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Related papers: An Interactive LLM-Based Simulator for Dementia-Re…

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This study explores a novel approach to advancing dementia care by integrating socially assistive robotics, reinforcement learning (RL), large language models (LLMs), and clinical domain expertise within a simulated environment. This…

Artificial Intelligence · Computer Science 2025-01-30 Fengpei Yuan , Nehal Hasnaeen , Ran Zhang , Bryce Bible , Joseph Riley Taylor , Hairong Qi , Fenghui Yao , Xiaopeng Zhao

Simulating dementia patients with large language models (LLMs) is challenging due to the need to jointly model cognitive impairment, emotional dynamics, and nonverbal behaviors over long conversations. We present DemMA, an expert-guided…

Multiagent Systems · Computer Science 2026-01-13 Yutong Song , Jiang Wu , Kazi Sharif , Honghui Xu , Nikil Dutt , Amir Rahmani

Alzheimer's disease is a neurodegenerative disorder marked by progressive declines in memory and language that reduce independence in daily life, motivating socially assistive robotic support. This paper presents MEMOR-E, a mobile quadruped…

Artificial Intelligence · Computer Science 2026-05-26 Maissa Abir Smaili , Eren Sadikoglu , Ransalu Senanayake

United States healthcare systems are struggling to meet the growing demand for neurological care, particularly in Alzheimer's disease and related dementias (ADRD). Generative AI built on language models (LLMs) now enables agentic AI systems…

In healthcare, the ability to care for oneself is reflected in the "Activities of Daily Living (ADL)," which serve as a measure of functional ability (functioning). A lack of functioning may lead to poor living conditions requiring personal…

Computation and Language · Computer Science 2023-07-18 Zhecheng Sheng , Raymond Finzel , Michael Lucke , Sheena Dufresne , Maria Gini , Serguei Pakhomov

Developing artificial intelligence based assistive systems to aid Persons with Dementia (PwD) requires large amounts of training data. However, data collection poses ethical, legal, economic, and logistic issues. Synthetic data generation…

Artificial Intelligence · Computer Science 2021-07-13 Muhammad Salman Shaukat , Bjarne Christian Hiller , Sebastian Bader , Thomas Kirste

Agitation is one of the neuropsychiatric symptoms with high prevalence in dementia which can negatively impact the Activities of Daily Living (ADL) and the independence of individuals. Detecting agitation episodes can assist in providing…

People with Alzheimer's disease and related dementias (ADRD) often show the problem of repetitive questioning, which brings a great burden on persons with ADRD (PwDs) and their caregivers. Conversational robots hold promise of coping with…

Robotics · Computer Science 2021-04-20 Fengpei Yuan , Amir Sadovnik , Ran Zhang , Devin Casenhiser , Eun Jin Paek , Si On Yoon , Xiaopeng Zhao

LLMs promise to overcome limitations of rule-based mental health chatbots through improved natural language capabilities, yet their ability to deliver evidence-based psychological interventions remains largely unverified because evaluations…

Human-Computer Interaction · Computer Science 2025-12-22 Florian Onur Kuhlmeier , Leon Hanschmann , Melina Rabe , Stefan Luettke , Eva-Lotta Brakemeier , Alexander Maedche

Individuals with Alzheimer's disease (AD) and Alzheimer's disease-related dementia (ADRD) experience memory and thinking changes that impact their ability to use digital daily management tools. For example, adding an event to a digital…

Artificial Intelligence · Computer Science 2026-05-12 Preyash Yadav , Michelle Cohn , Priyanka Koppolu , Hritvik Agarwal , Amey Gohil , Tejas Patil , Sasha Pimento , Alyssa Weakley

Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease. Early and precise diagnosis of AD is crucial for timely intervention and treatment planning to alleviate the progressive neurodegeneration. However, most…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Wenlong Hou , Guangqian Yang , Ye Du , Yeung Lau , Lihao Liu , Junjun He , Ling Long , Shujun Wang

Objective Alzheimer disease (AD) is the most common cause of dementia, a syndrome characterized by cognitive impairment severe enough to interfere with activities of daily life. We aimed to conduct a systematic literature review (SLR) of…

Quantitative Methods · Quantitative Biology 2021-08-31 Sayantan Kumar , Inez Oh , Suzanne Schindler , Albert M Lai , Philip R O Payne , Aditi Gupta

Family caregivers of individuals with Alzheimer's Disease and Related Dementia (AD/ADRD) face significant emotional and logistical challenges that place them at heightened risk for stress, anxiety, and depression. Although recent advances…

Human-Computer Interaction · Computer Science 2026-03-23 Jiayue Melissa Shi , Dong Whi Yoo , Keran Wang , Violeta J. Rodriguez , Ravi Karkar , Koustuv Saha

Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

Computation and Language · Computer Science 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

Early diagnosis of Alzheimer's disease and related dementias (ADRD) is critical for timely intervention, yet most diagnoses are delayed until advanced stages. While comprehensive patient narratives are essential for accurate diagnosis,…

Human-Computer Interaction · Computer Science 2026-01-28 Andrew G. Breithaupt , Nayoung Choi , James D. Finch , Jeanne M. Powell , Arin L. Nelson , Oz A. Alon , Howard J. Rosen , Jinho D. Choi

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that leads to dementia, and early intervention can greatly benefit from analyzing linguistic abnormalities. In this work, we explore the potential of Large Language Models…

Computation and Language · Computer Science 2025-12-23 Chuyuan Li , Raymond Li , Thalia S. Field , Giuseppe Carenini

Language models are increasingly being deployed for conversational support in informal caregiving contexts, where interactions often extend beyond information-seeking: caregivers seek emotional reassurance, guidance, and help, while…

One of the distinct features of this century has been the population of older adults which has been on a constant rise. Elderly people have several needs and requirements due to physical disabilities, cognitive issues, weakened memory and…

Human-Computer Interaction · Computer Science 2021-06-24 Nirmalya Thakur , Chia Y. Han

Reminiscence therapy is an inexpensive non-pharmacological therapy commonly used due to its therapeutic value for PwD, as it can be used to promote independence, positive moods and behavior, and improve their quality of life. Caregivers are…

Human-Computer Interaction · Computer Science 2022-01-10 Soraia M. Alarcão , André Santana , Carolina Maruta , Manuel J. Fonseca

Based on official estimates, 50 million people worldwide are affected by dementia, and this number increases by 10 million new patients every year. Without a cure, clinical prognostication and early intervention represent the most effective…

Computation and Language · Computer Science 2024-09-06 Francisco de Arriba-Pérez , Silvia García-Méndez
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