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Head and neck squamous cell carcinoma (HNSCC) has one of the highest rates of recurrence cases among solid malignancies. Recurrence rates can be reduced by improving positive margins localization. Frozen section analysis (FSA) of resected…

Image and Video Processing · Electrical Eng. & Systems 2025-11-03 Qingyun Yang , Fangjie Li , Jiayi Xu , Zixuan Liu , Sindhura Sridhar , Whitney Jin , Jennifer Du , Jon Heiselman , Michael Miga , Michael Topf , Jie Ying Wu

Purpose: In this paper, we develop and clinically evaluate a depth-only, markerless augmented reality (AR) registration pipeline on a head-mounted display, and assess accuracy across small or low-curvature anatomies in real-life operative…

Computer Vision and Pattern Recognition · Computer Science 2025-11-05 Yue Yang , Fabian Necker , Christoph Leuze , Michelle Chen , Andrey Finegersh , Jake Lee , Vasu Divi , Bruce Daniel , Brian Hargreaves , Jie Ying Wu , Fred M Baik

Complete surgical resection of the tumor for Head and neck squamous cell carcinoma (HNSCC) remains challenging, given the devastating side effects of aggressive surgery and the anatomic proximity to vital structures. To address the clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Yong Hu , Shan Huang , Albert Y. Han , Seong Moon , Jeffrey F. Krane , Oscar Stafsudd , Warren Grundfest , Maie A. St. John

The use of Augmented Reality (AR) for navigation purposes has shown beneficial in assisting physicians during the performance of surgical procedures. These applications commonly require knowing the pose of surgical tools and patients to…

Over the last two decades, augmented reality (AR) has led to the rapid development of new interfaces in various fields of social and technological application domains. One such domain is medicine, and to a higher extent surgery, where these…

Human-Computer Interaction · Computer Science 2024-04-02 Jaime Sancho , Manuel Villa , Miguel Chavarrías , Eduardo Juarez , Alfonso Lagares , César Sanz

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

Augmented Reality (AR) has emerged as a significant advancement in surgical procedures, offering a solution to the challenges posed by traditional neuronavigation methods. These conventional techniques often necessitate surgeons to split…

Human-Computer Interaction · Computer Science 2023-11-06 Mahdi Bagheri , Farhad Piri , Hadi Digale , Saem Sattarzadeh , Mohammad Reza Mohammadi

Suboptimal interaction with patient data and challenges in mastering 3D anatomy based on ill-posed 2D interventional images are essential concerns in image-guided therapies. Augmented reality (AR) has been introduced in the operating rooms…

Computer Vision and Pattern Recognition · Computer Science 2020-03-05 Javad Fotouhi , Arian Mehrfard , Tianyu Song , Alex Johnson , Greg Osgood , Mathias Unberath , Mehran Armand , Nassir Navab

Purpose: Biopsies play a crucial role in determining the classification and staging of tumors. Ultrasound is frequently used in this procedure to provide real-time anatomical information. Using augmented reality (AR), surgeons can visualize…

Human-Computer Interaction · Computer Science 2024-12-19 Haowei Li , Wenqing Yan , Jiasheng Zhao , Yuqi Ji , Long Qian , Hui Ding , Zhe Zhao , Guangzhi Wang

Irreversible electroporation (IRE) is a soft tissue ablation technique suitable for treatment of inoperable tumours in the pancreas. The process involves applying a high voltage electric field to the tissue containing the mass using needle…

Purpose: To evaluate manual and automatic registration times as well as accuracy with augmented reality during alignment of a holographic 3-dimensional (3D) model onto the real-world environment. Method: 18 participants in various stages of…

Medical Physics · Physics 2020-12-07 Ningcheng Li , Jonathan Wakim , Yilun Koethe , Timothy Huber , Terence Gade , Stephen Hunt , Brian Park

The use of Augmented Reality (AR) devices for surgical guidance has gained increasing traction in the medical field. Traditional registration methods often rely on external fiducial markers to achieve high accuracy and real-time…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Yue Yang , Christoph Leuze , Brian Hargreaves , Bruce Daniel , Fred Baik

Within this thesis we propose a platform for combining Augmented Reality (AR) hardware with machine learning in a user-oriented pipeline, offering to the medical staff an intuitive 3D visualization of volumetric Computed Tomography (CT) and…

Computer Vision and Pattern Recognition · Computer Science 2018-08-16 Lucian Trestioreanu

Tumor volume segmentation on MRI is a challenging and time-consuming process that is performed manually in typical clinical settings. This work presents an approach to automated delineation of head and neck tumors on MRI scans, developed in…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Andrei Iantsen

Background and aim: Image registration and alignment are the main limitations of augmented reality-based knee replacement surgery. This research aims to decrease the registration error, eliminate outcomes that are trapped in local minima to…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Nitish Maharjan , Abeer Alsadoon , P. W. C. Prasad , Salma Abdullah , Tarik A. Rashid

In brain tumor resection, accurate removal of cancerous tissues while preserving eloquent regions is crucial to the safety and outcomes of the treatment. However, intra-operative tissue deformation (called brain shift) can move the surgical…

Image and Video Processing · Electrical Eng. & Systems 2023-07-28 Soorena Salari , Amirhossein Rasoulian , Hassan Rivaz , Yiming Xiao

Accurate intraoperative image guidance is critical for achieving maximal safe resection in brain tumor surgery, yet neuronavigation systems based on preoperative MRI lose accuracy during the procedure due to brain shift. Aligning…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Reuben Dorent , Laura Rigolo , Colin P. Galvin , Junyu Chen , Mattias P. Heinrich , Aaron Carass , Olivier Colliot , Demian Wassermann , Alexandra Golby , Tina Kapur , William Wells

Augmented Reality (AR) surgical navigation systems are emerging as the next generation of intraoperative surgical guidance, promising to overcome limitations of traditional navigation systems. However, known issues with AR depth perception…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Marc J. Fischer , Jeffrey Potts , Gabriel Urreola , Dax Jones , Paolo Palmisciano , E. Bradley Strong , Branden Cord , Andrew D. Hernandez , Julia D. Sharma , E. Brandon Strong

Arthroscopy is a minimally invasive surgical procedure used to diagnose and treat joint problems. The clinical workflow of arthroscopy typically involves inserting an arthroscope into the joint through a small incision, during which…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Hongchao Shu , Mingxu Liu , Lalithkumar Seenivasan , Suxi Gu , Ping-Cheng Ku , Jonathan Knopf , Russell Taylor , Mathias Unberath

The initial detection and identification of suspicious lesions and the precise delineation of tumour mar-gins are essential for successful tumour resection, with progression-free survival linked to rates of complete resection. However,…

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