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The transport of biomolecules, drugs, or reactants encapsulated inside stimuli-responsive polymer networks in aqueous media is fundamental for many material and environmental science applications, including drug delivery, biosensing,…

A central quantity in the design of functional hydrogels used as nanocarrier systems, for instance for drug delivery or adaptive nanocatalysis, is the partition ratio, which quantifies the uptake of a molecular substance by the polymer…

Soft Condensed Matter · Physics 2019-01-08 Matej Kanduc , Won Kyu Kim , Rafael Roa , Joachim Dzubiella

The long debated protein dynamical transition was recently found also in non-biological macromolecules, such as poly-N-isopropylacrylamide (PNIPAM) microgels. Here, by using atomistic molecular dynamics simulations, we report a description…

Soft Condensed Matter · Physics 2019-03-14 Letizia Tavagnacco , Ester Chiessi , Marco Zanatta , Andrea Orecchini , Emanuela Zaccarelli

Interpenetrated Polymer Network (IPN) microgels of PNIPAM and PAAc have been investigated and the experimental data have been compared with theoretical models from the Flory-Rehner theory. We confirm that the swelling behavior of PNIPAM…

Soft Condensed Matter · Physics 2019-06-24 Valentina Nigro , Roberta Angelini , Monica Bertoldo , Barbara Ruzicka

Microgel suspensions of Interpenetrated Polymer Network (IPN) of PNIPAM and PAAc in D$_2$O, have been investigated through dynamic light scattering as a function of temperature, pH and concentration across the Volume Phase Transition (VPT).…

Poly(N-isopropylacrylamide) (pNIPAM) microgels are renowned for their thermoresponsive behavior, exhibiting a distinct volume phase transition (VPT) upon temperature changes. This study investigates the influence of microgel softness,…

Soft Condensed Matter · Physics 2024-08-06 Syamjith KS , Shubhasmita Rout , Alan R Jacob

Microgel particles composed of Interpenetrated Polymer Networks (IPN) of poly(N-isopropylacrylamide) (PNIPAM) and poly(acrylic acid) (PAAc) dispersed in water have been investigated through dynamic light scattering. The study of the…

Combining elastic incoherent neutron scattering and differential scanning calorimetry, we investigate the occurrence of the volume phase transition (VPT) in very concentrated PNIPAM microgel suspensions, from a polymer weight fraction of…

Soft Condensed Matter · Physics 2020-08-04 M. Zanatta , L. Tavagnacco , E. Buratti , E. Chiessi , F. Natali , M. Bertoldo , A. Orecchini , E. Zaccarelli

The combination of the catechol-containing co-monomer dopamine methacrylamide (DMA) with stimuli-responsive microgels such as poly(N-isopropylacrylamide) (PNIPAM) bears a huge potential in research and for applications due to the versatile…

Soft Condensed Matter · Physics 2023-09-29 Sandra Forg , Xuhong Guo , Regine von Klitzing

Poly(N-isopropylacrylamide) (PNIPAM) is a synthetic polymer that is widely studied for its thermoresponsive character. However, recent works also reported evidence of a low temperature (protein-like) dynamical transition around 225 K in…

Methanol-water liquid mixtures have been investigated by high-energy synchrotron X-ray and neutron diffraction at low temperatures. We are thus able to report the first complete sets of both X-ray and neutron weighted total scattering…

The Angstrom-scale transport characteristics of water and six different solutes, methanol, ethanol, 2-propanol, urea, Na+, and Cl-, were studied for a polyamide reverse osmosis (RO) membrane, FT-30, using non-equilibrium molecular dynamics…

Computational Physics · Physics 2016-07-18 Meng Shen , Sinan Keten , Richard M. Lueptow

A low-temperature dynamical transition has been reported in several proteins. We provide the first observation of a `protein-like' dynamical transition in nonbiological aqueous environments. To this aim we exploit the popular colloidal…

Colloidal microgel particles such as poly(N-isopropylacrylamide) (PNIPAM) shrink reversibly in an aqueous medium due to the expulsion of water at a volume phase transition temperature, VPTT $\sim$33$^\circ$C. Romeo et al. [Adv. Mater. 2010,…

Soft Condensed Matter · Physics 2025-11-06 Sayantan Chanda , Chandeshwar Misra , Ranjini Bandyopadhyay

We combine small angle scattering experiments and simulations to investigate the internal structure and interactions of composite Poly(N-isopropylacrylamide)-Poly(ethylene glycol) (PNIPAM-PEG) microgels. At low temperatures the…

The influence of shape fluctuations on deformable thermosensitive microgels in aqueous solution is investigated by dynamic light scattering (DLS) and depolarized dynamic light scattering (DDLS). The systems under study consist of a solid…

Soft Condensed Matter · Physics 2009-02-20 S. Bolisetty , M. Hoffmann , S. Lekkala , Th. Hellweg , M. Ballauff , L. Harnau

As a novel stimulus, we used high-frequency ultrasonic waves to provide the required energy for breaking hydrogen bonds between Poly(N-isopropylacrylamide) (PNIPAM) and water molecules while the solution temperature maintains below the…

Soft Condensed Matter · Physics 2023-11-15 Atieh Razavi , Matthias Rutsch , Sonja Wismath , Mario Kupnik , Regine von Klitzing , Amin Rahimzadeh

Hydrogel-based soft actuators can operate in sensitive environments, bridging the gap of rigid machines interacting with soft matter. However, while stimuli-responsive hydrogels can undergo extreme reversible volume changes of up to ~90%,…

Responsive microgels based on poly(N-isopropylacrylamide) (PNIPAM) exhibit peculiar behaviours due to the competition between the hydrophilic and hydrophobic interactions of the constituent networks. The interpenetration of poly-acrilic…

In this study some properties of the methanol-water mixture such as diffusivity, density, viscosity, and hydrogen bonding were calculated at different temperatures and atmospheric pressure using molecular dynamics simulations (MDS). The…

Atomic and Molecular Clusters · Physics 2017-08-08 Palazzo Mancini , Mara Cantoni
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