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Motivation: Gene set testing is typically performed in a supervised context to quantify the association between groups of genes and a clinical phenotype. In many cases, however, a gene set-based interpretation of genomic data is desired in…

Quantitative Methods · Quantitative Biology 2015-03-17 H. Robert Frost , Zhigang Li , Jason H. Moore

Normal and anomalous diffusion are ubiquitous in many complex systems [1] . Here, we define a time and space generalized diffusion equation (GDE), which uses fractional-time derivatives and transformed d-path Laplacian operators on…

Physics and Society · Physics 2022-02-02 Fernando Diaz-Diaz , Ernesto Estrada

Two-dimensional terahertz spectroscopy (2DTS) is a low-frequency analogue of two-dimensional optical spectroscopy that is rapidly maturing as a probe of a wide variety of condensed matter systems. However, a persistent problem of 2DTS is…

In this paper, we study the problem of learning multi-dimensional Gaussian Mixture Models (GMMs), with a specific focus on model order selection and efficient mixing distribution estimation. We first establish an information-theoretic lower…

Machine Learning · Statistics 2026-03-23 Xinyu Liu , Hai Zhang

In the realm of quantum-effect devices and materials, two-dimensional electron gases (2DEGs) stand as fundamental structures that promise transformative technologies. However, the presence of impurities and defects in 2DEGs poses…

Mesoscale and Nanoscale Physics · Physics 2023-10-12 Carlo da Cunha , Nobuyuki Aoki , David Ferry , Kevin Vora , Yu Zhang

Feature selection of high-dimensional labeled data with limited observations is critical for making powerful predictive modeling accessible, scalable, and interpretable for domain experts. Spectroscopy data, which records the interaction…

Machine Learning · Computer Science 2022-02-10 Frantishek Akulich , Hadis Anahideh , Manaf Sheyyab , Dhananjay Ambre

Recently, electromagnetic surrogate solvers, trained on solutions of Maxwell's equations under specific simulation conditions, enabled fast inference of computationally expensive simulations. However, conventional electromagnetic surrogate…

Machine Learning · Computer Science 2025-06-18 Joonhyuk Seo , Chanik Kang , Dongjin Seo , Haejun Chung

A valuable step in the modeling of multiscale dynamical systems in fields such as computational chemistry, biology, materials science and more, is the representative sampling of the phase space over long timescales of interest; this task is…

Machine Learning · Computer Science 2023-12-29 Ellis R. Crabtree , Juan M. Bello-Rivas , Ioannis G. Kevrekidis

3D Gaussian Splatting (3DGS) has emerged as a dominant novel-view synthesis technique, but its high memory consumption severely limits its applicability on edge devices. A growing number of 3DGS compression methods have been proposed to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-02 Jiarui Chen , Yikeng Chen , Yingshuang Zou , Ye Huang , Peng Wang , Yuan Liu , Yujing Sun , Wenping Wang

Imaging spectrometers measure electromagnetic energy scattered in their instantaneous field view in hundreds or thousands of spectral channels with higher spectral resolution than multispectral cameras. Imaging spectrometers are therefore…

Data Analysis, Statistics and Probability · Physics 2012-04-25 José M. Bioucas-Dias , Antonio Plaza , Nicolas Dobigeon , Mario Parente , Qian Du , Paul Gader , Jocelyn Chanussot

The sparsity-restricted maximum likelihood estimator (SMLE) has received considerable attention for feature screening in ultrahigh-dimensional regression. SMLE is a computationally convenient method that naturally incorporates the joint…

Other Statistics · Statistics 2022-01-11 Qianxiang Zang , Chen Xu , Kelly Burkett

Multitemporal spectral unmixing (SU) is a powerful tool to process hyperspectral image (HI) sequences due to its ability to reveal the evolution of materials over time and space in a scene. However, significant spectral variability is often…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Ricardo Augusto Borsoi , Tales Imbiriba , José Carlos Moreira Bermudez , Cédric Richard

Deep learning has emerged as the preferred modeling approach for automatic ECG analysis. In this study, we investigate three elements aimed at improving the quantitative accuracy of such systems. These components consistently enhance…

Signal Processing · Electrical Eng. & Systems 2023-08-30 Temesgen Mehari , Nils Strodthoff

This paper presents a novel extended dynamic programming approach for energy minimization (EDP) to solve the correspondence problem for stereo and motion. A significant speedup is achieved using a recursive minimum search strategy (RMS).…

Computer Vision and Pattern Recognition · Computer Science 2014-10-30 Mikhail G. Mozerov

Spectral methods have emerged as a simple yet surprisingly effective approach for extracting information from massive, noisy and incomplete data. In a nutshell, spectral methods refer to a collection of algorithms built upon the eigenvalues…

Machine Learning · Statistics 2021-10-26 Yuxin Chen , Yuejie Chi , Jianqing Fan , Cong Ma

While ordinary differential equations (ODEs) form the conceptual framework for modelling many cellular processes, specific situations demand stochastic models to capture the influence of noise. The most common formulation of stochastic…

Subcellular Processes · Quantitative Biology 2009-04-02 Mukhtar Ullah , Olaf Wolkenhauer

We consider the problem of parameter estimation in a high-dimensional generalized linear model. Spectral methods obtained via the principal eigenvector of a suitable data-dependent matrix provide a simple yet surprisingly effective…

Statistics Theory · Mathematics 2025-07-11 Yihan Zhang , Hong Chang Ji , Ramji Venkataramanan , Marco Mondelli

By using a time-dependent operator converting a distribution function (statistical operator) of a total system under consideration into the relevant form, new exact nonlinear generalized master equations (GMEs) are derived. The…

Statistical Mechanics · Physics 2007-05-23 Victor F. Los

We focus on the problem of estimating the change in the dependency structures of two $p$-dimensional Gaussian Graphical models (GGMs). Previous studies for sparse change estimation in GGMs involve expensive and difficult non-smooth…

Machine Learning · Computer Science 2018-05-24 Beilun Wang , Arshdeep Sekhon , Yanjun Qi

Electroencephalogram (EEG) signals generally exhibit low signal-to-noise ratio (SNR) and high inter-subject variability, making generalization across subjects and domains challenging. Recent advances in deep learning, particularly…

Machine Learning · Computer Science 2026-04-08 Jiazhen Hong , Geoffrey Mackellar , Soheila Ghane