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Emerging reasoning models hold promise for automating scientific discovery. However, their training is hindered by a critical supervision gap: experimental outcomes are abundant, whereas intermediate reasoning steps are rarely documented at…

Biomolecules · Quantitative Biology 2026-03-24 Zequn Liu , Kehan Wu , Shufang Xie , Zekun Guo , Wei Zhang , Tao Qin , Renhe Liu , Yingce Xia

Rule-based reasoning over natural language input arises in domains where decisions must be auditable and justifiable: clinical protocols specify eligibility criteria in prose, evidence rules define admissibility through textual conditions,…

Artificial Intelligence · Computer Science 2026-01-06 Albert Sadowski , Jarosław A. Chudziak

Large language models (LLMs) often generate hallucinations -- unsupported content that undermines reliability. While most prior works frame hallucination detection as a binary task, many real-world applications require identifying…

Clinical Decision Support Systems (CDSS) utilize evidence-based knowledge and patient data to offer real-time recommendations, with Large Language Models (LLMs) emerging as a promising tool to generate plain-text explanations for medical…

Computation and Language · Computer Science 2023-10-04 D. Umerenkov , G. Zubkova , A. Nesterov

Recent advances in large language models (LLMs) have revolutionized the landscape of reasoning tasks. To enhance the capabilities of LLMs to emulate human reasoning, prior studies have focused on modeling reasoning steps using various…

Artificial Intelligence · Computer Science 2024-05-28 Hongda Sun , Weikai Xu , Wei Liu , Jian Luan , Bin Wang , Shuo Shang , Ji-Rong Wen , Rui Yan

Reinforcement Learning (RL) is essential for evolving Large Language Models (LLMs) into autonomous agents capable of long-horizon planning, yet a practical recipe for scaling RL in complex, multi-turn environments remains elusive. This…

Machine Learning · Computer Science 2026-03-24 Xixi Wu , Qianguo Sun , Ruiyang Zhang , Chao Song , Junlong Wu , Yiyan Qi , Hong Cheng

Large Language Models (LLMs) have demonstrated potential in predicting mental health outcomes from online text, yet traditional classification methods often lack interpretability and robustness. This study evaluates structured reasoning…

Computation and Language · Computer Science 2026-01-09 Avinash Patil , Amardeep Kour Gedhu

Clinical Decision Support Systems (CDSSs) provide reasoning and inquiry guidance for physicians, yet they face notable challenges, including high maintenance costs and low generalization capability. Recently, Large Language Models (LLMs)…

Computation and Language · Computer Science 2026-04-24 Yue Guo , Fanfu Wang , Jianwei Lv , Xincheng Shi , Yuchen Li , Youya Wang , Yunsheng Zeng , Yujing Liu , Yunhao Qiao , Gen Li , Junfeng Wang , Bo Yuan

The emergence of vision-language models (VLMs) has opened new possibilities for clinical reasoning and has shown promising performance in dermatological diagnosis. However, their trustworthiness and clinical utility are often limited by…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Zehao Liu , Wejieying Ren , Jipeng Zhang , Tianxiang Zhao , Jingxi Zhu , Xiaoting Li , Vasant G. Honavar

Large Language Models (LLMs) have demonstrated impressive performance across various tasks, yet they remain vulnerable to generating toxic content, necessitating detoxification strategies to ensure safe and responsible deployment. Test-time…

Computation and Language · Computer Science 2025-10-03 Yisong Xiao , Aishan Liu , Siyuan Liang , Zonghao Ying , Xianglong Liu , Dacheng Tao

This paper addresses the challenges posed by the unstructured nature and high-dimensional semantic complexity of electronic health record texts. A deep learning method based on attention mechanisms is proposed to achieve unified modeling…

Computation and Language · Computer Science 2025-07-03 Ting Xu , Xiaoxiao Deng , Xiandong Meng , Haifeng Yang , Yan Wu

Large language models (LLMs) continue to struggle with knowledge-intensive questions that require up-to-date information and multi-hop reasoning. Augmenting LLMs with hybrid external knowledge, such as unstructured text and structured…

Machine Learning · Computer Science 2026-02-12 Junhong Lin , Bing Zhang , Song Wang , Ziyan Liu , Dan Gutfreund , Julian Shun , Yada Zhu

Enhancing reasoning capabilities remains a central focus in the LLM reasearch community. A promising direction involves requiring models to simulate code execution step-by-step to derive outputs for given inputs. However, as code is often…

Computation and Language · Computer Science 2025-07-15 Keqin Bao , Nuo Chen , Xiaoyuan Li , Binyuan Hui , Bowen Yu , Fuli Feng , Xiangnan He , Dayiheng Liu

Reinforcement learning with verifiable rewards (RLVR) has demonstrated superior performance in enhancing the reasoning capability of large language models (LLMs). However, this accuracy-oriented learning paradigm often suffers from entropy…

Artificial Intelligence · Computer Science 2026-01-19 Hongye Cao , Zhixin Bai , Ziyue Peng , Boyan Wang , Tianpei Yang , Jing Huo , Yuyao Zhang , Yang Gao

The growing complexity of log data in modern software systems has prompted the use of Large Language Models (LLMs) for automated log analysis. Current approaches typically rely on direct supervised fine-tuning (SFT) on log-label pairs.…

Reinforcement learning (RL)-based dynamic treatment regimes (DTRs) hold promise for automating complex clinical decision-making, yet their practical deployment remains hindered by the intensive engineering required to inject clinical…

Machine Learning · Computer Science 2025-08-08 Zhiyao Luo , Tingting Zhu

Reinforcement learning has become a central paradigm for improving LLM reasoning, but most existing methods optimize policies over discrete token sequences. This creates a mismatch between the optimization space and the structure of…

Machine Learning · Computer Science 2026-05-19 Haoqiang Kang , Yizhe Zhang , Nikki Lijing Kuang , Yi-An Ma , Lianhui Qin

Reasoning-focused large language models (LLMs) are rapidly evolving across various domains, yet their capabilities in handling complex legal problems remains underexplored. In this paper, we introduce Unilaw-R1, a large language model…

Computation and Language · Computer Science 2025-12-09 Hua Cai , Shuang Zhao , Liang Zhang , Xuli Shen , Qing Xu , Weilin Shen , Zihao Wen , Tianke Ban

Clinical decision-making is a dynamic, interactive, and cyclic process where doctors have to repeatedly decide on which clinical action to perform and consider newly uncovered information for diagnosis and treatment. Large Language Models…

Computation and Language · Computer Science 2026-03-03 David Bani-Harouni , Chantal Pellegrini , Ege Özsoy , Nassir Navab , Matthias Keicher

In-Context Reinforcement Learning (ICRL) enables Large Language Models (LLMs) to learn online from external rewards directly within the context window. However, a central challenge in ICRL is reward estimation, as models typically lack…

Computation and Language · Computer Science 2026-04-02 Wenxuan Jiang , Yuxin Zuo , Zijian Zhang , Xuecheng Wu , Zining Fan , Wenxuan Liu , Li Chen , Xiaoyu Li , Xuezhi Cao , Xiaolong Jin , Ninghao Liu
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