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Estimating a causal effect from observational data can be biased if we do not control for self-selection. This selection is based on confounding variables that affect the treatment assignment and the outcome. Propensity score methods aim to…

Econometrics · Economics 2021-09-10 Daniel Jacob

Machine learning methods must be trusted to make appropriate decisions in real-world environments, even when faced with out-of-distribution (OOD) samples. Many current approaches simply aim to detect OOD examples and alert the user when an…

Machine Learning · Computer Science 2022-09-13 Randolph Linderman , Jingyang Zhang , Nathan Inkawhich , Hai Li , Yiran Chen

Major depressive disorder (MDD) is a heterogeneous condition; multiple underlying neurobiological substrates could be associated with treatment response variability. Understanding the sources of this variability and predicting outcomes has…

Most session-based recommender systems (SBRSs) focus on extracting information from the observed items in the current session of a user to predict a next item, ignoring the causes outside the session (called outer-session causes, OSCs) that…

Information Retrieval · Computer Science 2023-05-09 Wenzhuo Song , Shoujin Wang , Yan Wang , Kunpeng Liu , Xueyan Liu , Minghao Yin

Out-of-distribution (OOD) detection aims to identify test examples that do not belong to the training distribution and are thus unlikely to be predicted reliably. Despite a plethora of existing works, most of them focused only on the…

Machine Learning · Computer Science 2023-11-07 Reza Averly , Wei-Lun Chao

This paper develops new tools to quantify uncertainty in optimal decision making and to gain insight into which variables one should collect information about given the potential cost of measuring a large number of variables. We investigate…

Methodology · Statistics 2021-05-11 Yunan Wu , Lan Wang , Haoda Fu

Individuals often make different decisions when faced with the same context, due to personal preferences and background. For instance, judges may vary in their leniency towards certain drug-related offenses, and doctors may vary in their…

Machine Learning · Computer Science 2021-10-28 Justin Lim , Christina X Ji , Michael Oberst , Saul Blecker , Leora Horwitz , David Sontag

Out-of-distribution (OOD) generalization remains a fundamental challenge in real-world classification, where test distributions often differ substantially from training data. Most existing approaches pursue domain-invariant representations,…

Machine Learning · Computer Science 2026-01-30 Chen Cheng , Ang Li

In observational causal inference, domain knowledge often leaves multiple covariate adjustments plausible, yet which sets satisfy ignorability is untestable. Different adjustment sets can yield conflicting estimates of the average treatment…

Methodology · Statistics 2026-03-23 Aditya Ghosh , Dominik Rothenhäusler

We analyse an issue when comparing survival curves between two subgroups. We show that there is a direct relationship between estimates of subgroups' survival at a time point and positive and negative predictive values in the binary…

Methodology · Statistics 2021-05-17 Damjan Krstajic

The dearth of prescribing guidelines for physicians is one key driver of the current opioid epidemic in the United States. In this work, we analyze medical and pharmaceutical claims data to draw insights on characteristics of patients who…

Machine Learning · Computer Science 2020-05-01 Chirag Nagpal , Dennis Wei , Bhanukiran Vinzamuri , Monica Shekhar , Sara E. Berger , Subhro Das , Kush R. Varshney

Difference-in-differences (diff-in-diff) is a study design that compares outcomes of two groups (treated and comparison) at two time points (pre- and post-treatment) and is widely used in evaluating new policy implementations. For instance,…

Applications · Statistics 2019-11-28 Bret Zeldow , Laura A. Hatfield

Overlap between treatment groups is required for non-parametric estimation of causal effects. If a subgroup of subjects always receives the same intervention, we cannot estimate the effect of intervention changes on that subgroup without…

Machine Learning · Computer Science 2021-03-04 Michael Oberst , Fredrik D. Johansson , Dennis Wei , Tian Gao , Gabriel Brat , David Sontag , Kush R. Varshney

Applied analysts often use the differences-in-differences (DID) method to estimate the causal effect of policy interventions with observational data. The method is widely used, as the required before and after comparison of a treated and…

Applications · Statistics 2019-02-04 Luke J. Keele , Dylan S. Small , Jesse Y. Hsu , Colin B. Fogarty

Causal inference in longitudinal biomedical data remains a central challenge, especially in psychiatry, where symptom heterogeneity and latent confounding frequently undermine classical estimators. Most existing methods for treatment effect…

Machine Learning · Computer Science 2025-07-28 Eric V. Strobl

Distribution shifts introduce uncertainty that undermines the robustness and generalization capabilities of machine learning models. While conventional wisdom suggests that learning causal-invariant representations enhances robustness to…

Machine Learning · Computer Science 2025-05-28 Abbavaram Gowtham Reddy , Celia Rubio-Madrigal , Rebekka Burkholz , Krikamol Muandet

In the context of knowledge compilation (KC), we study the effect of augmenting Ordered Binary Decision Diagrams (OBDD) with two kinds of decomposition nodes, i.e., AND-vertices and OR-vertices which denote conjunctive and disjunctive…

Artificial Intelligence · Computer Science 2014-10-28 Yong Lai , Dayou Liu

Clinical decisions to treat and diagnose patients are affected by implicit biases formed by racism, ableism, sexism, and other stereotypes. These biases reflect broader systemic discrimination in healthcare and risk marginalizing already…

Machine Learning · Computer Science 2025-01-29 Kara Liu , Russ Altman , Vasilis Syrgkanis

A popular method for estimating a causal treatment effect with observational data is the difference-in-differences (DiD) model. In this work, we consider an extension of the classical DiD setting to the hierarchical context in which data…

Methodology · Statistics 2019-10-17 James Normington , Eric F. Lock , Thomas A. Murray , Caroline S. Carlin

Differences-in-differences (DiD) is a causal inference method for observational longitudinal data that assumes parallel expected potential outcome trajectories between treatment groups under the counterfactual scenario where all units…

Methodology · Statistics 2026-05-12 Michael Jetsupphasuk , Didong Li , Michael G. Hudgens