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Clinical notes contain unstructured text provided by clinicians during patient encounters. These notes are usually accompanied by a sequence of diagnostic codes following the International Classification of Diseases (ICD). Correctly…

Machine Learning · Computer Science 2025-10-17 Mohammad Mansoori , Amira Soliman , Farzaneh Etminani

Automatic ICD coding is defined as assigning disease codes to electronic medical records (EMRs). Existing methods usually apply label attention with code representations to match related text snippets. Unlike these works that model the…

Computation and Language · Computer Science 2022-04-01 Zheng Yuan , Chuanqi Tan , Songfang Huang

Mapping clinical documents to standardised clinical vocabularies is an important task, as it provides structured data for information retrieval and analysis, which is essential to clinical research, hospital administration and improving…

Computation and Language · Computer Science 2025-09-15 Mingyang Li , Viktor Schlegel , Tingting Mu , Warren Del-Pinto , Goran Nenadic

Clinical auditing requires codified data for aggregation and analysis of patterns. However in the medical domain obtaining structured data can be difficult as the most natural, expressive and comprehensive way to record a clinical encounter…

Computers and Society · Computer Science 2016-06-14 Sedigheh Khademi , Christopher Palmer , Pari Delir Haghighi , Philip Lewis , Frada Burstein

ICD coding is the process of mapping unstructured text from Electronic Health Records (EHRs) to standardised codes defined by the International Classification of Diseases (ICD) system. In order to promote trust and transparency, existing…

Artificial Intelligence · Computer Science 2026-03-13 Mingyang Li , Viktor Schlegel , Tingting Mu , Wuraola Oyewusi , Kai Kang , Goran Nenadic

The reuse of historical clinical trial data has significant potential to accelerate medical research and drug development. However, interoperability challenges, particularly with missing medical codes, hinders effective data integration…

Machine Learning · Computer Science 2025-03-14 Nabeel Seedat , Caterina Tozzi , Andrea Hita Ardiaca , Mihaela van der Schaar , James Weatherall , Adam Taylor

International Classification of Diseases (ICD) is a global medical classification system which provides unique codes for diagnoses and procedures appropriate to a patient's clinical record. However, manual coding by human coders is…

Machine Learning · Computer Science 2022-11-17 Daeseong Kim , Haanju Yoo , Sewon Kim

Large Language Model (LLM)-based agents have demonstrated strong capabilities across a wide range of tasks, and their application in the medical domain holds particular promise due to the demand for high generalizability and reliance on…

Artificial Intelligence · Computer Science 2025-08-18 Yangyang Zhuang , Wenjia Jiang , Jiayu Zhang , Ze Yang , Joey Tianyi Zhou , Chi Zhang

Adapting production-level computer vision tools to bespoke scientific datasets is a critical "last mile" bottleneck. Current solutions are impractical: fine-tuning requires large annotated datasets scientists often lack, while manual code…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Xuefei , Wang , Kai A. Horstmann , Ethan Lin , Jonathan Chen , Alexander R. Farhang , Sophia Stiles , Atharva Sehgal , Jonathan Light , David Van Valen , Yisong Yue , Jennifer J. Sun

Clinical diagnosis, which aims to assign diagnosis codes for a patient based on the clinical note, plays an essential role in clinical decision-making. Considering that manual diagnosis could be error-prone and time-consuming, many…

Computation and Language · Computer Science 2021-01-28 Yichao Du , Pengfei Luo , Xudong Hong , Tong Xu , Zhe Zhang , Chao Ren , Yi Zheng , Enhong Chen

Automatic ICD coding, the task of assigning disease and procedure codes to electronic medical records, is crucial for clinical documentation and billing. While existing methods primarily enhance model understanding of code hierarchies and…

Computation and Language · Computer Science 2025-11-11 Tuan-Dung Le , Shohreh Haddadan , Thanh Q. Thieu

Large Language Models (LLMs) have fundamentally transformed approaches to Natural Language Processing (NLP) tasks across diverse domains. In healthcare, accurate and cost-efficient text classification is crucial, whether for clinical notes…

Computation and Language · Computer Science 2026-02-16 Hajar Sakai , Sarah S. Lam

Medical coding is a complex task, requiring assignment of a subset of over 72,000 ICD codes to a patient's notes. Modern natural language processing approaches to these tasks have been challenged by the length of the input and size of the…

Machine Learning · Computer Science 2022-08-17 Jay DeYoung , Han-Chin Shing , Luyang Kong , Christopher Winestock , Chaitanya Shivade

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

While Large Language Models (LLMs) have demonstrated potential in healthcare, they often struggle with the complex, non-linear reasoning required for accurate clinical diagnosis. Existing methods typically rely on static, linear mappings…

Computation and Language · Computer Science 2026-05-28 Zhuohan Ge , Haoyang Li , Yubo Wang , Nicole Hu , Chen Jason Zhang , Qing Li

Linking clinical narratives to standardized vocabularies and coding systems is a key component of unlocking the information in medical text for analysis. However, many domains of medical concepts lack well-developed terminologies that can…

Computation and Language · Computer Science 2021-03-11 Denis Newman-Griffis , Eric Fosler-Lussier

Biomedical research results are being published at a high rate, and with existing search engines, the vast amount of published work is usually easily accessible. However, reproducing published results, either experimental data or…

Molecular Networks · Quantitative Biology 2017-06-19 Kai-Wen Liang , Qinsi Wang , Cheryl Telmer , Divyaa Ravichandran , Peter Spirtes , Natasa Miskov-Zivanov

The task of assigning diagnostic ICD codes to patient hospital admissions is typically performed by expert human coders. Efforts towards automated ICD coding are dominated by supervised deep learning models. However, difficulties in…

Artificial Intelligence · Computer Science 2023-11-14 Joseph S. Boyle , Antanas Kascenas , Pat Lok , Maria Liakata , Alison Q. O'Neil

A ubiquitous task in processing electronic medical data is the assignment of standardized codes representing diagnoses and/or procedures to free-text documents such as medical reports. This is a difficult natural language processing task…

Artificial Intelligence (AI) is making a major impact on healthcare, particularly through its application in natural language processing (NLP) and predictive analytics. The healthcare sector has increasingly adopted AI for tasks such as…

Databases · Computer Science 2025-06-02 Karan Hanswadkar , Anika Kanchi , Shivani Tripathi , Shi Qiao , Rony Chatterjee , Alekh Jindal