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Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

With artificial intelligence (AI) embedded in many everyday software systems, effectively and reliably developing and maintaining AI systems becomes an essential skill for software developers. However, the complexity inherent to AI poses…

Human-Computer Interaction · Computer Science 2025-04-22 Thomas Weber

Explainable AI (XAI) refers to techniques that provide human-understandable insights into the workings of AI models. Recently, the focus of XAI is being extended toward explaining Large Language Models (LLMs). This extension calls for a…

State of the art Artificial Intelligence (AI) techniques have reached an impressive complexity. Consequently, researchers are discovering more and more methods to use them in real-world applications. However, the complexity of such systems…

Artificial Intelligence · Computer Science 2021-11-08 Marco Matarese , Francesco Rea , Alessandra Sciutti

As artificial intelligence (AI) systems become increasingly complex and ubiquitous, these systems will be responsible for making decisions that directly affect individuals and society as a whole. Such decisions will need to be justified due…

Artificial Intelligence · Computer Science 2018-12-21 Prashan Madumal , Ronal Singh , Joshua Newn , Frank Vetere

Explainable Artificial Intelligence (XAI) plays a critical role in fostering user trust and understanding in AI-driven systems. However, the design of effective XAI interfaces presents significant challenges, particularly for UX…

Human-Computer Interaction · Computer Science 2025-06-23 Mohammad Naiseh , Huseyin Dogan , Stephen Giff , Nan Jiang

Artificial intelligence-driven adaptive learning systems are reshaping education through data-driven adaptation of learning experiences. Yet many of these systems lack transparency, offering limited insight into how decisions are made. Most…

Artificial Intelligence · Computer Science 2025-08-04 Maryam Mosleh , Marie Devlin , Ellis Solaiman

AI is becoming increasingly common across different domains. However, as sophisticated AI-based systems are often black-boxed, rendering the decision-making logic opaque, users find it challenging to comply with their recommendations.…

Artificial Intelligence · Computer Science 2024-06-19 Niklas Kühl , Christian Meske , Maximilian Nitsche , Jodie Lobana

Artificial Intelligence in Medicine has made significant progress with emerging applications in medical imaging, patient care, and other areas. While these applications have proven successful in retrospective studies, very few of them were…

Artificial Intelligence · Computer Science 2023-08-11 Nicoletta Prentzas , Antonis Kakas , Constantinos S. Pattichis

As the manufacturing industry advances with sensor integration and automation, the opaque nature of deep learning models in machine learning poses a significant challenge for fault detection and diagnosis. And despite the related predictive…

Artificial Intelligence · Computer Science 2024-06-11 Ahmed Maged , Salah Haridy , Herman Shen

Large Language Models (LLMs) have played a pivotal role in advancing Artificial Intelligence (AI). However, despite their achievements, LLMs often struggle to explain their decision-making processes, making them a 'black box' and presenting…

Computation and Language · Computer Science 2025-06-30 Avash Palikhe , Zhenyu Yu , Zichong Wang , Wenbin Zhang

Artificial Intelligence (AI) is rapidly expanding and integrating more into daily life to automate tasks, guide decision making, and enhance efficiency. However, complex AI models, which make decisions without providing clear explanations…

Software Engineering · Computer Science 2025-09-03 Lakshit Arora , Sanjay Surendranath Girija , Shashank Kapoor , Aman Raj , Dipen Pradhan , Ankit Shetgaonkar

The unprecedented performance of machine learning models in recent years, particularly Deep Learning and transformer models, has resulted in their application in various domains such as finance, healthcare, and education. However, the…

Human-Computer Interaction · Computer Science 2023-12-20 Milad Rogha

Artificial intelligence (AI) enables machines to learn from human experience, adjust to new inputs, and perform human-like tasks. AI is progressing rapidly and is transforming the way businesses operate, from process automation to cognitive…

Machine Learning · Computer Science 2021-12-17 Ambreen Hanif

Artificial intelligence (AI) has rapidly developed through advancements in computational power and the growth of massive datasets. However, this progress has also heightened challenges in interpreting the "black-box" nature of AI models. To…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Shilin Sun , Wenbin An , Feng Tian , Fang Nan , Qidong Liu , Jun Liu , Nazaraf Shah , Ping Chen

Explainable Artificial Intelligence (XAI) addresses the growing need for transparency and interpretability in AI systems, enabling trust and accountability in decision-making processes. This book offers a comprehensive guide to XAI,…

Explainable artificial intelligence (XAI) has become increasingly important in biomedical image analysis to promote transparency, trust, and clinical adoption of DL models. While several surveys have reviewed XAI techniques, they often lack…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Getamesay Haile Dagnaw , Yanming Zhu , Muhammad Hassan Maqsood , Wencheng Yang , Xingshuai Dong , Xuefei Yin , Alan Wee-Chung Liew

In the last years, Artificial Intelligence (AI) has achieved a notable momentum that may deliver the best of expectations over many application sectors across the field. For this to occur, the entire community stands in front of the barrier…

Explainable Artificial Intelligence (XAI) has become popular in the last few years. The Artificial Intelligence (AI) community in general, and the Machine Learning (ML) community in particular, is coming to the realisation that in many…

Artificial Intelligence · Computer Science 2026-02-24 Raymond Sheh , Isaac Monteath

The increasing use of Machine Learning (ML) in sensitive domains such as healthcare, finance, and public policy has raised concerns about the transparency of automated decisions. Explainable AI (XAI) addresses this by clarifying how models…

Artificial Intelligence · Computer Science 2026-02-13 Natalia Abarca , Andrés Carvallo , Claudia López Moncada , Felipe Bravo-Marquez