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4D-flow magnetic resonance imaging (MRI) is an emerging imaging technique where spatiotemporal 3D blood velocity can be captured with full volumetric coverage in a single non-invasive examination. This enables qualitative and quantitative…

Image and Video Processing · Electrical Eng. & Systems 2020-04-16 Edward Ferdian , Avan Suinesiaputra , David Dubowitz , Debbie Zhao , Alan Wang , Brett Cowan , Alistair Young

Background: Image reconstruction from highly undersampled 4D flow MRI data can be very time consuming and may result in significant underestimation of velocities depending on regularization, thereby limiting the applicability of the method.…

Medical Physics · Physics 2025-04-01 Luuk Jacobs , Marco Piccirelli , Valery Vishnevskiy , Sebastian Kozerke

4D Flow Magnetic Resonance Imaging (4D Flow MRI) is a non-invasive technique for volumetric, time-resolved blood flow quantification. However, apparent trade-offs between acquisition time, image noise, and resolution limit clinical…

As the original velocity field obtained from four-dimensional (4D) flow magnetic resonance imaging (MRI) contains considerable amount of noises and errors, the available Divergence-free smoothing (DFS) method can be used to process the 4D…

Computational Engineering, Finance, and Science · Computer Science 2019-12-10 Qi Gao , Xingli Liu , Hongping Wang , Fei Li , Peng Wu , Zhaozhuo Niu , Mansu Jin , RunJie Wei

Phase-contrast magnetic resonance imaging (MRI) provides time-resolved quantification of blood flow dynamics that can aid clinical diagnosis. Long in vivo scan times due to repeated three-dimensional (3D) volume sampling over cardiac phases…

Image and Video Processing · Electrical Eng. & Systems 2020-04-22 Valery Vishnevskiy , Jonas Walheim , Sebastian Kozerke

4D flow MRI is a non-invasive imaging method that can measure blood flow velocities over time. However, the velocity fields detected by this technique have limitations due to low resolution and measurement noise. Coordinate-based neural…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Simone Saitta , Marcello Carioni , Subhadip Mukherjee , Carola-Bibiane Schönlieb , Alberto Redaelli

We introduce SMURF, a scalable and unsupervised machine learning method for simultaneously segmenting vascular geometries and reconstructing velocity fields from 4D flow MRI data. SMURF models geometry and velocity fields using multilayer…

Medical Physics · Physics 2026-01-27 Atharva Hans , Abhishek Singh , Pavlos Vlachos , Ilias Bilionis

Four-dimensional (4D) Flow MRI can noninvasively measure cerebrovascular hemodynamics but remains underused clinically because current workflows rely on manual vessel segmentation and yield velocity fields sensitive to noise, artifacts, and…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Abhishek Singh , Vitaliy L. Rayz , Pavlos P. Vlachos

Super-resolution is widely used in medical imaging to enhance low-quality data, reducing scan time and improving abnormality detection. Conventional super-resolution approaches typically rely on paired datasets of downsampled and original…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Xiaoyi Wen , Fei Jiang

Deep Learning (DL) algorithms are becoming increasingly popular for the reconstruction of high-resolution turbulent flows (aka super-resolution). However, current DL approaches perform spatially uniform super-resolution - a key performance…

We propose FlowReg, a deep learning-based framework for unsupervised image registration for neuroimaging applications. The system is composed of two architectures that are trained sequentially: FlowReg-A which affinely corrects for gross…

Computer Vision and Pattern Recognition · Computer Science 2021-09-02 Sergiu Mocanu , Alan R. Moody , April Khademi

4D Flow Magnetic Resonance Imaging (4D Flow MRI) is a non-invasive measurement technique capable of quantifying blood flow across the cardiovascular system. While practical use is limited by spatial resolution and image noise, incorporation…

4D Flow MRI is the state of the art technique for measuring blood flow, and it provides valuable information for inverse problems in the cardiovascular system. However, 4D Flow MRI has a very long acquisition time, straining healthcare…

Numerical Analysis · Mathematics 2025-12-09 Miriam Löcke , Pim van Ooij , Cristóbal Bertoglio

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

Computer Vision and Pattern Recognition · Computer Science 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

Four-dimensional Flow MRI enables non-invasive, time-resolved imaging of blood flow in three spatial dimensions, offering valuable insights into complex hemodynamics. However, its clinical utility is limited by low spatial resolution and…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 Aurélien de Turenne , Rémi Cart-Lamy , Denis Kouamé

Unsupervised anomaly detection and localization is crucial to the practical application when collecting and labeling sufficient anomaly data is infeasible. Most existing representation-based approaches extract normal image features with a…

Computer Vision and Pattern Recognition · Computer Science 2021-11-17 Jiawei Yu , Ye Zheng , Xiang Wang , Wei Li , Yushuang Wu , Rui Zhao , Liwei Wu

Time-resolved three-dimensional flow MRI (4D flow MRI) provides a unique non-invasive solution to visualize and quantify hemodynamics in blood vessels such as the aortic arch. However, most current analysis methods for arterial 4D flow MRI…

Computer Vision and Pattern Recognition · Computer Science 2024-07-31 Simone Garzia , Patryk Rygiel , Sven Dummer , Filippo Cademartiri , Simona Celi , Jelmer M. Wolterink

Sparse reconstruction is an important aspect of MRI, helping to reduce acquisition time and improve spatial-temporal resolution. Popular methods are based mostly on compressed sensing (CS), which relies on the random sampling of k-space to…

Image and Video Processing · Electrical Eng. & Systems 2023-10-17 Marlon E. Bran Lorenzana , Shekhar S. Chandra , Feng Liu

To correct for respiratory motion in PET imaging, an interpretable and unsupervised deep learning technique, FlowNet-PET, was constructed. The network was trained to predict the optical flow between two PET frames from different breathing…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Teaghan O'Briain , Carlos Uribe , Kwang Moo Yi , Jonas Teuwen , Ioannis Sechopoulos , Magdalena Bazalova-Carter

Deformable medical image registration is a crucial aspect of medical image analysis. In recent years, researchers have begun leveraging auxiliary tasks (such as supervised segmentation) to provide anatomical structure information for the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Hongchao Zhou , Shunbo Hu
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