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Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex,…

Recent advances in generative models, including large language models (LLMs), vision language models (VLMs), and diffusion models, have accelerated the field of natural language and image processing in medicine and marked a significant…

Large language models (LLMs) show promise in clinical decision support yet risk acquiescing to patient pressure for inappropriate care. We introduce SycoEval-EM, a multi-agent simulation framework evaluating LLM robustness through…

Artificial Intelligence · Computer Science 2026-03-05 Dongshen Peng , Yi Wang , Austin Schoeffler , Carl Preiksaitis , Christian Rose

Radiotherapy (RT) patient scheduling is a complex operational problem. Current scheduling often relies on manual coordination and can be difficult to adapt to changing clinical demands. This study evaluated the feasibility of using a large…

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

Writing has long been considered a hallmark of human intelligence and remains a pinnacle task for artificial intelligence (AI) due to the intricate cognitive processes involved. Recently, rapid advancements in generative AI, particularly…

Computation and Language · Computer Science 2024-11-06 Samar M. Magdy , Fakhraddin Alwajih , Sang Yun Kwon , Reem Abdel-Salam , Muhammad Abdul-Mageed

The recent swift development of LLMs like GPT-4, Gemini, and GPT-3.5 offers a transformative opportunity in medicine and healthcare, especially in digital diagnostics. This study evaluates each model diagnostic abilities by interpreting a…

Computation and Language · Computer Science 2024-05-14 Gaurav Kumar Gupta , Aditi Singh , Sijo Valayakkad Manikandan , Abul Ehtesham

Clinical trials are critical for drug development. Constructing the appropriate eligibility criteria (i.e., the inclusion/exclusion criteria for patient recruitment) is essential for the trial's success. Proper design of clinical trial…

Computation and Language · Computer Science 2023-10-10 Zifeng Wang , Cao Xiao , Jimeng Sun

Effective communication about breast and cervical cancers remains a persistent health challenge, with significant gaps in public understanding of cancer prevention, screening, and treatment, potentially leading to delayed diagnoses and…

Computation and Language · Computer Science 2025-05-19 Agnik Saha , Victoria Churchill , Anny D. Rodriguez , Ugur Kursuncu , Muhammed Y. Idris

Large language models (LLMs) are increasingly being used for complex research tasks such as literature review, idea generation, and scientific paper analysis, yet their ability to truly understand and process the intricate relationships…

Computation and Language · Computer Science 2025-06-11 Shashidhar Reddy Javaji , Yupeng Cao , Haohang Li , Yangyang Yu , Nikhil Muralidhar , Zining Zhu

In practice, clinicians achieve a diagnosis by following a sequence of steps, such as laboratory exams, observations, or imaging. The pathways to reach diagnosis decisions are documented by guidelines authored by expert organizations, which…

Computation and Language · Computer Science 2024-09-25 Elisa Castagnari , Lillian Muyama , Adrien Coulet

Clinical trials are crucial for assessing new treatments; however, recruitment challenges - such as limited awareness, complex eligibility criteria, and referral barriers - hinder their success. With the growth of online platforms, patients…

Information Retrieval · Computer Science 2025-04-30 Joey Chan , Qiao Jin , Nicholas Wan , Charalampos S. Floudas , Elisabetta Xue , Zhiyong Lu

Artificial intelligence (AI) has gained significant attention in healthcare consultation due to its potential to improve clinical workflow and enhance medical communication. However, owing to the complex nature of medical information, large…

Computation and Language · Computer Science 2024-03-05 Xiaolan Chen , Ziwei Zhao , Weiyi Zhang , Pusheng Xu , Le Gao , Mingpu Xu , Yue Wu , Yinwen Li , Danli Shi , Mingguang He

Procedural case logs are a core requirement in radiology training, yet they are time-consuming to complete and prone to inconsistency when authored manually. This study investigates whether large language models (LLMs) can automate…

Computation and Language · Computer Science 2026-01-21 Nafiz Imtiaz Khan , Kylie Cleland , Vladimir Filkov , Roger Eric Goldman

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

The increasing volume of research paper submissions poses a significant challenge to the traditional academic peer-review system, leading to an overwhelming workload for reviewers. This study explores the potential of integrating Large…

Artificial Intelligence · Computer Science 2024-12-03 Oscar Díaz , Xabier Garmendia , Juanan Pereira

Generative Artificial Intelligence (GenAI), particularly Large Language Models (LLMs), offer powerful capabilities for interpreting the complex data landscape in healthcare. In this paper, we present a comprehensive overview of the…

Machine Learning · Computer Science 2025-09-05 Ankit Shetgaonkar , Dipen Pradhan , Lakshit Arora , Sanjay Surendranath Girija , Shashank Kapoor , Aman Raj

Recent developments in large language models (LLMs) have unlocked new opportunities for healthcare, from information synthesis to clinical decision support. These new LLMs are not just capable of modeling language, but can also act as…

Human-Computer Interaction · Computer Science 2023-09-21 Nikita Mehandru , Brenda Y. Miao , Eduardo Rodriguez Almaraz , Madhumita Sushil , Atul J. Butte , Ahmed Alaa

The rapid growth of biomedical literature poses challenges for manual knowledge curation and synthesis. Biomedical Natural Language Processing (BioNLP) automates the process. While Large Language Models (LLMs) have shown promise in general…

The shortage of clinical workforce presents significant challenges in mental healthcare, limiting access to formal diagnostics and services. We aim to tackle this shortage by integrating a customized large language model (LLM) into the…

Computation and Language · Computer Science 2025-05-02 Sichang Tu , Abigail Powers , Natalie Merrill , Negar Fani , Sierra Carter , Stephen Doogan , Jinho D. Choi
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