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The progression of chronic diseases often follows highly variable trajectories, and the underlying factors remain poorly understood. Standard mixed-effects models typically represent inter-patient differences as random deviations around a…

Multiple outcomes, both continuous and discrete, are routinely gathered on subjects in longitudinal studies and during routine clinical follow-up in general. To motivate our work, we consider a longitudinal study on patients with primary…

Applications · Statistics 2013-04-17 Arnošt Komárek , Lenka Komárková

We present MIX'EM, a novel solution for unsupervised image classification. MIX'EM generates representations that by themselves are sufficient to drive a general-purpose clustering algorithm to deliver high-quality classification. This is…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Ali Varamesh , Tinne Tuytelaars

In this paper, we present an information-theoretic method for clustering mixed-type data, that is, data consisting of both continuous and categorical variables. The proposed approach extends the Information Bottleneck principle to…

Methodology · Statistics 2026-02-02 Efthymios Costa , Ioanna Papatsouma , Angelos Markos

The standard mixture modeling framework has been widely used to study heterogeneous populations, by modeling them as being composed of a finite number of homogeneous sub-populations. However, the standard mixture model assumes that each…

Methodology · Statistics 2025-08-05 Emiliano Seri , Roberto Rocci , Thomas Brendan Murphy

Data in the form of rankings, ratings, pair comparisons or clicks are frequently collected in diverse fields, from marketing to politics, to understand assessors' individual preferences. Combining such preference data with features…

Methodology · Statistics 2024-02-19 Emilie Eliseussen , Arnoldo Frigessi , Valeria Vitelli

Feature selection methods are widely used to address the high computational overheads and curse of dimensionality in classifying high-dimensional data. Most conventional feature selection methods focus on handling homogeneous features,…

Machine Learning · Computer Science 2021-11-17 Xuyang Yan , Mrinmoy Sarkar , Biniam Gebru , Shabnam Nazmi , Abdollah Homaifar

Spectral clustering has emerged as one of the most effective clustering algorithms due to its superior performance. However, most existing models are designed for centralized settings, rendering them inapplicable in modern decentralized…

Machine Learning · Computer Science 2026-04-17 Suyan Dai , Gan Sun , Fazeng Li , Xu Tang , Qianqian Wang , Yang Cong

Mixture models provide a flexible representation of heterogeneity in a finite number of latent classes. From the Bayesian point of view, Markov Chain Monte Carlo methods provide a way to draw inferences from these models. In particular,…

Methodology · Statistics 2020-05-06 Carolina Valani Cavalcante , Kelly Cristina Mota Gonçalves

Cluster analyses of high-dimensional data are often hampered by the presence of large numbers of variables that do not provide relevant information, as well as the perennial issue of choosing an appropriate number of clusters. These…

Computation · Statistics 2024-12-02 Emma Prevot , Rory Toogood , Filippo Pagani , Paul D. W. Kirk

Selective inference aims at providing valid inference after a data-driven selection of models or hypotheses. It is essential to avoid overconfident results and replicability issues. While significant advances have been made in this area for…

Methodology · Statistics 2025-03-14 Matteo D'Alessandro , Magne Thoresen

Functional mixed models are widely useful for regression analysis with dependent functional data, including longitudinal functional data with scalar predictors. However, existing algorithms for Bayesian inference with these models only…

Methodology · Statistics 2023-06-14 Thomas Y. Sun , Daniel R. Kowal

Statistical modelling in the presence of data organized in groups is a crucial task in Bayesian statistics. The present paper conceives a mixture model based on a novel family of Bayesian priors designed for multilevel data and obtained by…

Methodology · Statistics 2024-07-01 Alessandro Colombi , Raffaele Argiento , Federico Camerlenghi , Lucia Paci

Partially recorded data are frequently encountered in many applications and usually clustered by first removing incomplete cases or features with missing values, or by imputing missing values, followed by application of a clustering…

Methodology · Statistics 2021-10-20 Emily M. Goren , Ranjan Maitra

Term clustering is important in biomedical knowledge graph construction. Using similarities between terms embedding is helpful for term clustering. State-of-the-art term embeddings leverage pretrained language models to encode terms, and…

Computation and Language · Computer Science 2022-04-04 Sihang Zeng , Zheng Yuan , Sheng Yu

Handling missing data is a major challenge in model-based clustering, especially when the data exhibit skewness and heavy tails. We address this by extending the finite mixture of scale mixtures of multivariate skew-normal (FMSMSN) family…

Methodology · Statistics 2025-07-29 Jason Pillay , Cristina Tortora , Antonio Punzo , Andriette Bekker

High-throughput sequencing technology provides unprecedented opportunities to quantitatively explore human gut microbiome and its relation to diseases. Microbiome data are compositional, sparse, noisy, and heterogeneous, which pose serious…

Methodology · Statistics 2020-10-12 Fangting Zhou , Kejun He , Qiwei Li , Robert S. Chapkin , Yang Ni

Breast cancer is a significant global health issue, and the diagnosis of breast cancer through imaging remains challenging. Mammography images are characterized by extremely high resolution, while lesions often occupy only a small portion…

Tissues and Organs · Quantitative Biology 2025-07-28 Shilong Yang , Chulong Zhang , Xiaokun Liang , Qi Zang , Juan Yu , Liang Zeng , Xiao Luo , Yexuan Xing , Xin Pan , Qi Li , Linlin Shen , Yaoqin Xie

Choosing appropriate hyperparameters for unsupervised clustering algorithms in an optimal way depending on the problem under study is a long standing challenge, which we tackle while adapting clustering algorithms for immune disorder…

Quantitative Methods · Quantitative Biology 2020-09-25 A. Carpio , A. Simón , L. F. Villa

The Bayesian approach to inference stands out for naturally allowing borrowing information across heterogeneous populations, with different samples possibly sharing the same distribution. A popular Bayesian nonparametric model for…

Methodology · Statistics 2022-01-25 Antonio Lijoi , Igor Prünster , Giovanni Rebaudo