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Predicting how cells respond to genetic perturbations is fundamental to understanding gene function, disease mechanisms, and therapeutic development. While recent deep learning approaches have shown promise in modeling single-cell…

Machine Learning · Computer Science 2026-03-10 Andrea Giuseppe Di Francesco , Andrea Rubbi , Pietro Liò

Monitoring the integrity of elastic structures using ultrasonic waves requires the efficient identification of material parameters from measured surface displacements. The displacement field is governed by Cauchy's equation of motion, i.e.,…

Numerical Analysis · Mathematics 2026-05-20 Benedikt Klein , Mario Ohlberger , Thomas Schuster

Imbalanced classification and spurious correlation are common challenges in data science and machine learning. Both issues are linked to data imbalance, with certain groups of data samples significantly underrepresented, which in turn would…

Machine Learning · Statistics 2026-02-10 Ryumei Nakada , Yichen Xu , Lexin Li , Linjun Zhang

Parallel imaging techniques reduce magnetic resonance imaging (MRI) scan time but image quality degrades as the acceleration factor increases. In clinical practice, conservative acceleration factors are chosen because no mechanism exists to…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Ilias I. Giannakopoulos , Lokesh B Gautham Muthukumar , Yvonne W. Lui , Riccardo Lattanzi

With the rapid advancement of decentralized applications, smart contract security faces severe challenges, particularly regarding atomicity violations in complex logic such as Oracle and NFT contracts. Rigid rule sets often limit…

Cryptography and Security · Computer Science 2026-04-14 Xiaoqi Li , Xin Wang , Wenkai Li , Zongwei Li

In medical imaging, chromosome straightening plays a significant role in the pathological study of chromosomes and in the development of cytogenetic maps. Whereas different approaches exist for the straightening task, typically geometric…

Computer Vision and Pattern Recognition · Computer Science 2021-10-20 Sifan Song , Daiyun Huang , Yalun Hu , Chunxiao Yang , Jia Meng , Fei Ma , Frans Coenen , Jiaming Zhang , Jionglong Su

Detecting trajectory anomalies is a vital task in modern Intelligent Transportation Systems (ITS), enabling the identification of unsafe, inefficient, or irregular travel behaviours. While deep learning has emerged as the dominant approach,…

Machine Learning · Computer Science 2025-11-24 Rui Xue , Dan He , Fengmei Jin , Chen Zhang , Xiaofang Zhou

Fault diagnosis plays an essential role in reducing the maintenance costs of rotating machinery manufacturing systems. In many real applications of fault detection and diagnosis, data tend to be imbalanced, meaning that the number of…

Machine Learning · Computer Science 2022-03-30 Masoud Jalayer , Amin Kaboli , Carlotta Orsenigo , Carlo Vercellis

Industrial anomaly detection is a challenging open-set task that aims to identify unknown anomalous patterns deviating from normal data distribution. To avoid the significant memory consumption and limited generalizability brought by…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Qishan Wang , Haofeng Wang , Shuyong Gao , Jia Guo , Li Xiong , Jiaqi Li , Dengxuan Bai , Wenqiang Zhang

Time-domain astronomy is progressing rapidly with the ongoing and upcoming large-scale photometric sky surveys led by the Vera C. Rubin Observatory project (LSST). Billions of variable sources call for better automatic classification…

Instrumentation and Methods for Astrophysics · Physics 2023-09-26 Zihan Kang , Yanxia Zhang , Jingyi Zhang , Changhua Li , Minzhi Kong , Yongheng Zhao , Xue-Bing Wu

With the rapid development of neural network applications in NLP, model robustness problem is gaining more attention. Different from computer vision, the discrete nature of texts makes it more challenging to explore robustness in NLP.…

Computation and Language · Computer Science 2023-10-16 Linyang Li , Ke Ren , Yunfan Shao , Pengyu Wang , Xipeng Qiu

Deep sparse auto-encoders with mixed structure regularization (MSR) in addition to explicit sparsity regularization term and stochastic corruption of the input data with Gaussian noise have the potential to improve unsupervised abnormality…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Moti Freiman , Ravindra Manjeshwar , Liran Goshen

Significant challenges exist in efficient data analysis of most advanced experimental and observational techniques because the collected signals often include unwanted contributions--such as background and signal distortions--that can…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Yuan Ni , Zhantao Chen , Alexander N. Petsch , Edmund Xu , Cheng Peng , Alexander I. Kolesnikov , Sugata Chowdhury , Arun Bansil , Jana B. Thayer , Joshua J. Turner

Supervised deep learning techniques show promise in medical image analysis. However, they require comprehensive annotated data sets, which poses challenges, particularly for rare diseases. Consequently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Finn Behrendt , Debayan Bhattacharya , Lennart Maack , Julia Krüger , Roland Opfer , Robin Mieling , Alexander Schlaefer

Virtual cell modeling predicts molecular state changes under genetic perturbations in silico, which is essential for biological mechanism studies. However, existing approaches suffer from unconstrained reasoning, uninterpretable…

Quantitative Methods · Quantitative Biology 2026-04-23 Zhenyu Wang , Geyan Ye , Wei Liu , Man Tat Alexander Ng

In functional MRI (fMRI), faster acquisition via undersampling of data can improve the spatial-temporal resolution trade-off and increase statistical robustness through increased degrees-of-freedom. High quality reconstruction of fMRI data…

Medical Physics · Physics 2018-02-07 Lior Weizman , Karla L. Miller , Mark Chiew , Yonina C. Eldar

Reconstruction method based on the memory module for visual anomaly detection attempts to narrow the reconstruction error for normal samples while enlarging it for anomalous samples. Unfortunately, the existing memory module is not fully…

Computer Vision and Pattern Recognition · Computer Science 2022-09-27 Peng Xing , Zechao Li

Recent Blind Image Super-Resolution (BSR) methods have shown proficiency in general images. However, we find that the efficacy of recent methods obviously diminishes when employed on image data with blur, while image data with intentional…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Rui Qin , Ming Sun , Chao Zhou , Bin Wang

A new approach to maximum likelihood learning of discrete graphical models and RBM in particular is introduced. Our method, Perturb and Descend (PD) is inspired by two ideas (I) perturb and MAP method for sampling (II) learning by…

Neural and Evolutionary Computing · Computer Science 2014-05-08 Siamak Ravanbakhsh , Russell Greiner , Brendan Frey

Reconstructing PDE-governed fields from sparse and irregular measurements is challenging due to their ill-posed nature. Deterministic surrogates are trained on dense fields that struggle with limited measurements and uncertainty…

Machine Learning · Computer Science 2026-05-18 Hao Zhou , Rui Zhang , Han Wan , Hao Sun