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Federated learning (FL) is a distributed learning paradigm that allows multiple decentralized clients to collaboratively learn a common model without sharing local data. Although local data is not exposed directly, privacy concerns…

Machine Learning · Computer Science 2024-10-02 Tongxin Yin , Xuwei Tan , Xueru Zhang , Mohammad Mahdi Khalili , Mingyan Liu

Collaborative clinical decision support is often constrained by governance and privacy rules that prevent pooling patient-level records across institutions. We present a hybrid privacy-preserving framework that combines Federated Learning…

Machine Learning · Computer Science 2026-02-18 Farzana Akter , Rakib Hossain , Deb Kanna Roy Toushi , Mahmood Menon Khan , Sultana Amin , Lisan Al Amin

Federated learning (FL) is a distributed machine learning technique designed to preserve data privacy and security, and it has gained significant importance due to its broad range of applications. This paper addresses the problem of optimal…

Statistics Theory · Mathematics 2025-01-16 Tony Cai , Abhinav Chakraborty , Lasse Vuursteen

Federated learning (FL) is a decentralized method enabling hospitals to collaboratively learn a model without sharing private patient data for training. In FL, participant hospitals periodically exchange training results rather than…

Cryptography and Security · Computer Science 2022-08-24 S. Maryam Hosseini , Milad Sikaroudi , Morteza Babaei , H. R. Tizhoosh

AI methods are increasingly shaping pharmaceutical drug discovery. However, their translation to industrial applications remains limited due to their reliance on public datasets, lacking scale and diversity of proprietary pharmaceutical…

Machine Learning · Computer Science 2026-05-07 Markus Bujotzek , Evelyn Trautmann , Calum Hand , Ian Hales

We present the Differentially Private Blockchain-Based Vertical Federal Learning (DP-BBVFL) algorithm that provides verifiability and privacy guarantees for decentralized applications. DP-BBVFL uses a smart contract to aggregate the feature…

Cryptography and Security · Computer Science 2024-07-10 Linh Tran , Sanjay Chari , Md. Saikat Islam Khan , Aaron Zachariah , Stacy Patterson , Oshani Seneviratne

The use of collaborative and decentralized machine learning techniques such as federated learning have the potential to enable the development and deployment of clinical risk predictions models in low-resource settings without requiring…

Machine Learning · Computer Science 2019-11-15 Stephen R. Pfohl , Andrew M. Dai , Katherine Heller

Federated learning (FL), as a type of distributed machine learning, is capable of significantly preserving client's private data from being shared among different parties. Nevertheless, private information can still be divulged by analyzing…

Machine Learning · Computer Science 2024-02-06 Adrien Banse , Jan Kreischer , Xavier Oliva i Jürgens

Along with the blooming of AI and Machine Learning-based applications and services, data privacy and security have become a critical challenge. Conventionally, data is collected and aggregated in a data centre on which machine learning…

Cryptography and Security · Computer Science 2021-03-19 Nguyen Truong , Kai Sun , Siyao Wang , Florian Guitton , Yike Guo

Large volumes of medical data remain underutilized because centralizing distributed data is often infeasible due to strict privacy regulations and institutional constraints. In addition, models trained in centralized settings frequently…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Puja Saha , Eranga Ukwatta

The digitization of healthcare has generated massive volumes of Electronic Health Records (EHRs), offering unprecedented opportunities for training Artificial Intelligence (AI) models. However, stringent privacy regulations such as GDPR and…

Cryptography and Security · Computer Science 2026-02-04 Rodrigo Tertulino , Ricardo Almeida , Laercio Alencar

Trustworthy artificial intelligence (AI) technology has revolutionized daily life and greatly benefited human society. Among various AI technologies, Federated Learning (FL) stands out as a promising solution for diverse real-world…

Machine Learning · Computer Science 2023-02-22 Yifei Zhang , Dun Zeng , Jinglong Luo , Zenglin Xu , Irwin King

Federated Learning (FL) aims to protect data privacy by enabling clients to collectively train machine learning models without sharing their raw data. However, recent studies demonstrate that information exchanged during FL is subject to…

Machine Learning · Computer Science 2024-12-11 Pengxin Guo , Shuang Zeng , Wenhao Chen , Xiaodan Zhang , Weihong Ren , Yuyin Zhou , Liangqiong Qu

Federated learning (FL) is a collaborative machine learning paradigm which ensures data privacy by training models across distributed datasets without centralizing sensitive information. Vertical Federated Learning (VFL), a kind of FL…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-13 Nikita Shrivastava , Drishya Uniyal , Bapi Chatterjee

Federated Learning (FL) is a paradigm for large-scale distributed learning which faces two key challenges: (i) efficient training from highly heterogeneous user data, and (ii) protecting the privacy of participating users. In this work, we…

Machine Learning · Computer Science 2023-01-06 Maxence Noble , Aurélien Bellet , Aymeric Dieuleveut

Machine learning (ML) methods have been widely used in genomic studies. However, genomic data are often held by different stakeholders (e.g. hospitals, universities, and healthcare companies) who consider the data as sensitive information,…

Cryptography and Security · Computer Science 2020-03-03 Cheng Hong , Zhicong Huang , Wen-jie Lu , Hunter Qu , Li Ma , Morten Dahl , Jason Mancuso

Diffusion models have shown great potential for vision-related tasks, particularly for image generation. However, their training is typically conducted in a centralized manner, relying on data collected from publicly available sources. This…

Machine Learning · Computer Science 2023-11-29 Ye Lin Tun , Chu Myaet Thwal , Ji Su Yoon , Sun Moo Kang , Chaoning Zhang , Choong Seon Hong

Federated Learning (FL) is an interesting strategy that enables the collaborative training of an AI model among different data owners without revealing their private datasets. Even so, FL has some privacy vulnerabilities that have been…

Machine Learning · Computer Science 2025-06-13 Xavier Martínez Luaña , Rebeca P. Díaz Redondo , Manuel Fernández Veiga

Federated learning with differential privacy, or private federated learning, provides a strategy to train machine learning models while respecting users' privacy. However, differential privacy can disproportionately degrade the performance…

Machine Learning · Computer Science 2022-04-18 Borja Rodríguez-Gálvez , Filip Granqvist , Rogier van Dalen , Matt Seigel

The fusion of complementary multimodal information is crucial in computational pathology for accurate diagnostics. However, existing multimodal learning approaches necessitate access to users' raw data, posing substantial privacy risks.…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Yuanzhe Peng , Jieming Bian , Jie Xu