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The present paper examines the viability of a radically novel idea for brain-computer interface (BCI), which could lead to novel technological, experimental and clinical applications. BCIs are computer-based systems that enable either…

Neurons and Cognition · Quantitative Biology 2021-12-03 Vahid Salari , Serafim Rodrigues , Erhan Saglamyurek , Christoph Simon , Daniel Oblak

Four-dimensional ultrasound imaging of complex biological systems such as the brain is technically challenging because of the spatiotemporal sampling requirements. We present computational ultrasound imaging (cUSi), a new imaging method…

Non-invasive Brain-Computer Interfaces (BCI) offer a safe and accessible means of connecting the human brain to external devices, with broad applications in home and clinical settings to enhance human capabilities. However, the high noise…

Machine Learning · Computer Science 2025-08-06 Jiamin Wu , Zichen Ren , Junyu Wang , Pengyu Zhu , Yonghao Song , Mianxin Liu , Qihao Zheng , Lei Bai , Wanli Ouyang , Chunfeng Song

Objective. Personalized transcranial electrical stimulation (tES) has gained growing attention due to the substantial inter-individual variability in brain anatomy and physiology. While previous reviews have discussed the physiological…

Neurons and Cognition · Quantitative Biology 2025-11-06 Mo Wang , Kexin Zheng , Yingyue Xin , Xiang Chen , Yiling Liu , Huichun Luo , Jingsheng Tang , Tifei Yuan , Hongkai Wen , Pengfei Wei , Quanying Liu

Transcranial focused ultrasound stimulation (TUS) holds promise for non-invasive neural modulation in treating neurological disorders. Most clinically relevant targets are deep within the brain (near or at its geometric center), surrounded…

Brain-Computer Interfaces (BCIs) enable converting the brain electrical activity of an interface user to the user commands. BCI research studies demonstrated encouraging results in different areas such as neurorehabilitation, control of…

Signal Processing · Electrical Eng. & Systems 2021-10-07 Alexandra Samsonova , Barry J. Devereux , Georgios Karakonstantis , Lev Mukhanov

Brain-computer interfaces (BCIs) make possible to interact with the external environment by decoding the mental intention of individuals. BCIs can therefore be used to address basic neuroscience questions but also to unlock a variety of…

Neurons and Cognition · Quantitative Biology 2021-02-12 Juliana Gonzalez-Astudillo , Tiziana Cattai , Giulia Bassignana , Marie-Constance Corsi , Fabrizio De Vico Fallani

The integration of brain-computer interfaces (BCIs) into the realm of smart wheelchair (SW) technology signifies a notable leap forward in enhancing the mobility and autonomy of individuals with physical disabilities. BCIs are a technology…

Human-Computer Interaction · Computer Science 2024-04-30 Shiva Ghasemi , Denis Gracanin , Mohammad Azab

In 2013, the UltraHaptics system demonstrated that focused ultrasound could generate perceivable mid-air tactile sensations, building on earlier explorations of airborne ultrasound as a haptic medium. These contributions established…

Human-Computer Interaction · Computer Science 2025-12-09 Arthur Fleig

In the emerging research field of bioelectronic medicine, it has been indicated that neuromodulation of the Vagus Nerve (VN) has the potential to treat various conditions such as epilepsy, depression, and autoimmune diseases. In order to…

Accurate targeting is critical for the effectiveness of transcranial focused ultrasound (tFUS) neuromodulation. While CT provides accurate skull acoustic properties, its ionizing radiation and poor soft tissue contrast limit clinical…

Medical Physics · Physics 2025-07-14 Hengyu Gao , Shaodong Ding , Ziyang Liu , Jiefu Zhang , Bolun Li , Zhiwu An , Li Wang , Jing Jing , Tao Liu , Yubo Fan , Zhongtao Hu

Noninvasive brain stimulation (NIBS) encompasses transcranial stimulation techniques that can influence brain excitability. These techniques have the potential to treat conditions like depression, anxiety, and chronic pain, and to provide…

Digital Libraries · Computer Science 2023-10-11 Swathi Anil , Jennifer D'Souza

Imaging the human brain vasculature with high spatial and temporal resolution remains challenging in the clinic today. Transcranial ultrasound is scarcely used for cerebrovascular imaging, due to low sensitivity and strong phase aberrations…

Accurate neuronavigation is critical for effective transcranial magnetic stimulation (TMS), as stimulation outcomes depend directly on precise coil placement. Existing neuronavigation systems are often costly, complex, and prone to tracking…

Human-Computer Interaction · Computer Science 2026-01-26 Xuyi Hu , Ke Ma , Siwei Liu , Per Ola Kristensson , Stefan Goetz

Traditional brain-computer interfaces (BCIs), reliant on costly electroencephalography or invasive implants, struggle with complex human-computer interactions due to setup complexity and limited precision. We present NeuGaze, a novel…

Human-Computer Interaction · Computer Science 2025-04-22 Yiqian Yang

Designs for implanted brain-computer interfaces (BCIs) have increased significantly in recent years. Each device promises better clinical outcomes and quality-of-life improvements, yet due to severe and inflexible safety constraints,…

Hardware Architecture · Computer Science 2024-09-27 Muhammed Ugur , Raghavendra Pradyumna Pothukuchi , Abhishek Bhattacharjee

Transcranial ultrasound (TUS) has emerged as a promising tool in clinical and research settings due to its potential to modulate neuronal activity, open the blood-brain barrier, facilitate targeted drug delivery via nanoparticles, and…

Medical Physics · Physics 2024-10-29 Kasra Naftchi-Ardebili , Karanpartap Singh , Gerald R. Popelka , Kim Butts Pauly

Detailed exploration on Brain Computer Interface (BCI) and its recent trends has been done in this paper. Work is being done to identify objects, images, videos and their color compositions. Efforts are on the way in understanding speech,…

Human-Computer Interaction · Computer Science 2012-11-13 T. Kameswara Rao , M. Rajya Lakshmi , T. V. Prasad

Transcranial ultrasound therapy uses focused acoustic energy to induce therapeutic bioeffects in the brain. Ultrasound must be transmitted through the skull, which is highly attenuating and heterogeneous, causing beam distortion, reducing…

Low-intensity ultrasonic waves can remotely and nondestructively excite central nervous system (CNS) neurons. While diverse applications for this effect are already emerging, the biophysical transduction mechanism underlying this excitation…

Neurons and Cognition · Quantitative Biology 2014-01-29 Michael Plaksin , Shy Shoham , Eitan Kimmel