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Achieving robust performance and fairness across diverse patient populations remains a challenge in developing clinically deployable deep learning models for diagnostic imaging. Synthetic data generation has emerged as a promising strategy…

Diffusion and Poisson flow models have shown impressive performance in a wide range of generative tasks, including low-dose CT image denoising. However, one limitation in general, and for clinical applications in particular, is slow…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Dennis Hein , Staffan Holmin , Timothy Szczykutowicz , Jonathan S Maltz , Mats Danielsson , Ge Wang , Mats Persson

Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) are the predominant modalities utilized in the field of medical imaging. Although MRI capture the complexity of anatomical structures with greater detail than CT, it entails a…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Zhenbin Wang , Lei Zhang , Lituan Wang , Zhenwei Zhang

Magnetic resonance (MR)-to-computed tomography (CT) translation offers significant advantages, including the elimination of radiation exposure associated with CT scans and the mitigation of imaging artifacts caused by patient motion. The…

Image and Video Processing · Electrical Eng. & Systems 2025-08-08 Chaohui Gong , Zhiying Wu , Zisheng Huang , Gaofeng Meng , Zhen Lei , Hongbin Liu

We propose a method for synthesizing cardiac magnetic resonance (MR) images with plausible heart pathologies and realistic appearances for the purpose of generating labeled data for the application of supervised deep-learning (DL) training.…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Sina Amirrajab , Cristian Lorenz , Juergen Weese , Josien Pluim , Marcel Breeuwer

This study investigates the foundational characteristics of image-to-image translation networks, specifically examining their suitability and transferability within the context of routine clinical environments, despite achieving high levels…

Image and Video Processing · Electrical Eng. & Systems 2024-07-29 Mohammad R. Salmanpour , Amin Mousavi , Yixi Xu , William B Weeks , Ilker Hacihaliloglu

Magnetic Resonance Imaging (MRI) enables the acquisition of multiple image contrasts, such as T1-weighted (T1w) and T2-weighted (T2w) scans, each offering distinct diagnostic insights. However, acquiring all desired modalities increases…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Andrea Moschetto , Lemuel Puglisi , Alec Sargood , Pierluigi Dell'Acqua , Francesco Guarnera , Sebastiano Battiato , Daniele Ravì

Diffusion-based image generators are promising priors for ill-posed inverse problems like sparse-view X-ray Computed Tomography (CT). As most studies consider synthetic data, it is not clear whether training data mismatch (``domain shift'')…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Nelas J. Thomsen , Xinyuan Wang , Felix Lucka , Ezgi Demircan-Tureyen

We study the problem of synthesizing a number of likely future frames from a single input image. In contrast to traditional methods, which have tackled this problem in a deterministic or non-parametric way, we propose a novel approach that…

Computer Vision and Pattern Recognition · Computer Science 2016-07-12 Tianfan Xue , Jiajun Wu , Katherine L. Bouman , William T. Freeman

The generation of Synthetic Computed Tomography (sCT) images has become a pivotal methodology in modern clinical practice, particularly in the context of Radiotherapy (RT) treatment planning. The use of sCT enables the calculation of doses,…

By decomposing the image formation process into a sequential application of denoising autoencoders, diffusion models (DMs) achieve state-of-the-art synthesis results on image data and beyond. Additionally, their formulation allows for a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Robin Rombach , Andreas Blattmann , Dominik Lorenz , Patrick Esser , Björn Ommer

Generative modelling and synthetic data can be a surrogate for real medical imaging datasets, whose scarcity and difficulty to share can be a nuisance when delivering accurate deep learning models for healthcare applications. In recent…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Virginia Fernandez , Walter Hugo Lopez Pinaya , Pedro Borges , Mark S. Graham , Tom Vercauteren , M. Jorge Cardoso

Computed tomography (CT) equivalent information is needed for attenuation correction in PET imaging and for dose planning in radiotherapy. Prior work has shown that Gaussian mixture models can be used to generate a substitute CT (s-CT)…

Applications · Statistics 2016-09-29 Anders Hildeman , David Bolin , Jonas Wallin , Adam Johansson , Tufve Nyholm , Thomas Asklund , Jun Yu

Multi-sequence MRI is valuable in clinical settings for reliable diagnosis and treatment prognosis, but some sequences may be unusable or missing for various reasons. To address this issue, MRI synthesis is a potential solution. Recent deep…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Luyi Han , Tianyu Zhang , Yunzhi Huang , Haoran Dou , Xin Wang , Yuan Gao , Chunyao Lu , Tan Tao , Ritse Mann

For millimeter wave (mmWave) massive multiple-input multiple-output (MIMO) systems, hybrid processing architecture is usually used to reduce the complexity and cost, which poses a very challenging issue in channel estimation. In this paper,…

Information Theory · Computer Science 2021-04-26 Peihao Dong , Hua Zhang , Geoffrey Ye Li , Ivan Simoes Gaspar , Navid NaderiAlizadeh

Contrast-enhanced (CE) T1-weighted MRI is central to neuro-oncologic diagnosis but requires gadolinium-based agents, which add cost and scan time, raise environmental concerns, and may pose risks to patients. In this work, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Bastian Brandstötter , Erich Kobler

Diffusion models (DMs) have shown remarkable capabilities in generating realistic high-quality images, audios, and videos. They benefit significantly from extensive pre-training on large-scale datasets, including web-crawled data with…

Computer Vision and Pattern Recognition · Computer Science 2024-10-31 Hao Chen , Yujin Han , Diganta Misra , Xiang Li , Kai Hu , Difan Zou , Masashi Sugiyama , Jindong Wang , Bhiksha Raj

Magnetic resonance imaging (MRI) is essential for nasopharyngeal carcinoma (NPC) radiotherapy (RT), but practical constraints, such as patient discomfort, long scan times, and high costs often lead to incomplete modalities in clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yao Pu , Yiming Shi , Zhenxi Zhang , Peixin Yu , Yitao Zhuang , Xiang Wang , Hongzhao Chen , Jing Cai , Ge Ren

Brain MRI scans are often found in four modalities, consisting of T1-weighted with and without contrast enhancement (T1ce and T1w), T2-weighted imaging (T2w), and Flair. Leveraging complementary information from these different modalities…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Bhavesh Sandbhor , Bheeshm Sharma , Balamurugan Palaniappan

Magnetic resonance imaging (MRI) is a widely used neuroimaging technique that can provide images of different contrasts (i.e., modalities). Fusing this multi-modal data has proven particularly effective for boosting model performance in…

Computer Vision and Pattern Recognition · Computer Science 2020-02-13 Tao Zhou , Huazhu Fu , Geng Chen , Jianbing Shen , Ling Shao