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The automated detection of cortical lesions (CLs) in patients with multiple sclerosis (MS) is a challenging task that, despite its clinical relevance, has received very little attention. Accurate detection of the small and scarce lesions…

Image and Video Processing · Electrical Eng. & Systems 2020-08-18 Francesco La Rosa , Erin S Beck , Ahmed Abdulkadir , Jean-Philippe Thiran , Daniel S Reich , Pascal Sati , Meritxell Bach Cuadra

Ultra-high resolution 7 tesla (7T) magnetic resonance imaging (MRI) provides detailed anatomical views, offering better signal-to-noise ratio, resolution and tissue contrast than 3T MRI, though at the cost of accessibility. We present an…

Automated segmentation of multiple sclerosis (MS) lesions from MRI scans is important to quantify disease progression. In recent years, convolutional neural networks (CNNs) have shown top performance for this task when a large amount of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Jiacheng Wang , Hao Li , Han Liu , Dewei Hu , Daiwei Lu , Keejin Yoon , Kelsey Barter , Francesca Bagnato , Ipek Oguz

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

White matter hyperintensity (WMH) remains the top imaging biomarker for neurodegenerative diseases. Robust and accurate segmentation of WMH holds paramount significance for neuroimaging studies. The growing shift from 3T to 7T MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-02-21 Jinghang Li , Tales Santini , Yuanzhe Huang , Joseph M. Mettenburg , Tamer S. Ibrahim , Howard J. Aizenstein , Minjie Wu

Lesion segmentation in medical imaging has been an important topic in clinical research. Researchers have proposed various detection and segmentation algorithms to address this task. Recently, deep learning-based approaches have…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Dong Yang , Andriy Myronenko , Xiaosong Wang , Ziyue Xu , Holger R. Roth , Daguang Xu

Automatic multiple sclerosis (MS) lesion segmentation using multi-contrast magnetic resonance (MR) images provides improved efficiency and reproducibility compared to manual delineation. Current state-of-the-art automatic MS lesion…

Image and Video Processing · Electrical Eng. & Systems 2023-12-05 Jinwei Zhang , Lianrui Zuo , Blake E. Dewey , Samuel W. Remedios , Dzung L. Pham , Aaron Carass , Jerry L. Prince

The detection of new or enlarged white-matter lesions in multiple sclerosis is a vital task in the monitoring of patients undergoing disease-modifying treatment for multiple sclerosis. However, the definition of 'new or enlarged' is not…

Multiple sclerosis (MS) is a demyelinating disease that affects more than 2 million people worldwide. The most used imaging technique to help in its diagnosis and follow-up is magnetic resonance imaging (MRI). Fluid Attenuated Inversion…

Computer Vision and Pattern Recognition · Computer Science 2018-07-26 Paulo G. L. Freire , Ricardo J. Ferrari

A major challenge in stroke research and stroke recovery predictions is the determination of a stroke lesion's extent and its impact on relevant brain systems. Manual segmentation of stroke lesions from 3D magnetic resonance (MR) imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Sovesh Mohapatra , Advait Gosai , Anant Shinde , Aleksei Rutkovskii , Sirisha Nouduri , Gottfried Schlaug

Automated segmentation of multiple sclerosis (MS) lesions using multicontrast magnetic resonance (MR) images improves efficiency and reproducibility compared to manual delineation, with deep learning (DL) methods achieving state-of-the-art…

Ultrahigh-field (UHF) magnetic resonance imaging (MRI), i.e., 7T MRI, provides superior anatomical details of internal brain structures owing to its enhanced signal-to-noise ratio and susceptibility-induced contrast. However, the widespread…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Kwanseok Oh , Jieun Lee , Da-Woon Heo , Dinggang Shen , Heung-Il Suk

Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central nervous system, characterized by the appearance of focal lesions in the white and gray matter that topographically correlate with an individual…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Yang Ma , Chaoyi Zhang , Mariano Cabezas , Yang Song , Zihao Tang , Dongnan Liu , Weidong Cai , Michael Barnett , Chenyu Wang

Introduction: Multiple Sclerosis (MS) is a chronic disease that affects millions of people across the globe. MS can critically affect different organs of the central nervous system such as the eyes, the spinal cord, and the brain.…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Atif Shah , Maged S. Al-Shaibani , Moataz Ahmad , Reem Bunyan

Segmentation of lesions on CT enables automatic measurement for clinical assessment of chronic diseases (e.g., lymphoma). Integrating large language models (LLMs) into the lesion segmentation workflow has the potential to combine imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Ruida Cheng , Tejas Sudharshan Mathai , Pritam Mukherjee , Benjamin Hou , Qingqing Zhu , Zhiyong Lu , Matthew McAuliffe , Ronald M. Summers

In this paper, we present a novel automated method for White Matter (WM) lesion segmentation of Multiple Sclerosis (MS) patient images. Our approach is based on a cascade of two 3D patch-wise convolutional neural networks (CNN). The first…

Multiple Sclerosis (MS) is an autoimmune disease that leads to lesions in the central nervous system. Magnetic resonance (MR) images provide sufficient imaging contrast to visualize and detect lesions, particularly those in the white…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Snehashis Roy , John A. Butman , Daniel S. Reich , Peter A. Calabresi , Dzung L. Pham

Segmentation of both large and small white matter hyperintensities/lesions in brain MR images is a challenging task which has drawn much attention in recent years. We propose a multi-scale aggregation model framework to deal with…

Computer Vision and Pattern Recognition · Computer Science 2019-02-28 Hongwei Li , Jianguo Zhang , Mark Muehlau , Jan Kirschke , Bjoern Menze

Recent advances in automated skin cancer diagnosis have yielded performance on par with board-certified dermatologists. However, these approaches formulated skin cancer diagnosis as a simple classification task, dismissing the potential…

Image and Video Processing · Electrical Eng. & Systems 2021-12-06 Jingye Chen , Jieneng Chen , Zongwei Zhou , Bin Li , Alan Yuille , Yongyi Lu

Objective: Multiple Sclerosis (MS) is an autoimmune, and demyelinating disease that leads to lesions in the central nervous system. This disease can be tracked and diagnosed using Magnetic Resonance Imaging (MRI). Up to now a multitude of…

Image and Video Processing · Electrical Eng. & Systems 2022-01-07 Mehdi SadeghiBakhi , Hamidreza Pourreza , Hamidreza Mahyar
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