observational data come from multiple…

Machine Learning · Computer Science 2024-06-05 Jonas Schweisthal , Dennis Frauen , Mihaela van der Schaar , Stefan Feuerriegel

Methods for estimating heterogeneous treatment effect in observational data have largely focused on continuous or binary outcomes, and have been relatively less vetted with survival outcomes. Using flexible machine learning methods in the…

Applications · Statistics 2021-07-09 Liangyuan Hu , Jiayi Ji , Fan Li

We study clustered multitask learning in a semiparametric setting where tasks share a latent cluster structure in their target parameters but exhibit heterogeneous, potentially infinite-dimensional nuisance components. Such heterogeneity…

Machine Learning · Statistics 2026-05-05 Hanxiao Chen , Debarghya Mukherjee

We study the assessment of the accuracy of heterogeneous treatment effect (HTE) estimation, where the HTE is not directly observable so standard computation of prediction errors is not applicable. To tackle the difficulty, we propose an…

Methodology · Statistics 2020-03-10 Zijun Gao , Trevor Hastie , Robert Tibshirani

Orthogonal statistical learning and double machine learning have emerged as general frameworks for two-stage statistical prediction in the presence of a nuisance component. We establish non-asymptotic bounds on the excess risk of orthogonal…

Machine Learning · Statistics 2022-06-22 Lang Liu , Carlos Cinelli , Zaid Harchaoui

Multi-view learning has progressed rapidly in recent years. Although many previous studies assume that each instance appears in all views, it is common in real-world applications for instances to be missing from some views, resulting in…

Machine Learning · Computer Science 2022-08-30 Pengfei Zhu , Xinjie Yao , Yu Wang , Meng Cao , Binyuan Hui , Shuai Zhao , Qinghua Hu

Analyses of heterogeneous treatment effects (HTE) are common in applied causal inference research. However, when outcomes are latent variables assessed via psychometric instruments such as educational tests, standard methods ignore the…

Transfer learning has been demonstrated to be successful and essential in diverse applications, which transfers knowledge from related but different source domains to the target domain. Online transfer learning(OTL) is a more challenging…

Machine Learning · Computer Science 2020-02-12 Yuntao Du , Zhiwen Tan , Qian Chen , Yi Zhang , Chongjun Wang

Meta-analyses of observational studies often show substantial between-study heterogeneity, limiting the interpretability of pooled estimates. Meta-regression can be used to explore heterogeneity, but it is often underpowered to handle…

Methodology · Statistics 2026-05-29 Kanella Panagiotopoulou , Theodoros Evrenoglou

In recent years, there has been growing interest in causal machine learning estimators for quantifying subject-specific effects of a binary treatment on time-to-event outcomes. Estimation approaches have been proposed which attenuate the…

Methodology · Statistics 2026-03-30 Matthew Pryce , Karla Diaz-Ordaz , Ruth H. Keogh , Stijn Vansteelandt

We consider Heterogeneous Transfer Learning (HTL) from a source to a new target domain for high-dimensional regression with differing feature sets. Most homogeneous TL methods assume that target and source domains share the same feature…

Machine Learning · Statistics 2025-12-02 Jae Ho Chang , Massimiliano Russo , Subhadeep Paul

Offline reinforcement learning is important in many settings with available observational data but the inability to deploy new policies online due to safety, cost, and other concerns. Many recent advances in causal inference and machine…

Machine Learning · Statistics 2025-07-08 Defu Cao , Angela Zhou

Estimating heterogeneous treatment effect is an important task in causal inference with wide application fields. It has also attracted increasing attention from machine learning community in recent years. In this work, we reinterpret the…

Methodology · Statistics 2018-10-26 Ran Chen , Hanzhong Liu

The increasing scientific attention given to precision medicine based on real-world data has led many recent studies to clarify the relationships between treatment effects and patient characteristics. However, this is challenging because of…

Methodology · Statistics 2022-06-20 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

Enforcing orthonormal or isometric property for the weight matrices has been shown to enhance the training of deep neural networks by mitigating gradient exploding/vanishing and increasing the robustness of the learned networks. However,…

Machine Learning · Computer Science 2024-03-01 Zhen Qin , Xuwei Tan , Zhihui Zhu