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Related papers: Bioinspired123D: Generative 3D Modeling System for…

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Drug development is a critical but notoriously resource- and time-consuming process. In this manuscript, we develop a novel generative artificial intelligence (genAI) method DiffSMol to facilitate drug development. DiffSmol generates 3D…

Machine Learning · Computer Science 2025-02-11 Ziqi Chen , Bo Peng , Tianhua Zhai , Daniel Adu-Ampratwum , Xia Ning

Generative AI has the potential to revolutionize drug discovery. Yet, despite recent advances in deep learning, existing models cannot generate molecules that satisfy all desired physicochemical properties. Herein, we describe IDOLpro, a…

Chemical Physics · Physics 2025-04-29 Amit Kadan , Kevin Ryczko , Erika Lloyd , Adrian Roitberg , Takeshi Yamazaki

Recent works on text-to-3d generation show that using only 2D diffusion supervision for 3D generation tends to produce results with inconsistent appearances (e.g., faces on the back view) and inaccurate shapes (e.g., animals with extra…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Cheng Chen , Xiaofeng Yang , Fan Yang , Chengzeng Feng , Zhoujie Fu , Chuan-Sheng Foo , Guosheng Lin , Fayao Liu

Shape-based virtual screening is widely employed in ligand-based drug design to search chemical libraries for molecules with similar 3D shapes yet novel 2D chemical structures compared to known ligands. 3D deep generative models have the…

Chemical Physics · Physics 2022-10-12 Keir Adams , Connor W. Coley

Generative models for 3D object synthesis have seen significant advancements with the incorporation of prior knowledge distilled from 2D diffusion models. Nevertheless, challenges persist in the form of multi-view geometric inconsistencies…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Lincong Feng , Muyu Wang , Maoyu Wang , Kuo Xu , Xiaoli Liu

Spider webs are incredible biological structures, comprising thin but strong silk filament and arranged into complex hierarchical architectures with striking mechanical properties (e.g., lightweight but high strength, achieving diverse…

Machine Learning · Computer Science 2023-04-12 Wei Lu , Nic A. Lee , Markus J. Buehler

While recent 3D generative models can produce high-quality texture images, they often fail to capture human preferences or meet task-specific requirements. Moreover, a core challenge in the 3D texture generation domain is that most existing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-10 AmirHossein Zamani , Tianhao Xie , Amir G. Aghdam , Tiberiu Popa , Eugene Belilovsky

With advancements in deep model architectures, tasks in computer vision can reach optimal convergence provided proper data preprocessing and model parameter initialization. However, training on datasets with low feature-richness for complex…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Dom Huh , Sai Gurrapu , Frederick Olson , Huzefa Rangwala , Parth Pathak , Jana Kosecka

With the recent development of generative models, Text-to-3D generations have also seen significant growth, opening a door for creating video-game 3D assets from a more general public. Nonetheless, people without any professional 3D editing…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Zhaoning Wang , Ming Li , Chen Chen

3D generative modeling is accelerating as the technology allowing the capture of geometric data is developing. However, the acquired data is often inconsistent, resulting in unregistered meshes or point clouds. Many generative learning…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Thomas Besnier , Sylvain Arguillère , Emery Pierson , Mohamed Daoudi

Computer-Aided Design (CAD) generative modeling is driving significant innovations across industrial applications. Recent works have shown remarkable progress in creating solid models from various inputs such as point clouds, meshes, and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Feiwei Qin , Shichao Lu , Junhao Hou , Changmiao Wang , Meie Fang , Ligang Liu

3D content creation plays a vital role in various applications, such as gaming, robotics simulation, and virtual reality. However, the process is labor-intensive and time-consuming, requiring skilled designers to invest considerable effort…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Chenhan Jiang

Diffusion-based text-to-image models ignited immense attention from the vision community, artists, and content creators. Broad adoption of these models is due to significant improvement in the quality of generations and efficient…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Tianfu Wang , Menelaos Kanakis , Konrad Schindler , Luc Van Gool , Anton Obukhov

For architectural design, representation across multiple Levels of Details (LoD) is essential for achieving a smooth transition from conceptual massing to detailed modeling. However, traditional LoD modeling processes rely on manual…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Xusheng Du , Athiwat Kongkaeo , Ye Zhang , Haoran Xie

Mechanical metamaterials enable precise control over structural properties, but their design method remains challenging due to their complex structure. Although additive manufacturing has expanded geometric freedom, navigating this vast and…

Soft Condensed Matter · Physics 2025-09-18 Kijung Kim , Seungwook Hong , Wonjun Jung , Wooseok Kim , Namjung Kim , Howon Lee

Text-to-3D generation is to craft a 3D object according to a natural language description. This can significantly reduce the workload for manually designing 3D models and provide a more natural way of interaction for users. However, this…

Computer Vision and Pattern Recognition · Computer Science 2023-09-27 Han Yi , Zhedong Zheng , Xiangyu Xu , Tat-seng Chua

Industrial computer vision systems often struggle with noise, material variability, and uncontrolled imaging conditions, limiting the effectiveness of classical edge detectors and handcrafted pipelines. In this work, we present a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Liang Gong , Tommy , Wang , Sara Chaker , Yanchen Dong , Fouad Bousetouane , Brenden Morton , Mark Mendez

Recently, text-to-image generation has exhibited remarkable advancements, with the ability to produce visually impressive results. In contrast, text-to-3D generation has not yet reached a comparable level of quality. Existing methods…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Yukang Cao , Yan-Pei Cao , Kai Han , Ying Shan , Kwan-Yee K. Wong

AI is increasingly used to accelerate engineering design by improving decision-making and shortening iteration cycles. Application to marine propeller design, however, remains challenging due to scarce training data and the lack of widely…

Computational Engineering, Finance, and Science · Computer Science 2026-04-27 Leah Chen , Keni Chih-Hua Wu , Boon Tat Chia , Xiuqing Xing , Jian Cheng Wong

If a picture is worth thousand words, a moving 3d shape must be worth a million. We build upon the success of recent generative methods that create images fitting the semantics of a text prompt, and extend it to the controlled generation of…

Machine Learning · Computer Science 2021-09-28 Nikolay Jetchev