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Left ventricular ejection fraction (LVEF) assessment depends on echocardiography, limiting access in primary care and resource-constrained settings. We developed a multimodal machine-learning framework that combines engineered 12-lead ECG…

Machine Learning · Computer Science 2026-04-30 Catherine Ning , Yu Ma , Cindy Beini Wang , Sean McMahon , Joseph Radojevic , Steven Zweibel , Dimitris Bertsimas

Artificial intelligence-enabled electrocardiography (AI-ECG) can detect heart failure (HF), including disease not captured by left ventricular ejection fraction (LVEF), but the cardiac phenotypes underlying model predictions remain unclear.…

Artificial Intelligence · Computer Science 2026-05-26 Elias Stenhede , Eivind Bjørkan Orstad , Torbjørn Omland , Henrik Schirmer , Arian Ranjbar

Ejection fraction (EF) of the left ventricle (LV) is considered as one of the most important measurements for diagnosing acute heart failure and can be estimated during cardiac ultrasound acquisition. While recent successes in deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Sarina Thomas , Qing Cao , Anna Novikova , Daria Kulikova , Guy Ben-Yosef

Left ventricular ejection fraction (LVEF) is a key indicator of cardiac function and plays a central role in the diagnosis and management of cardiovascular disease. Echocardiography, as a readily accessible and non-invasive imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Shravan Saranyan , Pramit Saha

The echocardiographic measurement of left ventricular ejection fraction (LVEF) is fundamental to the diagnosis and classification of patients with heart failure (HF). In order to quantify LVEF automatically and accurately, this paper…

Accurate LVEF measurement is important in clinical practice as it identifies patients who may be in need of life-prolonging treatments. This paper presents a deep learning based framework to automatically estimate left ventricular ejection…

Image and Video Processing · Electrical Eng. & Systems 2023-04-18 Meghan Muldoon , Naimul Khan

Structural heart disease (SHD) is a prevalent condition with many undiagnosed cases, and early detection is often limited by the high cost and accessibility constraints of echocardiography (ECHO). Recent studies show that artificial…

Applications · Statistics 2026-03-04 Ya Zhou , Zhaohong Sun , Tianxiang Hao , Xiangjie Li

Ejection fraction (EF) is a key indicator of cardiac function, allowing identification of patients prone to heart dysfunctions such as heart failure. EF is estimated from cardiac ultrasound videos known as echocardiograms (echo) by manually…

Image and Video Processing · Electrical Eng. & Systems 2023-07-25 Masoud Mokhtari , Teresa Tsang , Purang Abolmaesumi , Renjie Liao

Artificial intelligence-enhanced electrocardiogram (AI-ECG) has shown promise as an inexpensive, ubiquitous, and non-invasive screening tool to detect left ventricular systolic dysfunction in pediatric congenital heart disease. However,…

Computational Engineering, Finance, and Science · Computer Science 2025-11-14 Yuting Yang , Lorenzo Peracchio , Joshua Mayourian , John K. Triedman , Timothy Miller , William G. La Cava

Echocardiography is a cornerstone for managing heart failure (HF), with Left Ventricular Ejection Fraction (LVEF) being a critical metric for guiding therapy. However, manual LVEF assessment suffers from high inter-observer variability,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Jyun-Ping Kao , Jiaxin Yang , C. -C. Jay Kuo , Jonghye Woo

The electrocardiogram or ECG has been in use for over 100 years and remains the most widely performed diagnostic test to characterize cardiac structure and electrical activity. We hypothesized that parallel advances in computing power,…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Geoffrey H. Tison , Jeffrey Zhang , Francesca N. Delling , Rahul C. Deo

Conventional task-specific electrocardiogram (ECG) analysis models require large annotated datasets to train. Foundation models mitigate this burden by leveraging self-supervised pretraining; however, the scarcity of open-weight ECG…

Machine Learning · Computer Science 2025-06-02 Kaden McKeen , Sameer Masood , Augustin Toma , Barry Rubin , Bo Wang

The electrocardiogram (ECG) is a key diagnostic tool in cardiovascular health. Single-lead ECG recording is integrated into both clinical-grade and consumer wearables. While self-supervised pretraining of foundation models on unlabeled ECGs…

Machine Learning · Computer Science 2025-12-03 Yuxuan Shu , Peter H. Charlton , Fahim Kawsar , Jussi Hernesniemi , Mohammad Malekzadeh

Timely access to laboratory values is critical for clinical decision-making, yet current approaches rely on invasive venous sampling and are intrinsically delayed. Electrocardiography (ECG), as a non-invasive and widely available signal,…

Machine Learning · Computer Science 2025-10-28 Yujie Xiao , Gongzhen Tang , Wenhui Liu , Jun Li , Guangkun Nie , Zhuoran Kan , Deyun Zhang , Qinghao Zhao , Shenda Hong

Objective To develop a robust and computationally efficient deep learning model for automated left ventricular ejection fraction (LVEF) estimation from echocardiography videos that is suitable for real-time point-of-care ultrasound (POCUS)…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 Moein Heidari , Afshin Bozorgpour , AmirHossein Zarif-Fakharnia , Wenjin Chen , Dorit Merhof , David J Foran , Jasmine Grewal , Ilker Hacihaliloglu

Accurate and consistent predictions of echocardiography parameters are important for cardiovascular diagnosis and treatment. In particular, segmentations of the left ventricle can be used to derive ventricular volume, ejection fraction (EF)…

Computer Vision and Pattern Recognition · Computer Science 2022-07-07 Sarina Thomas , Andrew Gilbert , Guy Ben-Yosef

Electrocardiography (ECG) is a low-cost, widely used modality for diagnosing electrical abnormalities like atrial fibrillation by capturing the heart's electrical activity. However, it cannot directly measure cardiac morphological…

Machine Learning · Computer Science 2026-03-10 Michelle Espranita Liman , Özgün Turgut , Alexander Müller , Eimo Martens , Daniel Rueckert , Philip Müller

Left-ventricular ejection fraction (LVEF) is an important indicator of heart failure. Existing methods for LVEF estimation from video require large amounts of annotated data to achieve high performance, e.g. using 10,030 labeled…

Computer Vision and Pattern Recognition · Computer Science 2022-12-19 Weihang Dai , Xiaomeng Li , Xinpeng Ding , Kwang-Ting Cheng

The electrocardiogram (ECG) is an inexpensive and widely available tool for cardiac assessment. Despite its standardized format and small file size, the high complexity and inter-individual variability of ECG signals (typically a…

Machine Learning · Computer Science 2025-08-04 Christopher Harvey , Sumaiya Shomaji , Zijun Yao , Amit Noheria

Objective: To develop and interpret a supervised variational autoencoder (VAE) model for classifying cardiotocography (CTG) signals based on pregnancy outcomes, addressing interpretability limits of current deep learning approaches.…

Machine Learning · Computer Science 2025-09-09 John Tolladay , Beth Albert , Gabriel Davis Jones
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