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Causal decomposition analyses can help build the evidence base for interventions that address health disparities (inequities). They ask how disparities in outcomes may change under hypothetical intervention. Through study design and…

Methodology · Statistics 2020-09-17 John W. Jackson

Observational studies are needed when experiments are not possible. Within study comparisons (WSC) compare observational and experimental estimates that test the same hypothesis using the same treatment group, outcome, and estimand.…

Detecting out-of-distribution (OOD) data is critical for machine learning, be it for safety reasons or to enable open-ended learning. However, beyond mere detection, choosing an appropriate course of action typically hinges on the type of…

Machine Learning · Computer Science 2026-04-28 Achref Jaziri , Martin Rogmann , Martin Mundt , Visvanathan Ramesh

Machine learning models perform well on several healthcare tasks and can help reduce the burden on the healthcare system. However, the lack of explainability is a major roadblock to their adoption in hospitals. \textit{How can the decision…

Machine Learning · Computer Science 2023-06-13 Supriya Nagesh , Nina Mishra , Yonatan Naamad , James M. Rehg , Mehul A. Shah , Alexei Wagner

Detecting and rejecting unknown out-of-distribution (OOD) samples is critical for deployed neural networks to void unreliable predictions. In real-world scenarios, however, the efficacy of existing OOD detection methods is often impeded by…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Kai Liu , Zhihang Fu , Sheng Jin , Chao Chen , Ze Chen , Rongxin Jiang , Fan Zhou , Yaowu Chen , Jieping Ye

Deep Learning models are easily disturbed by variations in the input images that were not seen during training, resulting in unpredictable behaviours. Such Out-of-Distribution (OOD) images represent a significant challenge in the context of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Benjamin Lambert , Florence Forbes , Senan Doyle , Alan Tucholka , Michel Dojat

Discriminative neural networks offer little or no performance guarantees when deployed on data not generated by the same process as the training distribution. On such out-of-distribution (OOD) inputs, the prediction may not only be…

A key objective of decomposition analysis is to identify a factor (the 'mediator') contributing to disparities in an outcome between social groups. In decomposition analysis, a scholarly interest often centers on estimating how much the…

Methodology · Statistics 2022-05-27 Soojin Park , Suyeon Kang , Chioun Lee , Shujie Ma

Accurate and explainable out-of-distribution (OOD) detection is required to use machine learning systems safely. Previous work has shown that feature distance to decision boundaries can be used to identify OOD data effectively. In this…

Machine Learning · Computer Science 2025-08-15 Maria Stoica , Francesco Leofante , Alessio Lomuscio

Studies that collect multi-outcome data such as tobacco and alcohol use are becoming increasingly common. In principle, multi-outcomes studies investigate the correlations between outcomes, including, causal links and/or joint…

Methodology · Statistics 2022-11-03 George G. Vega Yon , Mary Jo Pugh , Thomas W. Valente

Medical journals have adhered to a reporting practice that seriously limits the usefulness of published trial findings. Medical decision makers commonly observe many patient covariates and seek to use this information to personalize…

Econometrics · Economics 2022-09-07 Sheyu Li , Valentyn Litvin , Charles F. Manski

Machine learning models have achieved high overall accuracy in medical image analysis. However, performance disparities on specific patient groups pose challenges to their clinical utility, safety, and fairness. This can affect known…

Machine Learning · Computer Science 2024-10-23 Vincent Olesen , Nina Weng , Aasa Feragen , Eike Petersen

Confounding variables are a well known source of nuisance in biomedical studies. They present an even greater challenge when we combine them with black-box machine learning techniques that operate on raw data. This work presents two case…

In the causal adjustment setting, variable selection techniques based on one of either the outcome or treatment allocation model can result in the omission of confounders, which leads to bias, or the inclusion of spurious variables, which…

Methodology · Statistics 2015-11-30 Ashkan Ertefaie , Masoud Asgharian , David Stephens

Covariate balancing is a popular technique for controlling confounding in observational studies. It finds weights for the treatment group which are close to uniform, but make the group's covariate means (approximately) equal to those of the…

Methodology · Statistics 2025-03-07 Shiva Kaul , Min-Gyu Kim

Observational studies are rising in importance due to the widespread accumulation of data in fields such as healthcare, education, employment and ecology. We consider the task of answering counterfactual questions such as, "Would this…

Machine Learning · Statistics 2018-06-07 Fredrik D. Johansson , Uri Shalit , David Sontag

Observational studies are frequently used to estimate the effect of an exposure or treatment on an outcome. To obtain an unbiased estimate of the treatment effect, it is crucial to measure the exposure accurately. A common type of exposure…

Methodology · Statistics 2024-07-02 Suhwan Bong , Kwonsang Lee , Francesca Dominici

In many science and industry settings, a central challenge is designing experiments under time and budget constraints. Bayesian Optimal Experimental Design (BOED) is a paradigm to pick maximally informative designs that has been widely…

Machine Learning · Statistics 2026-04-02 Roubing Tang , Sabina J. Sloman , Samuel Kaski

Healthcare data often come from multiple sites in which the correlations between confounding variables can vary widely. If deep learning models exploit these unstable correlations, they might fail catastrophically in unseen sites. Although…

Machine Learning · Computer Science 2023-10-25 Minh Nguyen , Alan Q. Wang , Heejong Kim , Mert R. Sabuncu

A majority of recent work in AI assesses models' generalization capabilities through the lens of performance on out-of-distribution (OOD) datasets. Despite their practicality, such evaluations build upon a strong assumption: that OOD…

Computation and Language · Computer Science 2025-08-27 Michal Štefánik , Timothee Mickus , Marek Kadlčík , Michal Spiegel , Josef Kuchař