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We develop a unified framework for automatic debiased machine learning (autoDML) for inference on a broad class of statistical parameters. The framework applies to any smooth functional of a nonparametric M-estimand, defined as the…

Methodology · Statistics 2026-03-23 Lars van der Laan , Aurelien Bibaut , Nathan Kallus , Alex Luedtke

Debiased inference for high-dimensional regression models has received substantial recent attention to ensure regularized estimators have valid inference. All existing methods focus on achieving Neyman orthogonality through explicitly…

Methodology · Statistics 2025-12-16 Yi Wang , Yuhao Deng , Yu Gu , Yuanjia Wang , Donglin Zeng

We develop a novel and general framework for reduced-bias $M$-estimation from asymptotically unbiased estimating functions. The framework relies on an empirical approximation of the bias by a function of derivatives of estimating function…

Methodology · Statistics 2023-08-11 Ioannis Kosmidis , Nicola Lunardon

This paper proposes a desparsified GMM estimator for estimating high-dimensional regression models allowing for, but not requiring, many more endogenous regressors than observations. We provide finite sample upper bounds on the estimation…

Statistics Theory · Mathematics 2019-09-11 Mehmet Caner , Anders Bredahl Kock

In various statistical settings, the goal is to estimate a function which is restricted by the statistical model only through a conditional moment restriction. Prominent examples include the nonparametric instrumental variable framework for…

Methodology · Statistics 2025-05-28 AmirEmad Ghassami , James M. Robins , Andrea Rotnitzky

Location estimation is a central problem in functional data analysis. In this paper, we investigate penalized spline estimators of location for discretely sampled functional data under a broad class of convex loss functions. Our framework…

Methodology · Statistics 2025-08-19 Ioannis Kalogridis

We provide adaptive inference methods, based on $\ell_1$ regularization, for regular (semi-parametric) and non-regular (nonparametric) linear functionals of the conditional expectation function. Examples of regular functionals include…

Machine Learning · Statistics 2022-10-25 Victor Chernozhukov , Whitney Newey , Rahul Singh

We develop a practical way of addressing the Errors-In-Variables (EIV) problem in the Generalized Method of Moments (GMM) framework. We focus on the settings in which the variability of the EIV is a fraction of that of the mismeasured…

Econometrics · Economics 2025-11-11 Kirill S. Evdokimov , Andrei Zeleneev

This study introduces a debiasing method for regression estimators, including high-dimensional and nonparametric regression estimators. For example, nonparametric regression methods allow for the estimation of regression functions in a…

Machine Learning · Statistics 2024-11-27 Masahiro Kato

Debiased machine learning is a meta algorithm based on bias correction and sample splitting to calculate confidence intervals for functionals, i.e. scalar summaries, of machine learning algorithms. For example, an analyst may desire the…

Machine Learning · Statistics 2022-10-25 Victor Chernozhukov , Whitney K. Newey , Rahul Singh

We propose employing a high-dimensional generalized method of moments (GMM) estimator, regularized for dimension reduction and subsequently debiased to correct for shrinkage bias (referred to as a debiased-regularized estimator), for…

Econometrics · Economics 2025-07-03 Victor Chernozhukov , Chen Huang , Weining Wang

Machine-learning (ML) methods now routinely generate regressors used in subsequent econometric analyses, for example, estimated propensity scores, control-function residuals, imputed covariates, learned proxies, or low-dimensional…

Econometrics · Economics 2026-03-17 Juan Carlos Escanciano , Telmo Pérez-Izquierdo

Standard random-effects meta-analysis relies heavily on the assumption that the underlying true effects are normally distributed. In the social sciences, where evidence synthesis increasingly involves large, highly heterogeneous datasets,…

Methodology · Statistics 2026-05-01 Daihe Sui , Elizabeth Tipton

We consider efficient estimation of flexible transformation models with interval-censored data. To reduce the dimension of semi-parametric models, the unknown monotone transformation function is approximated via monotone splines. A…

Methodology · Statistics 2019-12-30 Minggen Lu , Yan Liu , Chin-Shang Li , Jianguo Sun

New upper bounds are developed for the $L_2$ distance between $\xi/\text{Var}[\xi]^{1/2}$ and linear and quadratic functions of $z\sim N(0,I_n)$ for random variables of the form $\xi=bz^\top f(z) - \text{div} f(z)$. The linear approximation…

Statistics Theory · Mathematics 2021-09-30 Pierre C Bellec , Cun-Hui Zhang

Graphical model has been widely used to investigate the complex dependence structure of high-dimensional data, and it is common to assume that observed data follow a homogeneous graphical model. However, observations usually come from…

Methodology · Statistics 2016-01-01 Kevin Lee , Lingzhou Xue

Completely randomized experiment is the gold standard for causal inference. When the covariate information for each experimental candidate is available, one typical way is to include them in covariate adjustments for more accurate treatment…

Methodology · Statistics 2025-06-10 Xin Lu , Fan Yang , Yuhao Wang

We consider the problem of estimating the value l({\phi}) of a linear functional, where the structural function {\phi} models a nonparametric relationship in presence of instrumental variables. We propose a plug-in estimator which is based…

Statistics Theory · Mathematics 2011-09-06 Christoph Breunig , Jan Johannes

Weak identification arises in many statistical problems when key variables exhibit weak correlations-for example, when instrumental variables correlate weakly with treatment, or when proxy variables correlate weakly with unmeasured…

Statistics Theory · Mathematics 2025-11-12 Rui Wang , Kwun Chuen Gary Chan , Ting Ye

We consider debiased inference on finite-dimensional functionals of infinite-dimensional least-squares solutions to inverse problems as a way to avoid having to assume exact solutions exist. Such assumptions are substantive and not…

Machine Learning · Statistics 2026-05-27 Zikai Shen , Nathan Kallus , Dimitri Meunier , Houssam Zenati , Arthur Gretton , Aurélien Bibaut
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