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Diabetic retinopathy is the leading cause of vision loss in working-age adults worldwide, yet under-resourced regions lack ophthalmologists. Current state-of-the-art deep learning systems struggle at these institutions due to limited…

Image and Video Processing · Electrical Eng. & Systems 2025-04-23 Gajan Mohan Raj , Michael G. Morley , Mohammad Eslami

Background: Cardiovascular diseases (CVDs) are the leading cause of death globally. The use of artificial intelligence (AI) methods - in particular, deep learning (DL) - has been on the rise lately for the analysis of different CVD-related…

Inherited retinal diseases (IRDs) are a diverse group of genetic disorders that lead to progressive vision loss and are a major cause of blindness in working-age adults. The complexity and heterogeneity of IRDs pose significant challenges…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Han Trinh , Jordan Vice , Jason Charng , Zahra Tajbakhsh , Khyber Alam , Fred K. Chen , Ajmal Mian

Diabetic retinopathy (DR) is caused by long-standing diabetes and is among the fifth leading cause for visual impairments. The process of early diagnosis and treatments could be helpful in curing the disease, however, the detection…

Computer Vision and Pattern Recognition · Computer Science 2023-10-30 Chamuditha Jayanga Galappaththige , Gayal Kuruppu , Muhammad Haris Khan

Retinal optical coherence tomography (OCT) images are the biomarkers for neurodegenerative diseases, which are rising in prevalence. Early detection of Alzheimer's disease using retinal OCT is a primary challenging task. This work utilizes…

Image and Video Processing · Electrical Eng. & Systems 2025-08-19 Siva Manohar Reddy Kesu , Neelam Sinha , Hariharan Ramasangu , Thomas Gregor Issac

A number of life threatening neuro-degenerative disorders had degraded the quality of life for the older generation in particular. Dementia is one such symptom which may lead to a severe condition called Alzheimer's disease if not detected…

Neural and Evolutionary Computing · Computer Science 2024-02-01 Anuvab Sen , Udayon Sen , Subhabrata Roy

A variety of vision ailments are associated with geographic atrophy (GA) in the foveal region of the eye. In current clinical practice, the ophthalmologist manually detects potential presence of such GA based on fundus autofluorescence…

Autism Spectrum Disorder (ASD) is a severe neuropsychiatric disorder that affects intellectual development, social behavior, and facial features, and the number of cases is still significantly increasing. Due to the variety of symptoms ASD…

Image and Video Processing · Electrical Eng. & Systems 2021-10-11 Ryan Liu , Spencer He

Despite the revolutionary impact of AI and the development of locally trained algorithms, achieving widespread generalized learning from multi-modal data in medical AI remains a significant challenge. This gap hinders the practical…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Fatema-E Jannat , Sina Gholami , Minhaj Nur Alam , Hamed Tabkhi

The automatic detection of disease related entities in retinal imaging data is relevant for disease- and treatment monitoring. It enables the quantitative assessment of large amounts of data and the corresponding study of disease…

Explainable Artificial Intelligence (AI) in the form of an interpretable and semiautomatic approach to stage grading ocular pathologies such as Diabetic retinopathy, Hypertensive retinopathy, and other retinopathies on the backdrop of major…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Ayushi Raj Bhatt , Rajkumar Vaghashiya , Meghna Kulkarni , Dr Prakash Kamaraj

In the medical domain, acquiring large datasets poses significant challenges due to privacy concerns. Nonetheless, the development of a robust deep-learning model for retinal disease diagnosis necessitates a substantial dataset for…

Computer Vision and Pattern Recognition · Computer Science 2024-09-18 Fatema-E- Jannat , Sina Gholami , Jennifer I. Lim , Theodore Leng , Minhaj Nur Alam , Hamed Tabkhi

Retinopathy of prematurity (ROP) is a severe condition affecting premature infants, leading to abnormal retinal blood vessel growth, retinal detachment, and potential blindness. While semi-automated systems have been used in the past to…

Eye diseases have posed significant challenges for decades, but advancements in technology have opened new avenues for their detection and treatment. Machine learning and deep learning algorithms have become instrumental in this domain,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Gauri Naik , Nandini Narvekar , Dimple Agarwal , Nishita Nandanwar , Himangi Pande

The automatic segmentation of retinal layer structures enables clinically-relevant quantification and monitoring of eye disorders over time in OCT imaging. Eyes with late-stage diseases are particularly challenging to segment, as their…

Computer Vision and Pattern Recognition · Computer Science 2017-07-18 Stefanos Apostolopoulos , Sandro De Zanet , Carlos Ciller , Sebastian Wolf , Raphael Sznitman

Among the most impactful diabetic complications are diabetic retinopathy, the leading cause of blindness among working class adults, and cardiovascular disease, the leading cause of death worldwide. This study describes the development of…

Medical Physics · Physics 2020-11-17 Kasyap Chakravadhanula

Optical Coherence Tomography (OCT) is the primary imaging modality for detecting pathological biomarkers associated to retinal diseases such as Age-Related Macular Degeneration. In practice, clinical diagnosis and treatment strategies are…

Computer Vision and Pattern Recognition · Computer Science 2019-07-17 Thomas Kurmann , Pablo Márquez-Neila , Siqing Yu , Marion Munk , Sebastian Wolf , Raphael Sznitman

Diabetic Retinopathy (DR) stands as the leading cause of blindness globally, particularly affecting individuals between the ages of 20 and 70. This paper presents a Computer-Aided Diagnosis (CAD) system designed for the automatic…

Computer Vision and Pattern Recognition · Computer Science 2024-08-31 Inas Al-Kamachy , Reza Hassanpour , Roya Choupani

Recent Alzheimer's disease (AD) patient studies have focused on retinal analysis, as the retina is the only part of the central nervous system which can be imaged non-invasively by optical methods. However as this is a relatively new…

Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Yasemin Turkan , F. Boray Tek , M. Serdar Nazlı , Öykü Eren