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Large Language Models (LLMs) have revolutionized natural language processing through their state of art reasoning capabilities. This paper explores the convergence of LLM reasoning techniques and feature generation for machine learning…

Computation and Language · Computer Science 2025-03-21 Dharani Chandra

The classification of genetic variants, particularly Variants of Uncertain Significance (VUS), poses a significant challenge in clinical genetics and precision medicine. Large Language Models (LLMs) have emerged as transformative tools in…

Motivation: Patient-generated text contains critical information about patients' lived experiences, social circumstances, and engagement in care, including factors that strongly influence adherence, care coordination, and health equity.…

Computation and Language · Computer Science 2026-03-09 Samah Fodeh , Linhai Ma , Ganesh Puthiaraju , Srivani Talakokkul , Afshan Khan , Ashley Hagaman , Sarah Lowe , Aimee Roundtree

The increasing adoption of large language models (LLMs) has raised serious concerns about their reliability and trustworthiness. As a result, a growing body of research focuses on evidence-based text generation with LLMs, aiming to link…

Computation and Language · Computer Science 2026-04-17 Tobias Schreieder , Tim Schopf , Michael Färber

Connectomics - the mapping of neural connections in an organism's brain - currently requires extraordinary human effort to proofread the data collected from imaging and machine-learning assisted segmentation. With the growing excitement…

Neurons and Cognition · Quantitative Biology 2025-11-11 Jeff Brown , Andrew Kirjner , Annika Vivekananthan , Ed Boyden

Large Language Models (LLMs) are increasingly used for clinical decision support, where hallucinations and unsafe suggestions may pose direct risks to patient safety. These risks are hard to assess: subtle clinical errors are often missed…

Computation and Language · Computer Science 2026-05-14 Yinzhu Chen , Abdine Maiga , Hossein A. Rahmani , Emine Yilmaz

Recovering the structure of causal graphical models from observational data is an essential yet challenging task for causal discovery in scientific scenarios. Domain-specific causal discovery usually relies on expert validation or prior…

Artificial Intelligence · Computer Science 2025-08-27 Taiyu Ban , Lyuzhou Chen , Derui Lyu , Xiangyu Wang , Qinrui Zhu , Qiang Tu , Huanhuan Chen

Matching cancer patients to clinical trials is essential for advancing treatment and patient care. However, the inconsistent format of medical free text documents and complex trial eligibility criteria make this process extremely…

LLMs are increasingly explored for malware analysis; however, current LLM-based malware attribution remains limited by unsupported indicators and insufficient code-level grounding for identifying malicious and vulnerable code segments. To…

Cryptography and Security · Computer Science 2026-05-08 Christopher G. Pedraza Pohlenz , Hassan Jalil Hadi , Ali Hassan , Ali Shoker

Objective: Function is increasingly recognized as an important indicator of whole-person health. This study evaluates the ability of publicly available large language models (LLMs) to accurately identify the presence of functioning…

Computation and Language · Computer Science 2023-12-19 Tuan Dung Le , Thanh Duong , Thanh Thieu

Qualitative analysis of textual contents unpacks rich and valuable information by assigning labels to the data. However, this process is often labor-intensive, particularly when working with large datasets. While recent AI-based tools…

Computation and Language · Computer Science 2023-04-24 Ziang Xiao , Xingdi Yuan , Q. Vera Liao , Rania Abdelghani , Pierre-Yves Oudeyer

Tracking how data is mentioned and used in research papers provides critical insights for improving data discoverability, quality, and production. However, manually identifying and classifying dataset mentions across vast academic…

Computation and Language · Computer Science 2025-02-17 Aivin V. Solatorio , Rafael Macalaba , James Liounis

Interpretation is critical for disease diagnosis, but existing models struggle to balance predictive accuracy with human-understandable rationales. While large language models (LLMs) offer strong reasoning abilities, their clinical use is…

Computation and Language · Computer Science 2025-07-15 Shuai Niu , Jing Ma , Hongzhan Lin , Liang Bai , Zhihua Wang , Yida Xu , Yunya Song , Xian Yang

With their growing capabilities, generative large language models (LLMs) are being increasingly investigated for complex medical tasks. However, their effectiveness in real-world clinical applications remains underexplored. To address this,…

Computation and Language · Computer Science 2026-01-27 Paul Grundmann , Dennis Fast , Jan Frick , Thomas Steffek , Felix Gers , Wolfgang Nejdl , Alexander Löser

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

Accurate symptom-to-disease classification and clinically grounded treatment recommendations remain challenging, particularly in heterogeneous patient settings with high diagnostic risk. Existing large language model (LLM)-based systems…

While large language models (LLMs) bring not only performance but also complexity, recent work has started to turn LLMs into data generators rather than task inferencers, where another affordable task model is trained for efficient…

Computation and Language · Computer Science 2023-05-24 Jiacheng Ye , Chengzu Li , Lingpeng Kong , Tao Yu

Despite the dramatic progress in Large Language Model (LLM) development, LLMs often provide seemingly plausible but not factual information, often referred to as hallucinations. Retrieval-augmented LLMs provide a non-parametric approach to…

Computation and Language · Computer Science 2023-11-09 Sai Munikoti , Anurag Acharya , Sridevi Wagle , Sameera Horawalavithana

Large language models (LLMs) hold transformative potential for medical decision support yet their application in psychiatry remains constrained by hallucinations and superficial reasoning. This limitation is particularly acute in…

Long text classification is challenging for Large Language Models (LLMs) due to token limits and high computational costs. This study explores whether a Retrieval Augmented Generation (RAG) approach using only the most relevant text…