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When simulating metabolite productions with genome-scale constraint-based metabolic models, gene deletion strategies are necessary to achieve growth-coupled production, which means cell growth and target metabolite production occur…

Quantitative Methods · Quantitative Biology 2025-11-18 Ziwei Yang , Takeyuki Tamura

We propose TD-GEN, a graph generation framework based on tree decomposition, and introduce a reduced upper bound on the maximum number of decisions needed for graph generation. The framework includes a permutation invariant tree generation…

Machine Learning · Computer Science 2022-02-24 Hamed Shirzad , Hossein Hajimirsadeghi , Amir H. Abdi , Greg Mori

Flight diversions are rare but high-impact events in aviation, making their reliable prediction vital for both safety and operational efficiency. However, their scarcity in historical records impedes the training of machine learning models…

Machine Learning · Computer Science 2026-04-23 Karim Aly , Alexei Sharpanskykh , Jacco Hoekstra

Effective trajectory generation is essential for reliable on-board spacecraft autonomy. Among other approaches, learning-based warm-starting represents an appealing paradigm for solving the trajectory generation problem, effectively…

Data-driven evolutionary multi-objective optimization (EMO) has been recognized as an effective approach for multi-objective optimization problems with expensive objective functions. The current research is mainly developed for problems…

Neural and Evolutionary Computing · Computer Science 2022-05-31 Renzhi Chen , Ke Li

Recent advancements in graph representation learning have shifted attention towards dynamic graphs, which exhibit evolving topologies and features over time. The increased use of such graphs creates a paramount need for generative models…

Machine Learning · Computer Science 2024-12-23 Ryien Hosseini , Filippo Simini , Venkatram Vishwanath , Henry Hoffmann

In standard generative deep learning models, such as autoencoders or GANs, the size of the parameter set is proportional to the complexity of the generated data distribution. A significant challenge is to deploy resource-hungry deep…

Machine Learning · Computer Science 2021-10-29 Shreshth Tuli , Shikhar Tuli , Giuliano Casale , Nicholas R. Jennings

Generative Adversarial Networks (GANs) are proficient at generating synthetic data but continue to suffer from mode collapse, where the generator produces a narrow range of outputs that fool the discriminator but fail to capture the full…

Machine Learning · Computer Science 2025-11-03 Mahsa Valizadeh , Rui Tuo , James Caverlee

Existing studies on dynamic multi-objective optimization focus on problems with time-dependent objective functions, while the ones with a changing number of objectives have rarely been considered in the literature. Instead of changing the…

Neural and Evolutionary Computing · Computer Science 2017-02-20 Renzhi Chen , Ke Li , Xin Yao

Decentralized stochastic bilevel optimization (DSBO) is a powerful tool for various machine learning tasks, including decentralized meta-learning and hyperparameter tuning. Existing DSBO methods primarily address problems with strongly…

Optimization and Control · Mathematics 2026-02-02 Yaoshuai Ma , Xiao Wang , Wei Yao , Jin Zhang

Boundary representation (B-rep) of geometric models is a fundamental format in Computer-Aided Design (CAD). However, automatically generating valid and high-quality B-rep models remains challenging due to the complex interdependence between…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Jing Li , Yihang Fu , Falai Chen

Deep learning (DL) models require extensive data to achieve strong performance and generalization. Deep generative models (DGMs) offer a solution by synthesizing data. Yet current approaches for tabular data often fail to preserve feature…

Machine Learning · Computer Science 2026-05-06 Minh H. Vu , Daniel Edler , Carl Wibom , Tommy Löfstedt , Beatrice Melin , Martin Rosvall

Multi-objective optimization is key to solving many Engineering Design problems, where design parameters are optimized for several performance indicators. However, optimization results are highly dependent on how the designs are…

Machine Learning · Computer Science 2021-09-29 Wei Chen , Faez Ahmed

We propose a new approach to train the Generative Adversarial Nets (GANs) with a mixture of generators to overcome the mode collapsing problem. The main intuition is to employ multiple generators, instead of using a single one as in the…

Machine Learning · Computer Science 2017-10-31 Quan Hoang , Tu Dinh Nguyen , Trung Le , Dinh Phung

Disentangled generative models map a latent code vector to a target space, while enforcing that a subset of the learned latent codes are interpretable and associated with distinct properties of the target distribution. Recent advances have…

Machine Learning · Computer Science 2020-08-10 Zinan Lin , Kiran Koshy Thekumparampil , Giulia Fanti , Sewoong Oh

We introduce a nonmonotone extension of the Front Descent framework for multiobjective optimization. The method uses novel nonmonotone line searches that allow temporary increases in some objective functions. To our knowledge, this is the…

Optimization and Control · Mathematics 2025-09-03 Pierluigi Mansueto

Controllable scene generation could reduce the cost of diverse data collection substantially for autonomous driving. Prior works formulate the traffic layout generation as predictive progress, either by denoising entire sequences at once or…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Yunsong Zhou , Naisheng Ye , William Ljungbergh , Tianyu Li , Jiazhi Yang , Zetong Yang , Hongzi Zhu , Christoffer Petersson , Hongyang Li

This paper proposes a novel deep generative model, called BSDE-Gen, which combines the flexibility of backward stochastic differential equations (BSDEs) with the power of deep neural networks for generating high-dimensional complex target…

Machine Learning · Computer Science 2023-04-11 Xingcheng Xu

This paper introduces a differential dynamic programming (DDP) based framework for polynomial trajectory generation for differentially flat systems. In particular, instead of using a linear equation with increasing size to represent…

Optimization and Control · Mathematics 2021-09-13 Kun Cao , Muqing Cao , Shenghai Yuan , Lihua Xie

Most current computer vision datasets are composed of disconnected sets, such as images from different classes. We prove that distributions of this type of data cannot be represented with a continuous generative network without error. They…

Machine Learning · Computer Science 2020-06-26 Lorenzo Luzi , Randall Balestriero , Richard G. Baraniuk
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